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Background: Clinical egg allergy is a common food allergy. Current management relies upon strict allergen avoidance. Oral immunotherapy might be an optional treatment, through desensitization to egg allergen. Objectives: To determine the efficacy and safety of oral and sublingual immunotherapy in children and adults with immunoglobulin E (IgE)-mediated egg allergy as compared to a placebo treatmen
The aim was to evaluate volume, diffusion, and perfusion metrics for better presurgical differentiation between high-grade gliomas (HGG), low-grade gliomas (LGG), and metastases (MET). For this retrospective study, 43 patients with histologically verified intracranial HGG (n = 18), LGG (n = 10), and MET (n = 15) were chosen. Preoperative magnetic resonance data included pre- and post-gadolinium co
Background: Attention deficit hyperactivity disorder (ADHD) in children is associated with hyperactivity and impulsivity, attention problems, and difficulties with social interactions. Pharmacological treatment may alleviate the symptoms of ADHD but this rarely solves difficulties with social interactions. Children with ADHD may benefit from interventions designed to improve their social skills.We
Efter att ha dominerat angloamerikansk filosofi under 1800-talets sista decennier kom idealismen att förlora sin ställning efter sekelskiftet, då övergången från viktorianska till modernistiska ideal, snabba sociala förändringar, ökad sekularisering och naturvetenskapens dominans tycktes kräva nytt filosofiskt tänkande. Vid andra världskrigets utbrott var idealismen utdöd och ersatt av den analytiAfter having dominated philosophical thought in Britain and the United States during the end of the nineteenth century, idealism was in steady decline by the outbreak of World War I. Its ideas and ideals seemed unsuited to face the transition from Victorianism to modernism and the rapid social changes of the post-war era. Its Anglo-American proponents—who were often liberals—were accused of indire
Background: Middle Eastern immigrants represent a growing population in Sweden today. This group are at higher risk for type 2 diabetes than the native population, but are also shown to exhibit unique properties; despite an abundance in traditional cardiometabolic risk factors such as obesity, dearranged blood lipids and diminished physical acitivity, this group seem to exhibit lower blood pressur
Background: According to the “brain-reserve hypothesis” in Alzheimer’s disease (AD), patients with more years of education are expected to have higher cognitive status during adulthood. Hence, they might have a relatively larger burden of AD pathology and a more advanced level of the disease when dementia is clinically evident. Higher educated people would also be expected to perform better on sta
Agriculture is key to sustainable development globally – particularly incountries where agriculture both accounts for most of the land use andprovides a livelihood for most of the population. We map out a collaborativeresearch agenda aimed at tackling the urgent but poorly understood issue ofthe role of farmer organisations in overcoming political barriers tosustainable and inclusive agricultural
We performed a large nested case-control study within the Finnish and Icelandic maternity cohorts to verify/falsify the association of maternal EBV infection with an increased risk of acute lymphoblastic leukemia (ALL) in the offspring found in previous studies. All hematologic malignancies diagnosed among children born during 1983 to 2006 in Finland and 1997 to 2005 in Iceland were identified thr
Importance: Patients who survive severe intracerebral hemorrhage (ICH) and intraventricular hemorrhage (IVH) typically have poor functional outcome in the short term and understanding of future recovery is limited. Objective: To describe 1-year recovery trajectories among ICH and IVH survivors with initial severe disability and assess the association of hospital events with long-term recovery. Des
Significant efforts are ongoing to develop refined differentiation protocols to generate midbrain dopamine (DA) neurons from pluripotent stem cells (PSCs) for application in disease modeling, diagnostics, drug screening, and cell-based therapies for Parkinson's Disease (PD). An increased understanding of the timing and molecular mechanisms promoting the generation of distinct subtypes of human mid
Background: Free oxygen radicals have been implicated in the pathogenesis of bronchopulmonary dysplasia (BPD) in preterm infants. Superoxide dismutase (SOD) is a naturally occurring enzyme which provides a defense against such oxidant injury. Providing supplementary SOD has been tested in clinical trials to prevent BPD in preterm infants. Objectives: To determine the efficacy and safety of SOD in
Klimatpåverkan och dess effekter är ett högaktuellt ämne för alla branscher och industrier särskilt för bygg- och fastighetsbranschen som år 2021 stod för 22% av utsläppen av växthusgaser i Sverige (Boverket, 2024a). Visserligen har det skett en minskning av utsläppen för branschen sedan 2008 men behovet av att bygga nya bostäder är stort samtidigt som byggkostnaderna i Sverige blir dyrare och dyrThe impact of climate change and its effects is a current topic for all industries, especially the construction and real estate sectors, which accounted for 22% of greenhouse gas emissions in Swedenin 2021 (Boverket, 2024a). Although emissions from the sector have decreased since 2008, the need for new housing is significant, and construction costs in Sweden are rising more and more every year. T
Augustenborg is suburb city in Malmö south of Sweden. The climate is temperate with occasional snow during the winter. Open storm water is applied in Augustenborg since late 1990s and the storm water is disconnected from the combined sewer system in order to give the area a lift up value and to solve the flooding problems in basements after heavy rainfall events. The new open system consists of po
Barnets bästa är en rättighet i artikel 3.1 i barnkonventionen. Svensk rätt fast-slår barnets bästa i 6 kap. 2 a § FB. Bestämmelsen uppdaterades senast den 1 januari 2025. Gällande rätt visar att bestämmelsen uppdaterades för att framhålla att risken för att barnet utsätts för våld eller annan kränkande behandling alltid ska ha större betydelse än barnets behov av en god och nära relation till sinThe best interests of the child are a right stipulated in Article 3.1 of the Convention on the Rights of the Child. In Swedish law, the best interests of the child constitute a guiding principle laid down in Chapter 6, Section 2 a of the Children and Parents Code (FB). The principle was last amended on 1 January 2025. An examination of the applicable law shows that the purpose of the amendment was
The Energy Performance of Buildings Directive (EPBD) amendment of 2024 is a major tool in the EU’s environmental aim of net-zero carbon emissions for the building stock by 2050. The overall goal is to improve energy performance, boost renovation rates, reduce energy bills and support decarbonisation of the building stock. This thesis investigates through a literature review, what the 2024 recast o
STUDY QUESTIONDoes endometriosis and/or adenomyosis, diagnosed using the International Deep Endometriosis Analysis (IDEA) group and the Morphological Uterus Sonographic Assessment (MUSA) group revised definitions, impact cumulative live birth rates (CLBR) after three consecutive IVF or ICSI treatments?SUMMARY ANSWERWomen with endometriosis and/or adenomyosis, as diagnosed using transvaginal ultras
Background: Neuroimaging with magnetic resonance imaging (MRI) may assist clinicians in evaluating brain injury and optimising care in comatose adults resuscitated after out-of-hospital cardiac arrest (OHCA). However, contemporary international data on its use are lacking. Aim: The primary aim was to compare the patient characteristics, early postresuscitation care, and neurological outcomes of pa
