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Dopamine and serotonin are two major monoamine neurotransmitters associated with Parkinson's disease (PD), but their spatial distribution and relationship to underlying functional brain architecture are not fully understood. We assessed 30 patients with PD at baseline using structural MRI, resting-state functional MRI (rs-fMRI), 11C-PE2I and 11C-DASB PET, along with comprehensive clinical evaluati

Popular Abstract in Swedish Talet om det mångkulturella i skolan och samhället: En analys av diskurser om det mångkulturella inom utbildning och politik åren 1973-2006 Det svenska samhället har under de senaste tre decennierna påverkats av debatter, rapporteringar och diskussioner om det mångkulturella samhället. Frågan om hur man ska handskas med ?det mångkulturella? har uppfattats och beskrivitThe debate on "multicultural issues" has had a considerable impact on society, and in Sweden, dealing with such issues has been described and defined as a major problem. The aim of the present thesis is to analyse the various contents of discourses on multicultural issues that have influenced education and policy documents during the period 1973-2006. On several occasions, the Swedish government h

The HILAS (Human Integration in the Life-cycle of Aviation Systems) project is a large, integrated European project which aims to improve safety in the civil air transport sector through the integration of human factors across the life-cycle, while simultaneously generating improved operational efficiencies. The Knowledge Integration strand plays an active role in ensuring that integration takes p

Vitamin D (25OHD) is essential for maintaining calcium homeostasis and inadequate levels have been associated with negative musculoskeletal as well as extraskeletal effects. Individuals at especially high risk of developing hypovitaminosis D are the elderly. The aim of this thesis was to investigate the association between 25OHD insufficiency (25OHD <50 nmol/L) and fractures, frailty and mortality

Klimatförändringar är en av dagens stora utmaningar; en utmaning med betydande konsekvenser som kommer att påverka alla länder på olika sätt om vi inte kan komma överens om ett sätt att motverka den globala uppvärmningen genom att stabilisera utsläppen av växthusgaser. Ett globalt problem kräver internationell respons, men den internationella klimat-regimen har misslyckats med att leverera tillräcClimate change is one of today’s major challenges; a challenge with significant consequences that will affect all countries in different ways if a way to combat global warming by stabilizing greenhouse gas emissions cannot be agreed on. A global problem calls for an international response; however, the international climate regime has failed to deliver adequate results. Currently, states represent

In the effort of modelling the global distribution 7Be, 210Pb and 210Po in surface air, the results from exploration of radioactivity exploration from the Arctic to the Antarctic during 1980 to 1996 are compiled with the results reported by other authors. Partial least square regression modelling PLS-regression, predict missing 7Be, 210Pb and 210Po values of air concentration or annual deposition.

Background: Supply Chain Management is receiving increased attention as companies are trying to remain competitive in a global and challenging environment. An important topic to consider when managing the supply chain is inventory control. Companies today have enormous investments in inventories, which means that there are potential improvements regarding tied up capital in raw materials, work-in-

The right to damage in antitrust cases within the European Community arises from the case Francovich decided by the ECJ. The case established that the individual's right to compensation could be based on Community law. The case also established that the national courts are required to apply the right to compensation regardless of the position of the national law. The first case to follow the p

Energi och klimatpåverkan är ständigt aktuellt i dagens samhälle. För att motverka den globala uppvärmningen har EU tagit fram klimatmål där bland annat energianvändningen ska minska med 20 % mot 1990 års nivåer år 2020. En stor andel av energianvändningen orsakas i Sverige idag av bygg- och fastighetsbranschen där byggnadsbeståndet står för ca 30 % av energianvändningen. För att klara EU:s klimEnergy use and climate impact are important topics in today’s society. To combat global warming, the EU has set a goal framework with a 20 % reduction target until 2020 for domestic energy use compared to 1990. Today, the building sector in Sweden accounts for 30 % of the domestic energy use. To achieve the goals for energy and climate set by the EU, changes are required. The Swedish parliament ha

