Modulation of innate immunity by type 2 inflammation precision targeting therapeutics: T2 cytokines as modulators of human bronchial epithelial cells.
Airway epithelium, formed by epithelial cells lining human airways, is a critical barrier against inhaled allergens, viruses, and pollutants. Beyond being a physical barrier, it functions as a first-line defense by secreting alarmins, inflammatory cytokines, and chemokines, thereby activating other immune cells. In respiratory diseases like asthma and chronic obstructive pulmonary disease (COPD),
