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Intracellular membrane fusion is coordinated by membrane-anchored fusion proteins. The cytosolic domains of these proteins form a specific complex that pulls the membranes into close proximity. Although some results indicate that membrane merger can be accomplished solely on the basis of proximity, others emphasize the importance of bilayer stress exerted by transmembrane peptides. In a reductioni
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Den europeiska varumärkesrätten är under förändring och nyligen antog Europaparlamentet ett nytt varumärkesdirektiv och en ny varumärkesförordning. En av de frågor som har varit mest omdiskuterad inför förändringarna är huruvida det räcker med användning av ett varumärke i en medlemsstat för att det territoriella kriteriet som är kopplat till bedömningen av verkligt bruk ska anses uppfyllt i artikThe European trademark law is under revision and recently the European Parliament adopted a new Community Trademark Regulation and a new Trademark Directive. One of the most discussed issues concerning the new legislation is weather it is sufficient to use a trademark in one member state to fulfill the requirement of genuine use in Article 15.1 in the Community Trademark Regulation. Previously the
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This paper reviews evidence from human physiology as to which foods may have been typically consumed by the hominin ancestral lineage up to the advent of anatomically modern humans. Considerable evidence suggests that many common diseases can be prevented by hunter-gatherer diets. Apparently, human nutritional metabolism is not perfectly fine-tuned for recently introduced staple foods, such as cer
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Emotion regulation has been specifically linked to both non-suicidal self-injury (NSSI) and attempted suicide. It is also known that self-harm is disproportionally higher (30–68.4%) in forensic samples than in the general population, yet knowledge about the association between emotion regulation and self-harm in forensic settings is scarce. The purpose of this study was to describe emotion regulat
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Species’ range shifts and local extinctions caused by climate change lead to community composition changes. At large spatial scales, ecological barriers, such as biome boundaries, coastlines, and elevation, can influence a community's ability to shift in response to climate change. Yet, ecological barriers are rarely considered in climate change studies, potentially hindering predictions of biodiv
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In this paper, the impact of laminated steel ring cores’ geometric properties on core losses is investigated by means of inferential statistics. In particular, iron loss standardized measurements taken upon ring core specimens that underwent identical manufacturing processes, are compared via two-sample t-tests to establish the existence of statistically significant differences between the samples
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När jag hade flöjtlektioner på kulturskola värderades inte musiken efter genrer. Min upplevelse var att flera olika genrer förekom lika ofta på lektionerna. När jag senare sökte in till musikhögskolan och var tvungen att välja genre rubbades denna bild och jag frågade mig vad min roll som flöjtpedagog kommer vara. Ska jag nischa mig inom en genre, eller ska jag kunna lära ut lite av varje? SyftetWhen I had flute lessons at the community school of music and art, music was not valued according to genres. My experience was that several different genres were equally common in the lessons. When I later applied to Malmö Academy of Music, and had to choose a genre, this idea was disrupted and I asked myself what my role as a flute teacher would be. Should I specialize myself within a genre, or s
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Changes to the Education Act in 2025 will mean that school libraries will have a specific objective of promoting students' reading and media and information literacy. Meanwhile, school library spaces can vary greatly in terms of accessibility and size. The aim of this thesis is therefore to provide knowledge about how the work of school librarians is affected by the possibilities and limitatio
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Antibody evolution in vivo proceeds mainly by stepwise improvements, accomplished by single base pair substitutions. Lately, receptor revision, i.e. exchange of large parts of the V gene for another sequence, has been suggested to provide a complementary route for affinity maturation. By employing a receptor revision like evolution process in vitro using combinatorial libraries and phage display s
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Background: Neuroimaging with magnetic resonance imaging (MRI) may assist clinicians in evaluating brain injury and optimising care in comatose adults resuscitated after out-of-hospital cardiac arrest (OHCA). However, contemporary international data on its use are lacking. Aim: The primary aim was to compare the patient characteristics, early postresuscitation care, and neurological outcomes of pa
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The eighteenth century marks a watershed in European intellectual history. It witnessed the development of many civil rights ideas that were prerequisites for the emergence of modern political systems. One principle that appears to be supported by numerous empirical examples is that evolving political pluralism fostered the right to express one’s views with a certain degree of freedom. This articl
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Publication in human gene therapy
Regulated Delivery of Glial Cell Line-Derived Neurotrophic Factor into Rat Striatum, Using a Tetracycline-Dependent Lentiviral Vector HUMAN GENE THERAPY 15:934–944 (October 2004) © Mary Ann Liebert, Inc. Regulated Delivery of Glial Cell Line-Derived Neurotrophic Factor into Rat Striatum, Using a Tetracycline-Dependent Lentiviral Vector BILJANA GEORGIEVSKA,* JOHAN JAKOBSSON,* ELISABETH PERSSON, CEC
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This thesis explores the legal position of permanent residents as compared to that of citizens in the case study of Georgia. With this aim, the thesis first examines the general legal system of the case study and delves into its sphere-specific regulations, which restrict access to different areas of life to permanent residents. The thesis then applies the standards extrapolated from the internati
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Den 8 juli 2019 meddelade ICC en fällande dom mot kongolesiske befälhavaren Bosco Ntaganda som var åtalad för bland annat våldtäkt som brott mot mänskligheten. I mars 2021 fastställdes den överklagade domen av ICC:s appellationskammare och blev således den första i historien att döma en enskild individ till personligt ansvar för bland annat våldtäkt som brott mot mänskligheten. Sexuellt våld i vOn 8 July 2019, ICC Trial Chamber VI found Congolese commander Bosco Ntaganda guilty for rape as a crime against humanity. In March 2021, the appealed verdict was upheld by the Appeals Chamber of the ICC, making it the first conviction in history to sentence someone as individually criminally responsible for rape as a crime against humanity. Sexual violence in armed conflicts has been a highly to
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Institutet strafföreläggande införs i svensk rätt år 1948. Syftet med systemet är att effektivt kunna lagföra lindriga och enkla brott, till exempel ringa stöld och olovlig körning. Brottmålsförfarandet tillåter den misstänkte att godkänna ett av åklagaren utfärdat strafföreläggande som avser en påföljd för ett begånget brott. Om den anklagade accepterar strafföreläggandet avstår han eller hon fråThe summary imposition of a fine is introduced into Swedish law in 1948. The purpose of the system is to take legal proceedings more efficiently against minor and simple criminal cases, such as petty theft and unlawful driving. The criminal procedure allows the suspect to approve an injunction filed by the prosecutor regarding a punishment for a committed crime. If the accused accepts the injuncti
