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Methodology for fast development of digital solutions in integrated continuous downstream processing

The methodology for production of biologics is going through a paradigm shift from batch-wise operation to continuous production. Lot of efforts are focused on integration, intensification, and continuous operation for decreased foot-print, material, equipment, and increased productivity and product quality. These integrated continuous processes with on-line analytics become complex processes, whi

Conceptual and Practical Strategy Work to Promote Ergonomics/Human Factors in Sweden

This paper describes the results of the conceptual and practical strategy work performed by the Swedish Ergonomics and Human Factors Society (EHSS) today. The rationale of EHSS is to strengthen the quality of ergonomics/human factors knowledge and practice in Sweden and form a multidisciplinary platform across disciplines and professions for collaboration and for knowledge sharing. EHSS gathers ab

Low-dose oral ketamine as a procedural analgesia in pediatric cancer patients undergoing bone marrow aspirations at a resource-limited cancer hospital in India

Aim: Many pediatric cancer patients undergo repeated bone marrow aspirations (BMAs) for diagnostic and treatment evaluation purposes. Full anesthesia is the standard of care during this procedure in high-income countries. At hospitals with low resources in low/middle-income countries many children undergo these painful procedures without sufficient pain relief. This study aimed to evaluate the use

The Subscriptions to Mark’s Gospel and History of Reception

Den här artikeln granskar subskriptionerne på Markusevangeliet i 157 grekiska handskrifter, och noterar deras gradvisa utveckling från att vara identisk med titeln i den tidigaste fasen till att bli mer och mer utarbetad och betydelsefull för tolkningshistorien. Tidigt, vilket återspeglas i titeln, förknippades det andra evangeliet med Markus, känd för att vara Petrus lärjunge och tolk. Under det This article surveys the subscriptions to the Gospel of Mark in 157 Greek manuscripts, noting their gradual development from being identical to the title in the earliest phase to becoming more and more elaborate and significant for the history of interpretation. Early on, as reflected in the title, the Second Gospel was associated with Mark, known to be Peter’s disciple and interpreter. In the fou

Intracoronary Imaging of Proximal Coronary Artery Lesions – A Nationwide Lesion-Level Analysis From SCAAR

Background: Current evidence suggests that use of intracoronary imaging during percutaneous coronary intervention (PCI) of the left main coronary artery (LMCA) reduces mortality. However, there is a scarcity of data on the overall role of intracoronary imaging, particularly in other non-LMCA proximal coronary artery lesions. We aimed to investigate the association of use of intracoronary imaging o

Protocol for the Process Evaluation of the Online Remote Behavioural Intervention for Tics (ORBIT) randomized controlled trial for children and young people

Background: Process evaluations are an important component in the interpretation and understanding of outcomes in trials. The Online Remote Behavioural Intervention for Tics (ORBIT) study is a randomized controlled trial evaluating the effectiveness of an Internet-delivered behavioural intervention (called BIP TIC) compared to an Internet-delivered education programme aimed at children and young p

Integrated system for interstitial photodynamic therapy

A novel photodynamic therapy system based on interstitial illumination using multiple fibres is under development. The aim with this system is to enable treatment of large tumour volumes and also to utilise real-time measurements to allow on-line dosimetry. Important dosimetric parameters to measure are light fluence rate, sensitizer fluorescence intensity and local blood oxygenation. A constructi