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Challenges and opportunities for increasing the use of low‑risk plant protection products in sustainable production. A review

Plant production systems worldwide are struggling to meet the diverse and increasing needs of humankind while also facing challenges such as climate change and biodiversity loss. This, combined with the desirable transition from the use of conventional pesticides to more sustainable plant protection solutions, has led to an urgent, and increasing, need for lowrisk plant protection products (PPPs)

The effects of oral nutritional supplements on endometriosis-related pain : A narrative review of clinical studies

Endometriosis is a condition that can cause significant pain and discomfort for women, and the clinical and surgical treatments available have variable efficacy and can have adverse effects. These drawbacks often lead to poor adherence and therapeutic failure. Consequently, there has been increasing interest in the use of nutritional supplements as an adjuvant therapy for endometriosis. To facilit

Scheduling of Industrial Control Traffic for Dynamic RAN Slicing with Distributed Massive MIMO †

Industry 4.0, with its focus on flexibility and customizability, is pushing in the direction of wireless communication in future smart factories, in particular, massive multiple-input-multiple-output (MIMO) and its future evolution of large intelligent surfaces (LIS), which provide more reliable channel quality than previous technologies. At the same time, network slicing in 5G and beyond systems

Anxiety symptoms preceding suicide: A Swedish nationwide record review

BackgroundThe literature on the relationship between anxiety and suicidal behaviors is limited and findings are mixed. This study sought to determine whether physicians noted anxiety symptoms and suicidality in their patients in the weeks and months before suicide.MethodsData were derived from a nationwide medical record review of confirmed suicides in Sweden in 2015. Individuals with at least one

The Swedish version of the Moorong Self-Efficacy Scale (s-MSES) – translation process and psychometric properties in a community setting

Study design: Psychometric study. Objectives: To i) describe the translation process and ii) explore the data completeness, targeting, reliability and aspects of validity of the Swedish version of Moorong Self-Efficacy Scale (s-MSES). Settings: Community rehabilitation program. Methods: Ninety-two program participants and 42 peer mentors with spinal cord injury (SCI) in Active Rehabilitation train

Report on 4 cases with decreased recovery due to neutralizing antibodies specific for PEGylated recombinant factor VIII

Background: The immunogenicity, safety, and efficacy of recombinant factor VIII (rFVIII) have gained increasing interest after the introduction of extended half-life products with various modifications of the rFVIII molecule, such as covalent attachment of polyethylene glycol (PEG). Anti-PEG antibodies may be associated with a temporary reduction of FVIII recovery, but according to previous studie

Performance of a [18F]Flortaucipir PET Visual Read Method Across the Alzheimer Disease Continuum and in Dementia with Lewy Bodies

Background and ObjectivesRecently, the US Food and Drug Administration approved the tau-binding radiotracer [18F]flortaucipir and an accompanying visual read method to support the diagnostic process in cognitively impaired patients assessed for Alzheimer disease (AD). Studies evaluating this visual read method are limited. In this study, we evaluated the performance of the visual read method in pa

Perception and acquaintance of stroke specialists on non-inferiority trials : An international survey

Introduction: The adoption of non-inferiority trial designs for assessing new interventions in stroke treatment is on the rise. We designed a survey to assess stroke specialists' understanding and familiarity with non-inferiority trials and margins. Methods: A brief web-based questionnaire was sent to the members of the World Stroke Organization (WSO). The median acceptable non-inferiority margins

Did Grandmothers Enhance Reproductive Success in Historic Populations? : Testing Evolutionary Theories on Historical Demographic Data in Scandinavia and North America

Human reproductive success requires both producing children and making investments in the development of offspring. To a large extent these investments are made by the parents of the child, but researchers are now looking beyond the nuclear family to understand how extended kin, notably grandmothers, enhance reproductive success by making transfers to progeny of different kinds. The extent to whic

Prediction of underlying atrial fibrillation in patients with a cryptogenic stroke : results from the NOR-FIB Study

BACKGROUND: Atrial fibrillation (AF) detection and treatment are key elements to reduce recurrence risk in cryptogenic stroke (CS) with underlying arrhythmia. The purpose of the present study was to assess the predictors of AF in CS and the utility of existing AF-predicting scores in The Nordic Atrial Fibrillation and Stroke (NOR-FIB) Study.METHOD: The NOR-FIB study was an international prospectiv

