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Fires as collateral or means of war: challenges of environmental peacebuilding in the Kurdistan Region of Iraq

Environmental peacebuilding broadly refers to how sustainable management of natural resources can support prevention, mitigation, and resolution of conflict, as well as recovery after conflict. Shared natural resources constitute a common environmental challenge around which cooperation may be fostered. Environmentally damaging fires in conflict areas have received little attention from the peaceb

Phosphodiesterase 5 and its inhibitors with ischemic heart disease : a Mendelian randomization analysis and a real-world study

BACKGROUND: Accumulating studies reported that several phosphodiesterases (PDEs) inhibitors might have cardiovascular benefits.OBJECTIVES: This study aimed to explore the relationship between genetically-predicted PDEs and ischemia heart disease via drug target Mendelian randomization (MR) approach, and then examine the effect of inhibitors of identified target on the outcomes by using real-world

The Perils of Limited Key Reuse: Adaptive and Parallel Mismatch Attacks with Post-processing Against Kyber

The Module Learning With Errors (MLWE)-based Key Encapsulation Mechanism (KEM) Kyber is NIST's new standard scheme for post-quantum encryption. As a building block, Kyber uses a Chosen Plaintext Attack (CPA)-secure Public Key Encryption (PKE) scheme, referred to as Kyber.CPAPKE. In this paper we study the robustness of Kyber.CPAPKE against key mismatch attacks.We demonstrate that Kyber's security

A combined neural ODE-Bayesian optimization approach to resolve dynamics and estimate parameters for a modified SIR model with immune memory

We propose a novel hybrid approach that integrates Neural Ordinary Differential Equations (NODEs) with Bayesian optimization to address the dynamics and parameter estimation of a modified time-delay-type Susceptible-Infected-Removed (SIR) model incorporating immune memory. This approach leverages a neural network to produce continuous multi-wave infection profiles by learning from both data and th

Diet and lifestyle factors and risk of atherosclerotic cardiovascular disease—a prospective cohort study

Atherosclerotic cardiovascular disease (ACVD) is the leading cause of death worldwide. This study aimed to investigate the association between diet and lifestyle factors, beyond traditional risk factors, and the risk of incident ACVD. The Malmö Diet and Cancer study included 30,446 middle-aged individuals. Baseline examinations including a dietary assessment, questionnaire and interviews, were per

Response to comment on “A global environmental crisis 42,000 years ago”

Our paper about the impacts of the Laschamps Geomagnetic Excursion 42,000 years ago has provoked considerable scientific and public interest, particularly in the so-called Adams Event associated with the initial transition of the magnetic poles. Although we welcome the opportunity to discuss our new ideas, Hawks’ assertions of misrepresentation are especially disappointing given his limited examin

Efficiency Optimization by In-Cycle Closed-Loop Combustion Control

This paper is a comprehensive review of in-cycle closed-loop combustion controllers to achieve higher indicated efficiencies. Closed-loop combustion control reduces the effect of external disturbances and system uncertainties, which permit tighter safety margins and robust operation with a reduced calibration effort. The paper combines different components of previous investigations by the authors

Late mortality among survivors of childhood acute lymphoblastic leukemia diagnosed during 1971–2008 in Denmark, Finland, and Sweden : A population-based cohort study

Objective: Investigate all-cause and cause-specific late mortality after childhood acute lymphoblastic leukemia (ALL) in a population-based Nordic cohort. Methods: From the cancer registries of Denmark, Finland, and Sweden, we identified 3765 five-year survivors of ALL, diagnosed before age 20 during 1971–2008. For each survivor, up to five matched comparison subjects were randomly selected from t

Subgroups of patients with young-onset type 2 diabetes in India reveal insulin deficiency as a major driver

AIM/HYPOTHESIS: Five subgroups were described in European diabetes patients using a data driven machine learning approach on commonly measured variables. We aimed to test the applicability of this phenotyping in Indian individuals with young-onset type 2 diabetes.METHODS: We applied the European-derived centroids to Indian individuals with type 2 diabetes diagnosed before 45 years of age from the

