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Deep learning takes the pain out of back breaking work - Automatic vertebral segmentation and attenuation measurement for osteoporosis

Background: Osteoporosis is an underdiagnosed and undertreated disease worldwide. Recent studies have highlighted the use of simple vertebral trabecular attenuation values for opportunistic osteoporosis screening. Meanwhile, machine learning has been used to accurately segment large parts of the human skeleton. Purpose: To evaluate a fully automated deep learning-based method for lumbar vertebral

Tuning Pluronic F127 phase transitions by adding physiological amounts of salts : A rheology, SAXS, and NMR investigation

Specific ion (Hofmeister) effects in colloid and biological systems represented a scientific challenge for more than 100 years. Recently, possible applications, based on their rationalization, are emerging. Here, Cl-, SO42-, SCN- anions and Na+, K+, Mg2+ cations are added at physiological concentration (∼0.15 mol/kg) to Pluronic F127 20 wt% aqueous solutions to suitably tune phase transitions for

Cytotoxic lymphocytes in COPD airways : Increased NK cells associated with disease, iNKT and NKT-like cells with current smoking

Background: Cytotoxic lymphocytes are increased in the airways of COPD patients. Whether this increase is driven primarily by the disease or by smoking is not clear, nor whether it correlates with the rate of decline in lung function. Methods: Bronchoscopy with BAL was performed in 52 subjects recruited from the longitudinal OLIN COPD study according to pre-determined criteria; 12 with COPD and a

Factors Associated with Withdrawal Time in European Colonoscopy Practice : Findings of the European Colonoscopy Quality Investigation (ECQI) Group

The European Colonoscopy Quality Investigation (ECQI) Group aims to raise awareness for improvement in colonoscopy standards across Europe. We analyzed data collected on a sample of procedures conducted across Europe to evaluate the achievement of the European Society of Gastrointestinal Endoscopy (ESGE) mean withdrawal time (WT) target. We also investigated factors associated with WT, in the hope

Metabolic dysfunction-associated steatotic liver disease has become the most common cause of hepatocellular carcinoma in Sweden : A nationwide cohort study

Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most prevalent chronic liver disease globally, and can lead to hepatocellular carcinoma (HCC), a leading cause of cancer-related death. We aimed to determine the extent to which MASLD is an increasing cause of HCC in Sweden and to determine clinical characteristics associated with underlying MASLD. Using the Swedish quality re

Complete computational design of high-efficiency Kemp elimination enzymes

Until now, computationally designed enzymes exhibited low catalytic rates1, 2, 3, 4–5 and required intensive experimental optimization to reach activity levels observed in comparable natural enzymes5, 6, 7, 8–9. These results exposed limitations in design methodology and suggested critical gaps in our understanding of the fundamentals of biocatalysis10,11. We present a fully computational workflow

What do we mean with integrated risk management? : A research profiling comparing DRM and other fields of risk management

The concept of integrated risk management (IRM) has developed as a response to more interconnected and complex contexts. To investigate how the concept is used and what is meant with integration in the scientific literature, a research profiling was carried out across all kinds of risk management applications. 1094 publications from scientific journals, conference proceedings, and books were inclu

Small-bowel capsule endoscopy in patients with Meckel's diverticulum : clinical features, diagnostic workup, and findings. A European multicenter I-CARE study

Background and Aims: Meckel's diverticulum (MD) may remain silent or be associated with adverse events such as GI bleeding. The main aim of this study was to evaluate indicative small-bowel capsule endoscopy (SBCE) findings, and the secondary aim was to describe clinical presentation in patients with MD. Methods: This retrospective European multicenter study included patients with MD undergoing SB

The velocity distribution of white dwarfs in Gaia EDR3

Using a penalized maximum likelihood, we estimate, for the first time, the velocity distribution of white dwarfs in the solar neighbourhood. Our sample consists of 129 675 white dwarfs within 500 pc in Gaia Early Data Release 3. The white dwarf velocity distributions reveal a similar structure to the rest of the solar neighbourhood stars, reflecting that white dwarfs are subject to the same dynami

Association of Ultraprocessed Food Consumption With Risk of Dementia : A Prospective Cohort

BACKGROUND: There has been a growing body of evidence associating consumption of ultra-processed foods (UPF) with adverse health outcomes including depression, cardiovascular disease, all-cause mortality. However, whether UPF are associated with dementia is unknown. The authors investigated the associations between UPF and dementia incidence in UK biobank.METHODS: We included 72,083 participants (

A Body Shape Index (ABSI) achieves better mortality risk stratification than alternative indices of abdominal obesity : results from a large European cohort

Abdominal and general adiposity are independently associated with mortality, but there is no consensus on how best to assess abdominal adiposity. We compared the ability of alternative waist indices to complement body mass index (BMI) when assessing all-cause mortality. We used data from 352,985 participants in the European Prospective Investigation into Cancer and Nutrition (EPIC) and Cox proport