Modeling China's terrestrial ecosystem gross primary productivity with BEPS model : Parameter sensitivity analysis and model calibration

Terrestrial ecosystems are the largest sink for carbon, and their ecosystem gross primary productivity (GPP) regulates variations in atmospheric carbon dioxide (CO2) concentrations. Current process-based ecosystem models used for estimating GPP are subject to large uncertainties due to poorly constrained parameter values. In this study, we implemented a global sensitivity analysis (GSA) on paramet

Production of pions, kaons, and protons as a function of the relative transverse activity classifier in pp collisions at √s = 13 TeV

The production of π ±, K±, and (p ¯) p is measured in pp collisions at s = 13 TeV in different topological regions of the events. Particle transverse momentum (p T) spectra are measured in the “toward”, “transverse”, and “away” angular regions defined with respect to the direction of the leading particle in the event. While the toward and away regions contain the fragmentation products of the near

Assessment of the Impact of Interior Insulation on Exterior Walls in Three Swedish Buildings

Among thermal improvements of external walls in heritage buildings, interior insulation of external walls might be the only option. However, interior insulation is associated with several risks of damage due to the diminishment of the hygrothermal performance of the existing wall. This project aims to assess the impact of available solutions for interior insulation through field measurements and h

Rectal washout in rectal cancer surgery

BackgroundRectal washout (RW) is performed to eliminate intraluminal cancer cells and thereby reducing the risk of local recurrence (LR). The overall aim of this thesis was to investigate the importance of RW in rectal cancer surgery.MethodPaper I: Survey of the current practice of RW among Swedish colorectal units.Paper II: The association between RW and 30-day postoperative complications after a

F8/F9 variants in the population-based PedNet Registry cohort compared with locus-specific genetic databases of the European Association for Haemophilia and Allied Disorders and the Centers for Disease Control and Prevention Hemophilia A or Hemophilia B Mutation Project.

BACKGROUND: Hemophilia A and B are caused by variants in the factor (F) VIII or FIX gene. Selective reporting may influence the distribution of variants reported in genetic databases.OBJECTIVES: To compare the spectrum of F8 and F9 variants in an international population-based pediatric cohort (PedNet Registry) with the spectrum found in the European Association for Haemophilia and Allied Disord

Co-creating injury prevention training for youth handball players targeting end-users at the individual, team and organizational levels

IntroductionInjury prevention training is effective in reducing injuries in youth team sports, but public health impact is limited because such training is not widely, properly, or sustainably implemented. Insufficient involvement of end-users has been identified as a main barrier to implementation. Based on results from previous studies within the I-PROTECT project, the aim was to develop a full

The evolution of respiratory chain complex I from smaller functional modules

Popular Abstract in English The cell is the basic unit in all organisms. The molecular machinery in cells converts the energy in sunlight or food into a form of energy that the cell can use for physiological processes in the organism. In humans, this molecular machinery is located in the mitochondria; therefore they are often called the power plants of the cell. The molecular machines are actuallyNADH:quinone oxidoreductase, or complex I, is a large membrane bound enzyme in the respiratory chain of living organisms, that has evolved from the combination of smaller functional building blocks. The enzyme has a conserved core structure, comprising 14 protein subunits: Seven subunits protrude from the membrane and contain a flavin and eight iron-sulfur clusters. The remaining seven subunits in

Pools and fluxes of carbon in three Norway spruce ecosystems along a climatic gradient in Sweden

This paper presents an integrated analysis of organic carbon (C) pools in soils and vegetation, within-ecosystem fluxes and net ecosystem exchange (NEE) in three 40-year old Norway spruce stands along a north-south climatic gradient in Sweden, measured 2001-2004. A process-orientated ecosystem model (CoupModel), previously parameterised on a regional dataset, was used for the analysis. Pools of so

Predicting the distribution of a suitable habitat for the white stork in Southern Sweden: identifying priority areas for reintroduction and habitat restoration

The loss of wetlands and semi-natural grasslands throughout much of Europe has led to a historic decline of species associated with these habitats. The reinstatement of these habitats, however, requires spatially explicit predictions of the most suitable sites for restoration, to maximize the ecological benefit per unit effort. One species that demonstrates such declines is the white stork Ciconia