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High-order surface tension VOF-model for 3D bubble flows with high density ratio

An improved Volume of Fluid (VOF) method is presented which is applicable to high density ratio 3D flows for a large range of bubble Reynolds number (Re). The method is based on the Navier-Stokes equations for incompressible multi-phase flows which are discretized on a Cartesian staggered grid. The multi-grid technique together with the pressure-velocity coupling scheme for multi-phase flows have

Summary of the recommendations on sexual dysfunctions in men

Introduction. There are few published guidelines for the management of sexual dysfunctions in men and women, despite the prevalence and lack of attention to these problems. Disorders of sexual function in men include erectile dysfunction, orgasm/ejaculation disorders, priapism, and Peyronie's disease. Aim. To provide evidence-based and expert-opinion consensus guidelines for the clinical managemen

Dynamic Solid Oxide Fuel Cell Modelling for Non-steady State Simulation of System Applications

Most of the world's energy generation is based on fossil fuels such as coal and oil, which already today but even more in the future, will cause various problems. One issue is their limited availability, which stands in conflict to the increasing global energy consumption. Another problem is the carbon dioxide generation caused by burning fossil fuels for energy production, and is thought to be on

A combination of magnetic permeability detection with nanometer-scaled superparamagnetic tracer and its application for one-step detection of human urinary albumin in undiluted urine

A rapid (6.5 min) and simple one-step magnetic immunoassay (MIA) has been developed for analysis of human urinary albumin in near patient settings. Polyclonal rabbit anti-human albumin was used as a capture antibody and monoclonal mouse anti-human albumin as a detection antibody in a two-site immunometric assay requiring no additional washing procedures. The polyclonal anti-human albumin was conju

Traces of copper ions deplete glutathione in human hepatoma cell cultures with low cysteine content

Background: Cell death induced by intracellutar glutathione depletion has been reported to be dependent on the presence of trace amounts of extracellular copper ions. Since little is known about the relationship between glutathione depletion and copper homeostasis, we have in the present study further investigated the role of low amounts of copper ions in glutathione depletion. Methods: Glutathion

Kluskap - as local culture hero and global green warrior: Different narrative contexts for the Canadian Mi’kmaq culture hero

The first stories about Kluskap, the culture hero of the Mi’kmaq in eastern Canada, were written down at the end of the 19th century. The romantic epoch and the environmental failures of industrialism had generated a growing interest for the “Indian”, who seemed to inherit the continent’s authentic “poetry of the Volk” and harbour deep wisdom about nature. The first written literature about Kluska

Improved modeling of heat transfer in dropwise condensation

Dropwise condensation has drawn significant attention due to its efficient heat transfer performance compared to filmwise condensation. In this paper, typical experimental data for dropwise condensation on smooth hydrophobic surfaces were collected as well as the typical available heat transfer models. The comparisons between the prediction results and the experimental data indicated that the exis

Genetic parameters for noncoagulating milk, milk coagulation properties, and detailed milk composition in Swedish Red Dairy Cattle

The rennet-induced coagulation ability of milk is important in cheese production. For Swedish Red Dairy Cattle (RDC), this ability is reduced because of a high prevalence of noncoagulating (NC) milk. In this study, we simultaneously combined genetic parameters for NC milk, milk coagulation properties, milk composition, physical traits, and milk protein composition. Our aim was to estimate heritabi

BCG scarring and improved child survival : a combined analysis of studies of BCG scarring

Bacillus Calmette–Guérin (BCG) vaccine against tuberculosis (TB) is recommended given at birth in TB-endemic areas. Currently, BCG vaccination programmes use “BCG vaccination coverage by 12 months of age” as the performance indicator. Previous studies suggest that BCG-vaccinated children, who develop a scar, have better overall survival compared with BCG-vaccinated children, who do not develop a s

Commercial albumin solution enhances endotoxin-induced vasoplegia and inflammation

BACKGROUND: The Gram-negative bacterium Escherichia coli, commonly involved in severe sepsis and septic shock, shed endotoxin that upon detection by the host triggers an inflammatory cascade. Efficiency of albumin solutions to restore hypovolemia during sepsis has been debated. To aid identification of subgroups of sepsis patients that may respond positively or negatively to treatment with albumin

Fetal programming of semen quality (Fepos) cohort – a dnbc male-offspring cohort

Background: Prenatal exposures may contribute to male infertility in adult life, but large-scale epidemiological evidence is still lacking. The Fetal Programming of Semen quality (FEPOS) cohort was founded to provide means to examine if fetal exposures can interfere with fetal reproductive development and ultimately lead to reduced semen quality and reproductive hormone imbalances in young adult m

Storage and handling of pretreated lignocellulose affects the redox chemistry during subsequent enzymatic saccharification

The decomposition of lignocellulose in nature, as well as when used as feedstock in industrial settings, takes place in a dynamic system of biotic and abiotic reactions. In the present study, the impact of abiotic reactions during the storage of pretreated lignocellulose on the efficiency of subsequent saccharification was investigated. Abiotic decarboxylation was higher in steam-pretreated wheat

Diagnosing colorectal cancer in primary care : cohort study in Sweden of qualitative faecal immunochemical tests, haemoglobin levels, and platelet counts

BACKGROUND: Colorectal cancer (CRC) diagnostics are challenging in primary care and reliable diagnostic aids are desired. Qualitative faecal immunochemical tests (FITs) have been used for suspected CRC in Sweden since the mid-2000s, but evidence regarding their effectiveness is scarce. Anaemia and thrombocytosis are both associated with CRC. AIM: To evaluate the usefulness of qualitative FITs requ

Editor's Choice – Recommendations for Registry Data Collection for Revascularisations of Acute Limb Ischaemia : A Delphi Consensus from the International Consortium of Vascular Registries

Objective: To develop a minimum core data set for evaluation of acute limb ischaemia (ALI) revascularisation treatment and outcomes that would enable collaboration among international registries. Methods: A modified Delphi approach was used to achieve consensus among international multidisciplinary vascular specialists and registry members of the International Consortium of Vascular Registries (IC

Methods to improve quality of life, beyond medicines. Position statement of the European Academy of Dermatology and Venereology Task Force on Quality of Life and Patient Oriented Outcomes

The pharmaceutical approach to skin disease has been hugely successful, but despite effective drugs being available and used, there are still vast numbers of people who continue to have some level of persisting skin disease and continue to experience quality of life (QoL) impairment. So the question that needs to be answered, while we await further advances in our drug-based armamentarium, is how

Car free urban districts – Interactions between measures, implementation and experience

Cities and car traffic does not always fit well together. Apart from the well-knownenvironmental problems associated with traffic congestion (e.g. air pollution and noise,climate change and global warming), there are also negative local effects in the form ofincreased risk of traffic accidents, abuse of key resources (energy and time), gender issues interms of accessibility, security and power ove

Feasibility, safety and patient perceptions of exercise-based cardiac telerehabilitation in a multicentre real-world setting after myocardial infarction—the remote exercise SWEDEHEART study

Aims Cardiac telerehabilitation addresses common barriers for attendance at exercise-based cardiac rehabilitation (EBCR). Pragmatic real-world studies are however lacking, limiting generalizability of available evidence. We aimed to evaluate feasibility, safety, and patient perceptions of remotely delivered EBCR in a multicentre clinical practice setting after myocardial infarction (MI). Methods a