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Matematikcentrum Matematik NF Report on MATM33 Differential Geometry, Autumn 2024 Course leader: Sigmundur Gudmundsson Other teaching staff: None Number of students: 23 Results at the first exam: 3 V, 8 G, 6 U Results at the re-take exam: 4 V, 5 G, 0 U Evaluation Summary of the student survey: See appendix. https://www.matematik.lu.se/matematiklu/personal/sigma/surveys/HT-2024-Differential-Geometr

https://www.maths.lu.se/fileadmin/maths/Matematik_NF/Kursutvaerderingar/HT2024/MATM33HT24.pdf - 2026-05-21

In situ passivation monitoring of Ti-6Al-4V in 3.5 wt% NaCl solution using ECAFM

This study systematically investigates the passivation and dissolution mechanisms of TC4 (Ti-6Al-4V) in 3.5 wt% NaCl solution using in situ electrochemical atomic force microscopy (ECAFM), complemented by X-ray photoelectron spectroscopy (XPS) and X-ray absorption spectroscopy (XAS). Potentiodynamic polarization initially identified the electrochemical behavior of TC4, delineating passive, dissolv

Concordance between elderly patients' understanding of and their primary healthcare physician's diagnosis of heart failure

Objective. The objective was to study primary healthcare patients' understanding of their diagnosis of heart failure (HF), using patients treated for diabetes mellitus (DM) as a comparative group. Design. A cross-sectional community based study. Setting. Karlskrona community situated on the Swedish south-east coast with 60 600 inhabitants. Subjects. A total of 1402 subjects, aged 60 - 96 years in

Rapid production of cellulase-free xylanases by solventogenic Clostridia from rumen

Xylanases without contaminating cellulases are produced by a wide variety of aerobic bacteria and fungi but anaerobic organisms producing such enzymes are rare. Clostridial species viz., Clostridium beijerinckii LU-1, C. acetobutylicum LU-1, C. butyricum and C. bifermentans LU-1 isolated from rumen produced xylanase (E.C. 3.2.1.8) of 1.5-4.2 U/ml on oat spelt xylan as sole carbon source. Cellulose

Interaction between prenatal growth and high-risk genotypes in the development of type 2 diabetes

Early environmental factors and genetic variants have been reported to be involved in the pathogenesis of type 2 diabetes. The aim of this study was to investigate whether there is an interaction between birthweight and common variants in the TCF7L2, HHEX, PPARG, KCNJ11, SLC30A8, IGF2BP2, CDKAL1, CDKN2A/2B and JAZF1 genes in the risk of developing type 2 diabetes. A total of 2,003 participants fro

Recent evolutionary diversification of a protist lineage

Here, we have identified a protist (dinoflagellate) lineage that has diversified recently in evolutionary terms. The species members of this lineage inhabit cold-water marine and lacustrine habitats, which are distributed along a broad range of salinities (0-32) and geographic distances (0-18 000 km). Moreover, the species present different degrees of morphological and sometimes physiological vari

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NUMA01 VT2-2021 2021-12-14 Sammanfattningen Kursen undervisades enbart via Zoom under pandemi villkor. Deltagare: 83 Godkända: 62 (=75%) Svar i kursutvärderingen: 3 Kursansvarig: Claus Führer 2229637, claus.fuhrer@math.lth.se För att bli godkänt krävs två godkända hemuppgifter samt en godkännt präsentation av slutprojektet. Det fanns mycket få responser till kursutvärderingen. Mitt intryck är att

https://www.maths.lu.se/fileadmin/maths/Matematik_NF/Kursutvaerderingar/VT2021/NUMA01VT21_all.pdf - 2026-05-21

MATB22-vt23

MATB22-vt23 Centre for Mathematical Sciences Faculty of Science Centre for Mathematical Sciences Division of Mathematics and Numerical Analysis Course Analysis for MATB22 and ÄMAD02 Linear Algebra 2, Spring Term 2023 Course Information Lecturer: Kjell Elfström Teaching assistants: Niklas Kotarsky, Thomas Munn, Jan Henrik Thomm Number of students: MATB22: 57 newly registered and 16 re-registered. Ä

https://www.maths.lu.se/fileadmin/maths/Matematik_NF/Kursutvaerderingar/VT2023/MATB22VT23.pdf - 2026-05-21

20240319_FA_Discussion Brief_ENG

20240319_FA_Discussion Brief_ENG Localising human rights: Challenges and opportunities in the Asia-Pacic Region Keywords: Human rights-based approach, local governance, challenges and opportunities Abu Al-Rasheed T. Tanggol1 1 This discussion brief was developed by Abu Al-Rasheed T. Tanggol, independent consultant, with comments and feedback from Windi Arini and Johanna Sjöwall of Raoul Wallenberg

https://rwi.lu.se/wp-content/uploads/2024/05/20240319_FA_Discussion-Brief_ENG.pdf - 2026-05-21