Climate Change and Residential Energy Use in Europe : Assessing Future Energy Demands and Renewable Generation Potentials

In recent years, climate change and the corresponding expected extreme weather conditions have been widelyrecognized as potential problems. The construction industry is taking various actions to achieve sustainabledevelopment, implement energy conservation strategies, and provide climate change mitigation. In addition tomitigation, it is crucial to adapt to climate change, and to investigate the p

Sex differences in off-target binding using tau positron emission tomography

Purpose: Off-target binding in the skull and meninges is observed in some subjects undergoing tau positron emission tomography (PET) and could potentially differ between men and women. In this study we elucidate sex differences in tau off-target binding using three different tau PET tracers. Methods: 541 cognitively unimpaired amyloid-β negative participants underwent tau PET using [18F]flortaucip

A Single-Year Cosmic Ray Event at 5410 BCE Registered in 14C of Tree Rings

The annual 14C data in tree rings is an outstanding proxy for uncovering extreme solar energetic particle (SEP) events in the past. Signatures of extreme SEP events have been reported in 774/775 CE, 992/993 CE, and ∼660 BCE. Here, we report another rapid increase of 14C concentration in tree rings from California, Switzerland, and Finland around 5410 BCE. These 14C data series show a significant i

Epidemiology of firearm injuries in Sweden

Background: Gun violence is a global health problem. Population-based research on firearm-related injuries has been relatively limited considering the burden of disease. The aim of this study was to analyze nationwide epidemiological trends of firearm injuries. Methods: This is a retrospective nationwide epidemiological study including all patients with firearm injuries from the Swedish Trauma Reg

Major Differences in Regional Climate Impact Between High- and Low-Latitude Volcanic Eruptions

Major low-latitude volcanic eruptions cool Earth’s climate, and can lead to a positive phase of the North Atlantic Oscillation (NAO) during winter. However, the question of the climate and circulation impact of Northern Hemisphere high-latitude eruptions has received less attention. Here we show that, contrary to low-latitude eruptions, the response to high-latitude eruptions can be associated wit

Patients present earlier and survival has improved, but pre-ART attrition is high in a six-year HIV cohort data from Ethiopia

BACKGROUND: Previous studies showed higher early mortality rates among patients treated with antiretroviral drugs in settings with limited resources. One of the reasons was late presentation of patients to care. With improved access to HIV services, we expect improvements in disease stage at presentation. Our objective was to assess the effect of improved availability of HIV services on patient pr

Effect of second-trimester sonographic cervical length on the risk of spontaneous preterm delivery in different risk groups : A prospective observational multicenter study

Introduction: The aim of the study is to compare the effect of cervical length measured with transvaginal ultrasound in the second trimester on the risk of spontaneous preterm delivery (PTD) between different risk groups of asymptomatic women with a singleton pregnancy. Material and methods: This is a pre-planned exploratory analysis of the CERVIX study, a prospective blinded multicenter diagnosti

Avoidable deaths in Sweden, 1997–2018: temporal trend and the contribution to the gender gap in life expectancy

Background: Avoidable mortality is considered as a potential indicator of the influences of public health policies and healthcare quality on population health. This study aimed to examine the trend in avoidable mortality and its influence on rising life expectancy (LE) and declining gender gap in LE (GGLE) in Sweden. Methods: We extracted data on causes of death by age, sex, and year from nationa

Energy renovation strategies for office buildings using direct ground cooling systems

Direct ground cooling systems (DGCS) can provide comfort cooling to buildings without the use of any refrigeration-based cooling methods. DGCS is an emerging technology, commonly used for new office buildings in cold climates. This study aims to evaluate the energy-saving possibilities of a DGCS compared to a conventional chiller system for an existing office building. A typical Swedish office bui

The effect of external pressure on intramuscular blood flow at rest and after running

Local blood flow in the thigh was measured with 133Xe clearance technique in eight male distance runners after compression with a foam rubber compress and a standard elastic bandage. Two degrees of compression were tested, and an initial experiment with rested subjects was followed by a similar experiment immediately after running. Maximum compression exerted a cutaneous pressure of 85 (+/- 8) mm