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Coherent X-ray imaging techniques, such as in-line holography, exploit the high brilliance provided by diffraction-limited storage rings to perform imaging sensitive to the electron density through contrast due to the phase shift, rather than conventional attenuation contrast. Thus, coherent X-ray imaging techniques enable high-sensitivity and low-dose imaging, especially for low-atomic-number (Z)
Purpose: To investigate long-term trends and changes in the pattern of use of lamotrigine (LTG). Methods: Retrospective survey of a large, routine therapeutic drug monitoring database. Results: Twelve thousand one hundred and seven samples from 4123 subjects were analysed from October 1999 to May 2007. Within this period, the mean daily dose rose from 183 to 253 mg, whereas the median dose remaine
Being deeply embedded in the mythological framework of old-school Christian angelology, the theodicy presented in this article outlines a thoroughgoing and unexpectedly simple solution to the problem of evil. Unlike other Satan-oriented theodicies, whose central idea is that natural evil is reducible to moral evil by taking the malevolent actions of demons into consideration, it accounts for both
The interface of the oceans and aqueous aerosols with air drives many important physical and chemical processes in the environment, including the uptake of CO2 by the oceans. Transport across and reactions at the ocean-air boundary are in large part determined by the chemical composition of the interface, i.e., the first few nanometers into the ocean. The main constituents of the interface, beside
This study examines how public transport passengers experience and use travel time and under what conditions they are particularly concerned about shorter travel time. Using a survey of Swedish public transport users and a follow-up focus group, we compare current patterns with a similar 2009 study. Findings indicate a slight decline in perceived value of travel time, coinciding with a marked redu
This paper examines the distributive effects of personal income taxation in Sweden, the United Kingdom, and the United States during the first half of the twentieth century. We estimate the evolution of marginal and average effective tax rates across the income distribution and calculate the corresponding indices of progressivity and redistribution. Our results show that redistribution through inc
Infections are a common reason for hospitalization, and when an infection is accompanied by organ failure, the patient is considered to have sepsis. The most severely ill sepsis patients are treated in the Intensive Care Unit (ICU). Identifying sepsis at ICU admission is, however, challenging, since most ICU patients present with organ failure and there is no gold standard for infection diagnosis.
Intracellular deposits of neurofibrillary tau tangles and extracellular Aβ plaques are closely associated with Alzheimer’s disease. The mapping of thermodynamic parameters, including solubility limits, indicates when a protein forms amyloid fibrils or remains in solution. This reveals the direction of change of the system and may help in understanding drift and steady states in living systems. Her
The clustering of certain proteins into oligomers and fibrils, known as amyloids, underlies the pathology of diseases such as Alzheimer’s disease, Parkinson’s disease, and type 2 diabetes. These processes are counteracted by the cellular protein quality control system, which includes molecular chaperones that interact with disease-associated proteins. One such chaperone is DNAJB6b, which has gaine
This paper studies the sources of the Russia–Ukraine conflict. The prerequisites for this conflict began when, in Ukraine and Russia, the liberal tendencies that emerged after the collapse of the USSR gave way to conservatism. The differences between the current state ideologies of the two countries are demonstrated through a comparative analysis of 16 Russian and Ukrainian school history and lite
The tenth-century Byzantine hagiographical Life of Theoktiste, written by Niketas Magistros, has been read in various ways, not in the least intertextually and as the life of a non-existing saint. The present article further investigates the motives of the author, the social and cultural vision, as well as generic notions, embedded in the text, and offers a new date of composition for the Life, vi
This study is a literature review of three market-based instruments used for land management; environmental offsets, payments for ecosystem services (PES) and certification, and how they could be used to mitigate environmental impacts from sugarcane cultivation in Brazil when purchasing biopolymers. The study showed that certification is the most common market-based instrument in Brazil. Offset an
Quantum effects at the nanoscale offer significant potential for future device technologies. A quantum dot heat engine, for instance, is able to convert heat into electrical current. This thesis investigates the transport properties and current fluctuations in a single-level quantum dot heat engine operating in the sequential tunneling regime. Based on the existing experimental data, both the curr
Tourism is often being viewed as one of the worlds largest sectors and a great contribution to growth and development. There is a large motivation amongst developing countries to promote themselves as a tourist destination, since they expect the tourism to generate economic growth. The government of Thailand has been promoting tourism since 1960, and the number of foreign visitors has increased fr
The CARIFORUM and the EU agreed in December 2007 on an EPA which replaced the preferential trade treatment granted by the EU under the Lomé convention and Cotonou agreement. In the EPA the EU agreed to open up their markets to 100% for goods coming from the CARIFORUM (rice and sugar have shorter transition periods) and the CARIFORUM has 25 years to liberalize 86,9% of imports coming from the EU. T
Technological development, in particular the development of information and communicatiion technologies (ICT), is often presented as the answer to many social problems. Proponents of the Information Society suggest that poverty, failing integration, unemployment, and llack of democracy can be addressed with the appropriate technological means. Inequality iis often framed in terms of a digital divi
