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Projections estimate that by 2050 hundreds of millions to a billion people will migrate elsewhere due to environmental reasons. The increasing frequency and intensity of natural hazards posed by climate change, as well as the slow-onset degradation of habitats all over the planet, will drive more and more species to migrate towards more habitable and safe environments. While much of the literature
Objective: Oxidation of LDL plays a key role in the development of atherosclerosis. HDL may, in part, protect against atherosclerosis by inhibiting LDL oxidation. Overexpression of HDL-associated apolipoprotein M (apoM) protects mice against atherosclerosis through a not yet clarified mechanism. Being a lipocalin, apoM contains a binding pocket for small lipophilic molecules. Here, we report that
Background. Oestrogen receptor (ER) status is important for the choice of systemic treatment of breast cancer patients. However, most data from randomised trials on the effect of adjuvant endocrine therapy according to ER status are based on the cytosol methods. Comparisons with immunohistochemical methods have given similar results. The aim of the present study was to examine whether different ER
As the population is growing and planetary boundaries are being strained, the agro-food industry is facing major challenges. Previous research has proposed the innovation of vertical farming (VF) as a potential solution. This study contributes to the existing VF literature with an examination of the opportunities and obstacles for the implementation and upscaling of VF in Sweden. The VF industry i
The present study aimed to investigate if celebrity (knowledge/semantic memory) can have protective functions against memory errors. We examined if famous faces, based on an interaction of semantic and episodic memory can lead to a deeper encoding, and if attractive faces, based on familiarity can lead to more confusion. Participants' ability to distinguish between studied and nonstudied faces
The present study investigated whether emotions influence participants' memory judgements. A special attention was paid to episodic memory. The experiment investigated participants' memory for faces and its main goal was to study whether facilitated episodic memory could lead to a lowered susceptibility to memory errors especially in regard to negative faces. The experiment consisted of tw
Conflicts of interests between males and females over reproduction is a universal feature of sexually reproducing organisms and has driven the evolution of intersexual mimicry, mating behaviours and reproductive polymorphisms. Here, we show how temperature drives pre-reproductive selection in a female colour polymorphic insect that is subject to strong sexual conflict. These species have three fem
Lung cancer and chronic lung diseases impose major disease burdens worldwide and are caused by inhaled noxious agents including tobacco smoke. The cellular origins of environmental-induced lung tumors and of the dysfunctional airway and alveolar epithelial turnover observed with chronic lung diseases are unknown. To address this, we combined mouse models of genetic labeling and ablation of airway
The number of medically fragile children cared for at home is increasing; however, there are few studies about the professional support these families receive in their homes. The aim of the study was to understand the meanings that parents had about the support they received from health care professionals who offered care for their ventilator-assisted child in the family home. A phenomenological-h
We all want to develop impactful and valuable theories, but what do we mean by ‘theory’? In this piece, we reply to the four readers’ comments on a recent paper in which we propose a theory typology that, in comparison to existing literature, offers a considerably broader, more pluralistic and, at the same time, more precise definition of the meaning(s) of ‘theory’ within academia. In their commen
Purpose: In the last decade, the research community has focused on defining reliable biomarkers for the early detection of Alzheimer’s disease (AD) pathology. In 2017, the Geneva AD Biomarker Roadmap Initiative adapted a framework for the systematic validation of oncological biomarkers to cerebrospinal fluid (CSF) AD biomarkers—encompassing the 42 amino-acid isoform of amyloid-β (Aβ42), phosphoryl
This article builds on recent works on witnessing, socially engaged documentary filmmaking and studies on the role of new digital technologies for witnessing trauma, recording memories and enabling activism. In a devastating earthquake in Sichuan province on 12 May 2008, almost 90,000 people, at least 5000 of them being children, died. Parents and bystanders provided the first footage of the earth
The last Catholic archbishop of Sweden to hold residence in his see at Uppsala, Johannes Magnus (1488-1544), was the author of a major work about Swedish history: the Historia de omnibus Gothorum Sueonumque regibus. Johannes Magnus left Sweden in 1526, spent the rest of his life away from his home country and eventually died in Rome, where his work was published posthumously in 1554. One reason fo
Objectives. The arachidonate 5-lipoxygenase activating protein (ALOX5AP) regulates synthesis of leukotrienes (LTs), which are important mediators of inflammation and connective tissue remodelling. The aim of this study was to evaluate if single nucleotide polymorphisms (SNPs) of ALOX5AP confer risk of SSc and/ or SSc-related organ involvement. Methods. Seven SNPs of ALOX5AP (rs17222814, rs17216473
Living labs as a research approach have been said to hold many promises regarding the evaluation of state-of-the art technologies in real-world contexts, for instance by allowing close cooperation with various stakeholders. At the same time, a living lab approach is connected with substantial complexity and increased risk. This paper elaborates on a conducted living lab with the objective to explo
