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Ensuring functional safety is a critical challenge for autonomous robots, as they must operate reliably and predictably despite uncertainty. However, existing safety measures can over-constrain the system, limiting the robot’s availability to perform its assigned task. To address this problem, we propose a more flexible strategy that equips robots with theability to adapt to system failures and re

Context: DevOps has recently become a mainstream solution for bridging the gaps between development (Dev) and operations (Ops) enabling cross-functional collaboration. The DevOps concept of continuous monitoring may bring a lot of benefits to development teams such as early detection of run-time errors and various performance anomalies. Objective: We aim to explore deep learning (DL) solutions for

The efficiency with which flying animals convert metabolic power to mechanical power dictates an individual's flight behaviour and energy requirements. Despite the significance of this parameter, we lack empirical data on conversion efficiency for most species as in vivo measurements are notoriously difficult to obtain. Furthermore, conversion efficiency is often assumed to be constant across flig

Assertions are one of the most useful automated techniques for checking program’s behaviour and hence have been used for different verification and validation tasks. We provide an overview of the last two decades of research involving ‘assertions’ in software testing. Based on a term–based search, we filtered the inclusion of relevant papers and synthesised them w.r.t. the problem addressed, the s

Study Design Controlled laboratory study; cross-sectional. Background Postural control following anterior cruciate ligament reconstruction (ACLR) primarily has been investigated during static single-leg balance tasks. Little is known about dynamic postural control deficits post-ACLR. Objectives To compare dynamic postural control (bilaterally) in persons who have undergone ACLR and healthy control

To determine the incidence of anterior cruciate ligament (ACL) injuries in the general population; the pathology associated with a knee sprain verified by magnetic resonance imaging (MRI); and the agreement between clinical findings and MRI.Materials and methods: Inclusion criterion was an acute rotational trauma to the knee associated with effusion. One hundred and fifty-nine consecutive patients

The discovery of the role of α-synuclein in the pathogenesis of Parkinson's disease (PD) has opened new possibilities for the development of more authentic models of Parkinson's disease. Recombinant adeno-associated virus (AAV) and lentivirus (LV) vectors are efficient tools for expression of genes locally in subsets of neurons in the brain and can be used to express human wild-type or mutated α-s

The neuroprotective effect of the glial cell line-derived neurotrophic factor has been extensively studied in various toxic models of Parkinson's disease. However, it remains unclear whether this neurotrophic factor can protect against the toxicity induced by the aggregation-prone protein α-synuclein. Targeted overexpression of human wild-type α-synuclein in the nigrostriatal system, using adeno

Popular Abstract in Swedish Balansen mellan våra energibehov och den energi som konsumeras är ej längre i jämvikt. Därför är jakten på alternativa energikällor nödvändig. Hållbara energikällor erbjuder ett bra alternativ till fossilbränslen. Bland många typer av hållbara energikällor erbjuder solenergi möjligheten för mer energi än dagens konsumtion. Solceller är de smarta verktyg som omvandlar ljThe balance between our demands of energy and the energy we are consuming is not in equilibrium anymore. Therefore, the search for other energy resources is indispensable. Sustainable energy sources offer the alternative to the fossil fuels. Within many types of sustainable energy sources, solar energy offers more than the total global energy consumption. Solar cells are the smart conversion tools

Most microlevel studies in the social sciences have focused on the impact of different measured variables. While some studies have also dealt with unobserved variation, it has usually only been controlled for to perfect the estimates of the observables. In this article, the authors applied a modified version of a recently developed method designed to quantify the effect of unobserved variation in

Grafts of foetal ventral mesencephalon, used in cell replacement therapy for Parkinson's disease, are known to contain a mix of dopamine neuronal subtypes including the A9 neurons of the substantia nigra and the A10 neurons of the ventral tegmental area. However, the relative importance of these subtypes for functional repair of the brain affected by Parkinson's disease has not been studied thorou

The interaction among various stakeholder organizations in modern crisis response is very similar to negotiation where each organization has its own goal in addition to a common goal. Decision makers in stakeholder organizations most often have to settle for win-win situations to attain higher joint benefit. In such cases willingness to contribute in joint tasks becomes a prerequisite. In our pres

Recent studies in animal models of Parkinson's disease (PD) have provided evidence that dopamine released from spared serotonin afferents can act as a trigger of dyskinetic movements induced by repetitive, low doses of levodopa. Serotonin neurons have the capacity to store and release dopamine synthesized from systemically administered levodopa. However, because of the lack of any autoregulatory f

Background The impact of the prophylactic vaccine against human papillomavirus (HPV) types 6, 11, 16, and 18 (HPV6/11/16/18) on all HPV-associated genital disease was investigated in a population that approximates sexually naive women in that they were "negative to 14 HPV types" and in a mixed population of HPV-exposed and -unexposed women (intention-to-treat group). Methods This analysis studied

OBJECTIVES: the purpose of this study was to assess the predictive accuracy of conventional cardiovascular risk factors for incident heart failure and atrial fibrillation, and the added benefit of multiple biomarkers reflecting diverse pathophysiological pathways. BACKGROUND: heart failure and atrial fibrillation are interrelated cardiac diseases associated with substantial morbidity and mortality

Introduction Many kinds of footwear are used for various purposes in the workplace in Japan. Careful selection of footwear is needed to protect workers from coldness and to keep the performance of workers in cold workplace where employees have to work under -20℃. On the other hand, safety boots with high heat conductivity from foot to outside are needed for the workers in hot environments. But the

Capacity development for disaster risk reduction is an important process to substantially reduce disaster losses, which threaten sustainable development and the achievement of the Millennium Development Goals. This paper presents a theoretical framework with seven elements for capacity development for disaster risk reduction that has been tested in practise with noteworthy results. The seven eleme

I denna uppsats beskrivs en lagändring som skedde 1863 som resulterade i att judar fick rätt att gifta sig med kristna i Sverige. Syftet med uppsatsen är att förstå den bakomliggande kontexten och att sätta lagstiftningsprocessen i ett sammanhang för att därefter jämföra denna med samma process i Danmark. På detta sätt undersöks vilka likheter och vilka skillnader som funnits mellan länderna. För The Enlightenment period brought new freedoms to the Jewish minority, established in Sweden after the Jewish Declaration of 1782. In 1838 the Jewish Declaration was abolished, however, no new regulations regarding intermarriage between Jews and Christians were established, and it remained that way until the legislation of 1863. As a result of the process of emancipation during the Enlightenment pe

Företagsobligationsmarknaden utgör en viktig del av Sveriges kapitalmarknad och har under de senaste åren upplevt en betydande tillväxt. Genom att emittera företagsobligationer har företag möjlighet att inbringa kapital till sin verksamhet, medan investerare erhåller avkastning. En nyckelaktör i denna process är arrangören, som utses av emittenten för att leda projektet. Arrangören spelar en avgörThe corporate bond market is an important part of Sweden's capital market and has experienced significant growth in recent years. By issuing corporate bonds, companies can raise capital for their operations, while investors receive a financial return. A key element in this process is the arranger, who is appointed by the issuer to manage the project. The arranger plays a crucial role, particul