Filtyp
Long life requires individuals to defend themselves against pathogens over prolonged periods of time whilst minimising damage to themselves. In vertebrates, pathogen defence is provided by two integrated systems, innate and adaptive immunity. Innate immunity is relatively nonspecific, resulting in collateral damage to hosts, and does not involve canonical immunological memory. In contrast, adaptiv
In 1798 the Royal Academy of Science instituted a classification of its members, designating the last class to be filled by those engaged with world of learning and beautiful arts. This study maps the population of this “erudite class” and analyzes the negotiation of epistemic virtues and merits linked to the nebulous field from which the class drew its members. The article argues that a previous
Poland and polish courts have been the subject of much attention during recent years, because of alleged problems in relation to the organisation of justice in Poland. It has been claimed that new suggested legislation in Poland, and changes in the system for appointing judges, prevents courts in Poland from adjudicating justice in a fair and independent manner in accordance with the Rule of Law.
This chapter outlines how the history of health care in Syria has shaped the way in which wartime health care has been delivered and controlled. The chapter analyzes the claim by humanitarian organizations to a form of neutrality in the Syrian war, which was ultimately incompatible with the way the Syrian state and the opposition saw aid delivery as part of the battle for statehood. It also mentio
Background: There has been a global increase in the number of people who are dying of old age. This development implies a need for good palliative care among older persons at the end of life. Here nursing homes have an important role to play. However, the principles of palliative care have not been sufficiently applied in nursing homes, and there is a need to increase the implementation of palliat
The aim of this report is to survey the risks connected with home for old people to be able to enhance security and decrease the inherent risks. The goal is to create a tool that will facilitate working with risk management at home for old people, and thus be able to increase security in daily life for the people who live there as well as for personnel and visitors. The starting point of this repo
Att arbetsmarknaden är i ständig förändring råder det ingen tvekan om. Produktionen av både tjänster och varor efterfrågar nya former för förvärvande av arbetsprestationer. Mer eller mindre nya grepp inom företagsvärlden som till exempel utkontraktering och projektanställningar vittnar om detta. Förändringarna gör att gränsdragningen mellan att vara arbetstagare och uppdragstagare inte kan förväntThe labour market is constantly changing. The production of both services and goods are now acquiring labour in new forms. More or less new tendencies in business management such as outsourcing and project assignments are realities today. These changes add complexity to the process of defining whether a person, the work performing part, is to be considered as employed by the principal or as an ent
We investigate how the anchoring effect—a well-established cognitive bias—influences the full distribution of subjective beliefs. While prior research extensively examines the impact of anchoring and other biases on point estimates, their effect on higher moments of the distribution remains unexplored. Through a pre-registered online experiment (N=732), we find that anchoring impacts the mean, var
Ligand selectivity among the highly conserved galectins has been an ever-challenging objective. For galectin-8, a protein prevalent in both pathology and tissue distribution, we report phthalazinone-galactals that show excellent selectivity for the galectin-8N-terminal domain. A dissection of structure–activity relationships of the phthalazinone and an extensive molecular dynamics meta-analysis ac
Despite decades of research on the pathophysiology of depression, the development of new therapeutic interventions has been slow, and no biomarkers of treatment response have been clinically implemented. Several lines of evidence suggest that the clinical and biological heterogeneity among patients with major depressive disorder (MDD) has hampered progress in this field. MDD with low-grade inflamm
Tomography technology is not usual when investigating drilled asphalt cores properties. Currently, there is no internationally recognised standard tomography method for asphalt pavements. Tomography provides, however, a non-destructive alternative to traditional, usually destructive, testing of drilled cores. Furthermore, tomography offers possibilities, which traditional laboratory analyses do no
The North-Western Sahara Aquifer System (NWSAS) shared by Libya, Tunisia, and Algeria is one of North Africa’s biggest nonrenewable groundwater storage systems. The management of its resources in a sustainable way will be central to regional stability, food security, and climate resilience. This book chapter discusses how transboundary cooperation along the NWSAS has evolved through facilitation b
