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A critical cell cycle regulatory protein, cyclin A1, has been implicated in the development of acute myeloid leukemia (AML). Here, we have examined the expression and clinical significance of cyclin A1 in childhood acute lymphoblastic leukemia (ALL). Cyclin A1 was highly expressed in lymphoblastic leukemic cell lines and in 22 of 30 ALL patients (73%). Cyclin A1 expression correlated with patient

Atmospheric dispersion represents a relatively overlooked problem in connection with the ultimate quality of ELT images corrected by adaptive optics (AO). The aim of this paper is to evaluate the contribution from atmospheric dispersion to the background level of the point-spread function (PSF). Since proper suppression of this level is important for the prospects for direct exo-planet observation

A selective and sensitive method is presented for biogenic amines (BA) determination. The novelty consists in coupling a highly selective electrochemical biosensor to a weak acid cation-exchange column for online detection of amines. A bienzyme design, based on a recently isolated amine oxidase from grass pea and commercial horseradish peroxidase, was used for the biosensor construction. The enzym

Uppsatsen behandlar begreppet arbetsbrist i bemanningsföretag. För att en arbetsgivare ska kunna säga upp en arbetstagare krävs det saklig grund i form av antingen arbetsbrist eller personliga skäl. Vinstdrivande uthyrningsverksamhet legaliserades i Sverige år 1993, och bemanningsbranschen har sedan dess kommit att bli en naturlig del av den svenska arbetsmarknaden. Branschen bygger på ett trepartThe essay addresses the subject termination of an employment contract with notice due to redundancy. Termination with notice by the employer must be based on objective grounds, which could be either due to redundancy or circumstances related to the employee personally. Profit-making temporary work agencies were legalised in Sweden in 1993 and have since become a natural part of the Swedish labour

Problemformulering: Byggprocessen är idag långsam, kostsam och genererar stora mängder spill och utsläpp. För att kunna möta bostadsbehovet från den snabbt växande befolkningsmängden måste tekniken utvecklas, den måste bli snabbare och mer kostnadseffektiv. Med ny teknik där betongelement tillverkas genom automatiserad och datorstyrd 3D-printning kan eventuellt hela betongbyggnadsprocessen effektiQuestion formulation: The construction process today is slow, costly and generates large amounts of waste and emissions. In order to meet housing needs of the rapidly growing population in a sustainable way, the technology must evolve; it must be faster and more cost-effective. New technology, where concrete is manufactured by automated and computer-controlled 3D-printing, can possibly streamline

The main purpose of this study is to investigate how members of staff at group homes (LSS-bostäder) reason about the service users’ rights to self-determination in everyday life. Additionally, this study aims to investigate how group homes as a place may affect the fulfillment of self-determination rights. The following theories “The theory of Recognition” and ”the Principle of normalization”, the

This thesis aims to explore the meanings behind rural reading rooms (tushushi) in Yunnan Province, PRC. Rural reading rooms are small libraries attached to the village Party compound in Chinese villages; for the past decade 600 000 reading rooms have been established in administrative villages in China, and now benefit more than 1 billion farmers in what is arguably the world’s most important deve

This Thesis examines what possibilities Member States have to impose levies on CO2 emissions from motor vehicles in the light of EU indirect tax legislation and the Eurovignette Directive. In this Thesis, carbon tax on fuel and a CO2 differentiated road toll are studied as levying options. Motor fuel is an excise good to which the harmonised EU excise duty system applies. Accordingly, the questi

This study investigates the potential of large language models (LLMs), such as ChatGPT, to aid venture capitalists in the screening of startups that maximize sustainability impact. To determine the scope that maximizes impact for venture capitalists' and to identify effective screening criteria, the study utilized theoretical research and interviews. The thesis suggests that the ideal investme

An electrochemical biosensor based on ZnO nanorods for potentiometric cholesterol determination is proposed. Hexagon-shaped ZnO nanorods were directly grown on a silver wire having a diameter of 250 mu m using low temperature aqueous chemical approach that produced ZnO nanorods with a diameter of 125250 nm and a length of similar to 1 mu m. Cholesterol oxidase (ChOx) was immobilized by a physical

Abstract in Uncoded languages Inspiracija za rad i problem(i) koji se radom oslovljava(ju): Ranija istraživanja poslijeratnih društava istakla su strukturalno nasilje sa pratećim procesima pomirenja. Autori su istakli važnost priča, ali se nisu fokusirali na priče o pomirenju niti su analizirali uvjete za pomirenje u poslijeratnim intervjuima. Ciljevi rada (naučni i/ili društveni): Cilj članka je Reason(s) for writing and research problem(s): Previous research on post-war society emphasized structural violence with subsequent reconciliation processes. Aims of the paper (scientific and/or social): Researchers have focused on the importance of narratives, but they have neither highlighted narratives about reconciliation nor analyzed conditions for reconciliation in post-war interviews. One a

Background: We aimed to study the long-term effect of smoking on coronary atherosclerosis progression at the segmental level. Methods: Angiographic data (1989-2017) on current, former, and nonsmokers were collected from the Swedish Coronary Angiography and Angioplasty Registry. The Western Denmark Heart Registry was used to validate the results. Patients with clinically indicated angiography with

Background: Multiple clinical practice guidelines and head computed tomography decision rules exist for emergency department (ED) triage of children with traumatic brain injury (TBI). These vary in structure, aim, target cohort, and outcomes, yet are used clinically in similar populations. We compared important clinical and practical characteristics of all major guidelines in a large, real-world p

This paper describes preliminary results from the test-retest of the NAME 1.0. Four scales were tested: Mobility-related participation frequency; Mobility ease/difficulty; Mobility dependence; Extent of assistance in mobility. The test was conducted in the five Nordic countries. In all 147 mobility device users took part in the study, mean age 60 years (range 19 - 93). Each participant was intervi