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BACKGROUND AND AIM: Warming temperature promotes bacterial growth while extreme precipitation enhances fecal-oral route of exposures to these pathogens, particularly in resource limited settings, increasing burden of diarrheal diseases. Given climate change related increases in frequency of extreme events, there is a pressing need to develop meaningful early warning system with adequate lead time
BACKGROUND: ATOR-1017 (evunzekibart) is a human agonistic immunoglobulin G4 antibody targeting the costimulatory receptor 4-1BB (CD137). ATOR-1017 activates T cells and natural killer cells in the tumor environment, leading to immune-mediated tumor cell death.METHODS: In this first-in-human, multicenter, phase I study, ATOR-1017 was administered intravenously every 21 days as a monotherapy to pati
Scanning coherent X-ray microscopy (ptychography) has gained considerable interest during the last decade since the performance of this indirect imaging technique does not necessarily rely on the quality of the X-ray optics and, in principle, can achieve highest spatial resolution in X-ray imaging. The method can be easily extended to 3D by adding standard tomographic reconstruction schemes. Howev
"Storsjöodjuret”, eller “The Great Lake Monster”, är ett undflyende fenomen i sjön Storsjön, belägen i landskapet Jämtland i norra Sverige. Denna avhandling i ämnet humanekologi undersöker hur det sammankopplingar av det sociala, det kulturella, det historiska och det lokala påverkar formandet av detta svenska kryptid, eller “dolda djur”. Syftet med studien är att visa hur detta vetenskapligt ännuStorsjöodjuret, or The Great Lake Monster, is an elusive phenomenon in lake Storsjön, situated in the province of Jämtland in Northern Sweden. This dissertation in Human Ecology investigates how the intricate web of the social, the cultural, the historical, and the local influence the shaping of this Swedish cryptid, or “hidden animal”. The purpose of the study is to demonstrate how this scientifi
Det första skedet när ett byggnadsverk ska uppföras är det konceptuella designskedet, det är här de första besluten om utformningen av byggnadsverket görs. I det traditionella arbetsflödet utformas byggnadsverket först i ett ritprogram, sedan används ett annat datorverktyg för att verifiera att det utformade byggnadsverket kan hantera de krafter som uppstår, t.ex. vind, egentyngd osv. Detta arbeteBefore a new structure can be built, it must be designed. This design phase is a very important step in the building process. The total cost of the structure and its structural performance are largely dependent on the structural design process. The impact of decisions on the design process is initially high and declines as the design matures. However, few computational tools are available for the
It is established that the glomerular filter sieves macromolecules based on their size, shape, and charge. Anionic proteins are thus retarded compared with their neutral or cationic counterparts. However, recent studies have indicated that charge effects are small, or even "anomalous," for polysaccharides. We therefore investigated the impact of charge on the glomerular permeability to polysacchar
Popular Abstract in Swedish Hypertoni (högt blodtryck) och typ 2 diabetes (åldersdiabetes) är vanligt förekommande sjukdomar i Sverige. Ingen av sjukdomarna ger inledningsvis några särskilda symptom. Det är dock viktigt att upptäcka och behandla dessa tillstånd, eftersom de ger upphov till ökad sjukdom och till överdödlighet i hjärt-kärlsjukdomar såsom hjärtinfarkt, hjärtsvikt och slaganfall. FöreTo examine cardiovascular disease risk factors, control of hypertension and survival in patients with hypertension treated in primary care, patients with hypertension and/or type 2 diabetes were surveyed for cardiovascular disease risk factors and treatment 1992-1993. For reference, a random population sample from the same community was surveyed 1993-1994. During 1998, antihypertensive prescriptio
The recent phenomenon that has become known as the European refugee crisis is, in reality, a global problem. Accordingly, issues regarding refugee integration have become a central debate topic worldwide. In this paper, we examine how refugees use information and communication technology (ICT) in different regions across the world to understand how ICT supports their desperate journey to safety, t
PURPOSE: To examine sex differences in health-related quality of life (HRQoL) among patients surgically treated for renal cell carcinoma (RCC) in Sweden, utilizing data from the National Swedish Kidney Cancer Register (NSKCR).METHODS: In this study of 4658 surgically treated RCC patients, data on HRQoL, clinical, demographic, and socioeconomic characteristics were retrieved from the NSKCR for pati
In June 2024, the community of Roxborough Park, Colorado conducted a wildfire evacuation exercise (or drill for short) that was observed by a team of researchers. This collaborative effort involved residents, community organizers, first responders, emergency managers, and researchers. The drill aimed to test and refine evacuation protocols, communication strategies, and coordination among various
eq11-30March 14.30 EQ11: Faculty self-reflection Faculty of Fine and Performing Arts Malmö Academy of Music (MAM) Malmö Art Academy (MAA) Malmö Theatre Academy (MTA) 30 March 2011 Faculty of Fine and Performing Arts 2 Contents Part 1: Area I. Research-based education 3 Area II. Innovation 9 Area III. Outcomes 17 Area IV. Alignment 25 Area V. Management 34 Area VI. Scholarship 48 Area VII. Internat
https://www.konstnarliga.lu.se/sites/konstnarliga.lu.se/files/eq11_fine_perf_arts.pdf - 2026-05-22
We study inhomogeneous random graphs in the subcritical case. Among other results, we derive an exact formula for the size of the largest connected component scaled by logn, with n being the size of the graph. This generalizes a result for the "rank-1 case". We also investigate branching processes associated with these graphs. In particular, we discover that the same well-known equation for the su
The Kruppel-like protein ZNF224 is a co-factor of the Wilms' tumor 1 protein, WT1. We have previously shown that ZNF224 exerts a specific proapoptotic role in chronic myelogenous leukemia (CML) K562 cells and contributes to cytosine arabinoside-induced apoptosis, by modulating WT1-dependent transcription of apoptotic genes. Here we demonstrate that ZNF224 gene expression is down-regulated both in
