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Given the proven benefits of screening to reduce diabetic ketoacidosis (DKA) likelihood at the time of stage 3 type 1 diabetes diagnosis, and emerging availability of therapy to delay disease progression, type 1 diabetes screening programs are being increasingly emphasized. Once broadly implemented, screening initiatives will identify significant numbers of islet autoantibody-positive (IAb+) child
Given the proven benefits of screening to reduce diabetic ketoacidosis (DKA) likelihood at the time of stage 3 type 1 diabetes diagnosis, and emerging availability of therapy to delay disease progression, type 1 diabetes screening programmes are being increasingly emphasised. Once broadly implemented, screening initiatives will identify significant numbers of islet autoantibody-positive (IAb+) chi
Endometriosis is a condition that can cause significant pain and discomfort for women, and the clinical and surgical treatments available have variable efficacy and can have adverse effects. These drawbacks often lead to poor adherence and therapeutic failure. Consequently, there has been increasing interest in the use of nutritional supplements as an adjuvant therapy for endometriosis. To facilit
PURPOSE: This study describes the effects of a mobile geriatric acute team (GAT) treating acutely ill geriatric patients in their homes. GAT offered more advanced diagnostic and treatment options than are normally available to primary-care led mobile teams. The aim of this study was to evaluate if interventions by GAT had effect on the number of emergency department (ED) visits, hospitalisations,
Universities have an important role in moving society towards a more sustainable future. However, this will require us to repurpose universities, reorienting and refocusing the different university domains (education, research, campus, and outreach) towards sustainability. The governance structures and processes used to embed sustainability into the activities and operations of the institution are
Besides thriving on altered glucose metabolism, cancer cells undergo glutaminolysis to meet their energy demands. As the first enzyme in catalyzing glutaminolysis, human kidney-type glutaminase isoform (KGA) is becoming an attractive target for small molecules such as BPTES [bis-2-(5 phenylacetamido-1, 2, 4-thiadiazol-2-yl) ethyl sulfide], although the regulatory mechanism of KGA remains unknown.
Family accommodation (FA) is widely-recognised as an important clinical phenomenon in obsessive–compulsive disorder (OCD) and anxiety disorders, and is related to poorer treatment outcomes. However, FA has not been quantitatively explored in Body Dysmorphic Disorder (BDD). The aim of this study was to investigate the patterns and correlates of maternal accommodation in adolescent BDD, and its asso
Lately, interest has increased in using Virtual Reality (VR) in residential care facilities to increase accessibility to nature experiences. It is widely acknowledged that nature benefits health, and various theories exist regarding its restorative effects. Studies of virtual natural environments often start from predetermined mediating mechanisms and health outcomes. However, virtual nature is fu
Background Mothers attending prevention of mother-to-child transmission (PMTCT) of HIV clinics seem to lack knowledge on many aspects of PMTCT, among which is breastfeeding. Breastfeeding recommendations in PMTCT have changed several times over the years leaving some confused and doubtful of what is currently recommended. One method shown to help improve their knowledge and acceptance of PMTCT rec
Human reproductive success requires both producing children and making investments in the development of offspring. To a large extent these investments are made by the parents of the child, but researchers are now looking beyond the nuclear family to understand how extended kin, notably grandmothers, enhance reproductive success by making transfers to progeny of different kinds. The extent to whic
Background: Despite recent advances in neuroimaging and neurocritical care, severe traumatic brain injury (TBI) is still a major cause of severe disability and mortality, with increasing incidence worldwide. Antisecretory factor (AF), commercially available as Salovum®, has been shown to lower intracranial pressure (ICP) in experimental models of, e.g., TBI and herpes encephalitis. The aim of this
Background: The growing challenges of population aging create a pressing need for specialized geriatric medicine services to effectively address the complex health needs of older adults and influence supportive healthcare policies. Older patients may present clinical complexity with multimorbidity, disability, and/or frailty, necessitating a shift from the traditional organ-oriented clinical appro
Post-flashover fires inherently lead to external fire plumes, constituting a hazard for rapid fire spread over façades. As multi-storey mass timber buildings with internal visible timber surfaces become more common, there are concerns that such buildings would produce larger external plumes and hazards (assuming all other parameters equal). The literature reveals only indications of this, and how
Playing outdoors in nature with peers has been attributed most importance for children's healthy development but is increasingly marginalized because of the attractiveness of screen-based play. Careful merging of digital technology into outdoor play environments rich on nature elements could potentially help bridge digital play with more traditional play activities outdoors. A systematic compariso
Study design: Psychometric study. Objectives: To i) describe the translation process and ii) explore the data completeness, targeting, reliability and aspects of validity of the Swedish version of Moorong Self-Efficacy Scale (s-MSES). Settings: Community rehabilitation program. Methods: Ninety-two program participants and 42 peer mentors with spinal cord injury (SCI) in Active Rehabilitation train
Medial temporal lobe (MTL) substructures are the earliest regions affected by neurofibrillary tangle pathology-and thus are promising biomarkers for Alzheimer's disease (AD). However, automatic segmentation of the MTL using only T1-weighted (T1w) magnetic resonance imaging (MRI) is challenging due to the large anatomical variability of the MTL cortex and the confound of the dura mater, which is co
Purpose: to propose two enhancements for the European Union’s Circular Material Use rate (CMU): inclusion of Preparation for Reuse (PfR) flows and enhanced reproducibility across lower levels of analysis. Methods: PfR flows are added to the material flow Sankey Diagram. The Local Circularity Rate (LCR) is based in the CMU and is broke down in three waste-related ratios: recovered-to-treated (RCV-t
The main objective of this paper is to develop a readiness index model that can serve as an analytical tool for exploring the achievements of the electrification of transportation systems. We have applied this readiness index model to evaluate the readiness positioning of China, Norway, and Sweden towards transportation electrification. We have chosen these three countries as they represent divers