Popular Abstract in Swedish Kvinnor känner till att det är riskabelt att röka när de blir gravida. Trots detta så slutar bara omkring hälften i Sverige och var tredje kvinna i många andra länder att röka när de blir gravida. Syftet i den här avhandlingen har varit att studera varför det är så svårt för gravida kvinnor att sluta röka. Problemområdet har studerats med olika utgångspunkter; gravida kThe aim of this thesis has been to increase understanding on the process of smoking cessation during pregnancy from the perspective of learning. The smoking pattern before and after pregnancy related to health, Sense of Coherence (SOC) and social issues was studied among all pregnant women in south-east Skåne during the period March 1994 to August 1995. They were asked to fill in a questionnaire d

Square-wave (SQW) ultraviolet-B (UV-B: 280–315 nm) radiation supplementation systems continue to be used in outdoor experimental locations due to the economically restrictive installation and maintenance costs, and technical expertise required to effectively operate more advanced modulated (MOD) delivery systems. However, continued yet contentious criticisms of SQW delivery systems risk creating p

Background: Cognitive impairment is common in Parkinson’s disease (PD), but care needs and resource use for those with significant cognitive impairment are not well established. Methods: 675 participants with PD from the international Care of Late-Stage Parkinsonism (CLaSP) study were grouped into those without (n = 333, 49%) and with cognitive impairment (MMSE < 24/30 or diagnosis of dementia or

Background: Continuous advancements in interventional and diagnostic radiological techniques are mandatory to meet the increasing demands of patients and health care professionals. This thesis aims to contribute to the development of more effective interventional and diagnostic radiological methods for pelvic diseases. Ultimately, these advancements can lead to improved patient outcomes, optimised

Lung transplantation (LTx) is an established therapeutic option for end-stage pulmonary disease. However, it remains restricted by donor lung scarcity. Donor's lungs are rejected frequently due to severe lung damage caused by aspiration or neurogenic pulmonary oedema that can all lead to acute lung injury (ALI), and more severe acute respiratory distress syndrome (ARDS). Lung transplant patients f

For more than 30 years polyimides (PA) have been one of the main polymers for the fabrication of thin film composite membranes. Several researchers have assessed the main fabrication variables that influence the final structure of the polyamide layers including monomer concentration, solvents, additives in aqueous and organic phases and type of support to mention few [1,2]. However, few studies ha

We urgently need to move from a fossil-based to a bio-based society. From a Swedish perspective, a promising way forward are biorefineries with an integrated production of materials, chemicals, and energy from the softwood species Scots pine (Pinus sylvestris) and Norway spruce (Picea abies). A diverse set of process routes will be necessary to produce all intermediates and commercial products. In

Analytical chemistry is a sub-discipline of chemistry that even young schoolchildren encounter at an early stage in their education. Gravimetry and measurement uncertainties are aspects that form a part of such education, as well as measurements of pH and colorimetry. These are all an integral part of children’s early educational experiences, which shows the importance of this discipline within th

BACKGROUND: Reproductive factors have been shown to be differentially associated with risk of estrogen receptor (ER)-positive and ER-negative breast cancer. However, their associations with intrinsic-like subtypes are less clear.METHODS: Analyses included up to 23 353 cases and 71 072 controls pooled from 31 population-based case-control or cohort studies in the Breast Cancer Association Consortiu

STUDY QUESTION: Does previous bariatric surgery (BS) in women affect cumulative live birth rate in IVF?SUMMARY ANSWER: Women having had BS seem to have the same cumulative live birth rate as non-operated women of the same BMI at IVF treatment.WHAT IS KNOWN ALREADY: Because of the perinatal risks of obesity to mother and infant as well as impaired outcomes of IVF, obese women are advised to reduce

Background: One of the challenges of the 21st century is the high turnover rate in the nursing profession due to burnout and mental illness. From a biopsychosocial perspective, an individual's personality is an important vulnerability-resilience factor that comprises four temperament traits (i.e., a person's emotional reactions) and three character traits (i.e., self-regulation systems). Indeed, d