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The spontaneous open-field behavioural effects of 10 days of chronic treatment with two clinical doses (10 and 20 mg/kg daily) and one high/toxic dose (100 mg/kg daily) of the selective serotonin reuptake inhibitor citalopram (delivered subcutaneously by implanted osmotic pumps) were examined in rats. Central and peripheral arena locomotor and rearing activities were recorded simultaneously, and t

To examine whether lower insulin sensitivity as determined by homeostatic model assessment (HOMA-%S) was associated with increased left ventricular mass (LVM) and presence of LV diastolic dysfunction at long-term follow-up, independently of body mass index (BMI), in middle-aged, otherwise healthy males.

Extracellular signal-regulated kinase (ERK) 1/2 signalling mediates communication between growth factor receptors and the cell nucleus and has been linked to several key events in the transformation process such as proliferation and invasion. We therefore sought to delineate the degree of phosphorylated ERK1/2 in breast cancer and potential links to upstream receptors such as VEGFR2, ErbB2, downst

Streptococcus equi subsp. zooepidemicus is an important pathogen in horses that causes severe diseases such as pneumonia and abortion. Furthermore, it is a zoonotic agent, and contact with horses is a known risk factor. In this study, we investigated the working hypothesis that the zoonotic potential varies among S. equi subsp. zooepidemicus strains in association with differences in M-like protei

The importance of nucleic acids in pure form for preparative and analytical perspectives, have increased constantly, demanding the development of new and more efficient methods for their recovery and isolation. This thesis describes a series of different innovative methods for recovery and purification of these biomolecules. In a general overview of a downstream processing, there are several criti

This study was designed to test the hypothesis that administration of granulocyte colony-stimulating factor (G-CSF; filgrastim) during induction chemotherapy with CHOP (cyclophosphamide, vincristine, doxorubicin, prednisone) or CNOP (doxorubicin replaced with mitoxantrone) in elderly patients with aggressive non-Hodgkin lymphoma (NHL) improves time to treatment failure (TTF), complete remission (C

NOVEMER NO.3 MÅNADSBREV FRÅN DET MODEVETENSKAPLIGA STUDIERÅDET ORD FRÅN ORDFÖRANDE Förändringarnas vindar blåser. Vogue Paris har blivit Vogue France, eftersom “identitet inte definieras utifrån ett stäl- le”. Vogue France ska alltså (till skill- nad från Vogue Paris?) upphöja indi- vidualism och fira friheten att vara den man är oavsett var man kommer ifrån, enligt den nya chefredaktören Eugénie

https://www.kultur.lu.se/fileadmin/user_upload/kultur/Utbildning/Mode_maanadsbrev/Ma__nadsbrev_NOVEMBER_-_MVS.pdf - 2026-07-04

In this study we describe the morphological and genetic analysis of the Drosophila mutant gurtelchen (gurt). gurt was identified by screening an EMS collection for novel mutations affecting visceral mesoderm development and was named after the distinct belt shaped visceral phenotype. Interestingly, determination of visceral cell identities and subsequent visceral myoblast fusion is not affected in

Background: The contribution of smoking to rheumatoid arthritis (RA) is hypothesized to be mediated through formation of anti-citrullinated protein antibodies (ACPA). In RA, however, autoantibodies such as ACPA, rheumatoid factor (RF), and anti-carbamylated protein antibodies (anti-CarP) often occur together, and it is thus unclear whether smoking is specifically associated with some autoantibodie

Verksamhetsplan 2018 för EBSCO Systems Nordic User Group Antagen av styrelsen: 2018-05-09 Styrelsen ska under verksamhetsåret fortsätta arbetet med att komma med förslag på förbättringar i de EBSCO system som gruppens medlemmar använder och att utveckla kontakten och samarbetet mellan bibliotek och organisationer kring desamma. För att vara en relevant användargrupp är styrelsen beroende av att me

https://www.ub.lu.se/sites/ub.lu.se/files/verksamhetsplan_2018_for_eds_nordic_user_group.pdf - 2026-07-05