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Objective: Progressive multiple sclerosis is characterized by chronic inflammation with microglial activation, oxidative stress, accumulation of iron and continuous neurodegeneration with inadequate effectiveness of medications used so far. We now investigated effects of iron on microglia and used the previously identified neuroprotective antipsychotic clozapine in vitro and in chronic experimenta
There is a major contradiction between the current model of international elite sport and efforts to mitigate climate change. This study investigates climate action delay discourses within the sports sector by analyzing 28 semi-structured interviews with athletes and sports federation employees. Based on the two climate delay discourse typologies of Lamb et al. (2020, Global Sustainability, 3: e17
Bladder cancer is a fast-moving and recurrent malignancy where survival hinges on early detection and precise risk stratification. The search for robust biomarkers is urgent, and CD44v6 has emerged as a compelling candidate. In this study, we explored the clinical and functional associations of CD44v6 expression in bladder cancer. Integrated analyses of patient samples and cell lines showed that h
This study is an effort to find a connection between the high number of people on sick leave, the occupational health situation at the workplace, and stronger market competition and globalisation forces. The basis for the study is statistics, mainly on injuries and diseases, interviews with people in different positions with either long experience within the safety and health situation or otherwi
Patients with pancreatic ductal adenocarcinoma (PDAC) commonly develop symptoms and signs in the 1-2 years before diagnosis that can result in changes to medications. We investigate recent medication changes and PDAC diagnosis in Nurses' Health Study (NHS; females) and Health Professionals Follow-up Study (HPFS; males), including up to 148,973 U.S. participants followed for 2,994,057 person-years
We have studied excitation energy transfer in the photosynthetic antenna systems LH1 and LH2 of purple bacteria. Femtosecond pump-probe experiments were combined with computer simulations using the recently established structure of these systems to assess the nature of electronic excitation. We have measured the transient absorption kinetics and spectra of the LH1 and LH2 complexes in the tem
Liver-generated plasma apolipoprotein E (apoE) does not enter the brain but nonetheless correlates with Alzheimer's disease (AD) risk and AD biomarker levels. Carriers of APOEε4, the strongest genetic AD risk factor, exhibit lower plasma apoE and altered brain integrity already at mid-life versus non-APOEε4 carriers. Whether altered plasma liver-derived apoE or specifically an APOEε4 liver phenoty
Neuroblastoma is a childhood developmental cancer; however, its embryonic origins remain poorly understood. Moreover, in-depth studies of early tumor-driving events are limited because of the lack of appropriate models. Herein, we analyzed RNA sequencing data obtained from human neuroblastoma samples and found that loss of expression of trunk neural crest–enriched gene MOXD1 associates with advanc
High interstitial fluid pressure (IFP) in colorectal cancer metastases may decrease the uptake and, thus, the effects of anti-tumor drugs. Imatinib, a selective inhibitor of PDGF receptors, and anakinra, an interleukin-1 receptor antagonist, respectively, increase drug uptake and/or decrease IFP in preclinical models of carcinoma. Drug-induced decrease in IFP in human metastases has not been objec
There is a vivid interest in so-called epimilitary narratives of war that depart from heroic themes and zoom out from the armed forces. This article joins this direction by analyzing two variants of cultural narratives of the war in Bosnia-Hercegovina during the 1990s and the siege of Sarajevo: the videogame This War of Mine and Bosnian citizens’ personal stories told in qualitative interviews. Bo
Greetings from Sune Sunesson, Director It has been a busy couple of months for the Pufendorf IAS (Pufendorfinstitutet). Now it is almost summer and we would like to take the opportunity to wish all of you a very enjoyable break. It is our ambition that the newsletter will become an arena for sharing news and information about current or completed transdisciplinary work - so please email us if you
Bilaga 1 Verksamhetsberättelse 2017 för EDS Nordic User Group Vid EDS Nordic User Groups årsmöte 2017-03-22 i Luleå valdes följande styrelsemedlemmar: ordförande Cilla Öhnfeldt, Stockholms universitet (omval), Per Falk, Högskolan i Gävle (nyval), Ann- Christin Persson, Lunds universitet (nyval), Tove Andersson, Region Skåne (nyval), Mikael Arvidsson, Karlstads universitet (omval) och Eva Sejmyr, L
https://www.ub.lu.se/sites/ub.lu.se/files/verksamhetsberattelse_2017_for_eds_nordic_user_group.pdf - 2026-07-05
LL_KSMB25_rev190130 Litteraturlista för Konsumtion, identitet och kommunikation, 15 hp (KSMB25) Litteraturlistan är fastställd av styrelsen för institutionen för service management och tjänstevetenskap 2017-01-25, senast reviderad 2019-01-30. Litteraturlistan börjar gälla 2019-02-01. Aldridge, Alan. (2003). Consumption. Cambridge, UK: Polity. [s. 15-22, ISBN 0-7456-2529-0] Bengtsson, Anders & Östb
https://www.ses.lu.se/sites/ses.lu.se/files/ll_ksmb25_rev190130.pdf - 2026-07-05
