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EndoS from Streptococcus pyogenes efficiently hydrolyzes the functionally important and conserved N-linked glycan of IgG in human blood. Repeated i.v. administration of EndoS in rabbits completely hydrolyzes the glycans of the whole IgG pool, despite the generation of anti-EndoS antibodies. EndoS administration had no apparent effects on the health of the animals. EndoS hydrolysis of the IgG glyca
Group B Streptococcus (GBS) is a leading cause of invasive bacterial infections in human newborns. A key GBS virulence factor is its capsular polysaccharide (CPS), displaying terminal sialic acid (Sia) residues which block deposition and activation of complement on the bacterial surface. We recently demonstrated that GBS Sia can bind human CD33-related Sia-recognizing immunoglobulin (Ig) superfami
Protein ADP-ribosylation is a reversible post-translational modification that regulates important cellular functions. The identification of modified proteins has proven challenging and has mainly been achieved via enrichment methodologies. Random mutagenesis was used here to develop an engineered Af1521 ADP-ribose binding macro domain protein with 1000-fold increased affinity towards ADP-ribose. T
Lymphocytes from human peripheral blood were separated by Countercurrent distribution (CCD) in a charged aqueous two-phase system composed of Dextran T 500 and polyethylene glycol 6000. Maximal responses to the T-cell mitogens phytohemagglutinin and concanavalin A were detected in a part of the distribution corresponding to the area where the highest percentage of E rosetting cells were seen. Anti
Regular prophylactic treatment with factor VIII (FVIII) and factor IX (FIX) concentrates in hemophilia A and B, respectively, is introduced in early infancy and has resulted in dramatic improvement of the conditions. Recombinant FVIII and FIX concentrates have been available for > 25 years and have been modified and refined through the years; however, unfortunately frequent intravenous administrat
Background: A unique feature of alveolar mast cells is their low high-affinity IgE receptor (FcεRI) expression. Recent discoveries in uncontrolled asthma suggest that the appearance of FcεRI-expressing alveolar mast cells may be a novel disease-specific feature of allergic asthma. This study investigates whether increased FcεRI-expressing alveolar mast cells are present in patients with mild aller
Corruption is indisputably an immense obstacle for many developing countries in their endeavor to prosper economically. Zambia, a peaceful, politically stable democracy is still facing many of the problems connected with corruption. Corruption has so far mostly been measured on a state-level, but in our thesis we narrow the field of investigation down to the ministry-level. We use questionnaires t
This review compares the methodology of published clinical studies investigating the extended-half-life (EHL) factor VIII (FVIII) products, rFVIIIFc (efmoroctocog alfa, Elocta®/Eloctate®), BAY 94-9027 (damoctocog alfa pegol, Jivi®), BAX 855 (rurioctocog alfa pegol, Adynovate®) and N8-GP (turoctocog alfa pegol, Esperoct®) including the phase 2/3 studies, A-LONG (NCT01181128), PROTECT VIII (NCT01580
Ett smartare Sverige Sacos kongress 2025 Verksamhets rapport januari–juni 2025 1/14 Uppföljning av verksamheten första halvåret 2025 Sammanfattning Under det första halvåret 2025 har Saco bedrivit aktivt påverkansarbete och mediegenomslaget har varit starkt. Därutöver har nya aktiviteter genomförts för att ytterligare stärka samverkan och stöd inom federationen. Rapporter, remissvar, debattartikl
PROTO KOLL 6:2018 Dnr STYR 2018/1350 LUN DS UNIVERSITET Institutionen for psykologi ledningsgruppen for psykologprogrammet Sammantradesdatum 2018-09-12 Niirvarande ledamoter Martin Wolgast Kristian Almquist Maja Bengtsson Strath Bengt Brattgard Daiva Daukantaite Gorana Holm Maria Holmqvist Tomas Jungert Jens Knutsson Erik Lundin Berti( Persson Susanna Vestberg Margit Wangby Lundh Anita Lennerstedt
https://www.psy.lu.se/sites/psy.lu.se/files/psp_180912_nr6_protokoll_mu.pdf - 2026-06-04
Master’s Dissertation Structural Mechanics JIMMY PERSSON Report TV SM -5181 JIM M Y PERSSO N N U M ER IC A L A N A LY SIS O F C O M PR ESSIO N PER PEN D IC U LA R TO TH E G R A IN IN G LU LA M B EA M S W ITH A N D W ITH O U T R EIN FO R C EM EN T NUMERICAL ANALYSIS OF COMPRESSION PERPENDICULAR TO THE GRAIN IN GLULAM BEAMS WITH AND WITHOUT REINFORCEMENT Detta är en tom sida! Copyright © 2011 by Str
https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm5000/web5181.pdf - 2026-06-01
Recent studies have highlighted how building resilience to ‘shrinking’ episodes, as opposed to increasing growth rates, appears to be the missing piece of the puzzle when it comes to between-country income convergence. All economies seem to be able to grow, but few countries have been able to drastically improve their shrinking patterns, which has underpinned the divergence often argued in literat
Studiens syfte var att undersöka hbtq+-personers upplevelser och hantering av minoritetsstress i nära relationer samt upplevda konsekvenser på hälsan och de nära relationerna. Detta gjordes genom semistrukturerade intervjuer med tio personer, som bröt mot cis- och/eller heteronormen. En tematisk analys av berättelserna utmynnade i tre huvudteman: Omvänd skuld- och ansvarsfördelning, Två sidor av mThe aim of this study was to explore how LGBTQ+ people experience and cope with minority stress in their close relationships, how minority stress affects the relationships and what health implications might come from it. Ten semi-structured interviews were conducted with LGBTQ+ individuals. A thematic analysis of the stories resulted in three main themes: Reverse guilt and liability, Two sides of
Modulenthus is a company in the wood house industry that builds houses in volumes. Volume building means that Modulenthus builds predecorated house volumes in a factory and transports these to the building sites where they are being put together to complete detached houses. The purpose of these Master Thesis is that, on the basis of Modulenthus conditions and wishes, evaluate a possible using of a
