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Chronic pulmonary disease is a recognized risk factor for invasive pneumococcal disease (IPD). However, previous studies have often not been large enough to allow detailed analyses of less prevalent pulmonary diseases, and findings regarding case fatality have been inconsistent. We examined the associations between an underlying pulmonary disease and IPD, and the impact of these diseases on the ca
The atrial activity of the human heart is normally visible in the ECG as a P-wave. In patients with intermittent atrial fibrilation, a different P-wave morphology can sometimes be seen, indicating atrial conduction defects. The purpose of this study was to develop a method to discriminate between such P-waves and normal ones. 20 recordings of each type were used in a classification which, based on
Popular Abstract in Swedish Människans immunförsvar har utvecklats under miljontals år för att i bästa möjliga mån skydda oss från infektioner och det sköter i de allra flesta fall det jobbet utmärkt. Ibland händer det dock att någonting går fel och konsekvensen kan bli väldigt obehaglig eller till och med förödande för den drabbade. Allergiska reaktioner är ett utmärkt exempel på en sådan situatiAntibodies of the IgE isotype play a key role as the allergen recognizer in allergic disease, which today affects as much as a third of the population in the industrialized parts of the world. Despite this crucial role of IgE, our knowledge of IgE repertoires and how we can utilize the information hidden in monoclonal IgE to improve the quality of life of allergic patients, is limited. This thesis
The article examines the reception of Old Testament motifs in the so called "Hymn of the Pearl" (preserved in Syriac and Greek as part of the apocryphal Acts of Thomas). Ideas taken up for study include the use of "Egypt" as a symbol of spiritual bondage, the legacy of the West Semitic Chaoskampf motif, the link to Ezekiel 32:2, etc. The main thrust of the article is the transformation of ancient
Purpose: The purpose of this paper is to investigate how co-branding can be utilized by heritage brands to rejuvenate. The aim is to develop the current understanding of how heritage brands engage in co-branding and the motives for rejuvenating the brand. Design/Methodology/Approach: This conceptual paper adopts a theory about the five elements to identify heritage brands as first introduced by Ur
Abstract Purpose: The purpose of this paper is to conceptualize and investigate those relationships that occur when customers feel embarrassed of their buying behaviour. Methodology: A qualitative research method has been chosen to conduct this research. Primary data has been collected through two focus groups and three interviews. Secondary data, in the form of literature review and examples of
Context: Dopamine agonists are the treatment of choice for prolactinomas and symptomatic idiopathic hyperprolactinemia. However, the optimal treatment strategy and treatment duration is not clear in all details. Objective: The aim of the study was to assess the effect of dopamine agonist withdrawal in patients with idiopathic hyperprolactinemia and prolactinomas. Data Sources: PubMed, the Cochrane
Autologous dermal fibroblasts may be useful in the treatment of diabetic skin wounds. We hypothesized that cultured fibroblasts or cultured keratinocytes would not only survive in a hyperglycemic wound environment but also enhance the rate of re-epithelialization. We previously developed a new porcine model of delayed cutaneous wound healing in the diabetic pig. Full thickness wounds were created
To find a controller that provides the maximal stability margin to an LTI system under rank-one perturbations is a quasiconvex problem. In the paper, the dual quasiconvex problem is obtained, using the convex duality arguments in the Hardy space H∞. It is shown that the dual problem can be viewed as minimization of a "length" of uncertainties that destabilize the system. Several examples establish
Antibody-based microarrays are among the new, rapidly emerging technologies within the field of proteomics that has the potential to evolve into a key proteomic research tool, providing novel means to perform early diagnostics, identify biomarkers and gain insights into disease biology. The aim of this thesis, based on five original papers, was to develop antibody microarrays based on human recom
