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Penetrative ductile deformation and amphibolite-facies metamorphism prior to 1851 Ma in the western part of the Svecofennian orogen, Fennoscandian Shield

The Svecofennian orogen in the Fennosandian Shield consists of several Palaeoproterozoic meta-igneous provinces that generally young progressively southwards and westwards. The understanding of the tectonic evolution of these different provinces is linked to the ability to constrain the timing of ductile deformation and metamorphism within them. In the western part of the orogen, in central Sweden

Studies in Efficient Discrete Algorithms

This thesis consists of five papers within the design and analysis of efficient algorithms.In the first paper, we consider the problem of computing all-pairs shortest paths in a directed graph with real weights assigned to vertices. We develop a combinatorial randomized algorithm that runs in subcubic time for a special class of graphs.In the second paper, we present a polynomial-time dynamic progThis thesis consists of five papers within the design and analysis of efficient algorithms.In the first paper, we consider the problem of computing all-pairs shortest paths in a directed graph with real weights assigned to vertices. We develop a combinatorial randomized algorithm that runs in subcubic time for a special class of graphs.In the second paper, we present a polynomial-time dynamic prog

Combined solar and membrane drying technologies for sustainable fruit preservation in low-income countries – prototype development, modelling, and testing

This investigation consisted of developing and evaluating solar dryers together with semi-permeable membrane pouches for drying juicy fruits in low-income tropical countries. Two design iterations were carried out including prototype modelling and testing. The latest developed solar dryers were a passive and an active solar dryer. Modelling was initially carried out mathematically using an equatio

The prognostic value of FET PET at radiotherapy planning in newly diagnosed glioblastoma

Background: Glioblastoma patients show a great variability in progression free survival (PFS) and overall survival (OS). To gain additional pretherapeutic information, we explored the potential of O-(2-18F-fluoroethyl)-L-tyrosine (FET) PET as an independent prognostic biomarker. Methods: We retrospectively analyzed 146 consecutively treated, newly diagnosed glioblastoma patients. All patients were

Neighbourhood deprivation and type 2 diabetes in patients with bipolar disorder : A nationwide follow-up study

Patients with bipolar disorder have higher rates of type 2 diabetes (T2D) compared to the general population. Neighbourhood deprivation is associated with T2D and bipolar disorder. The aim of this study was to explore the potential effect of neighbourhood deprivation on incident T2D in patients with bipolar disorder. This nationwide open cohort study (1997–2018) included adults in Sweden ≥20 years

The development and evaluation of a hydrological seasonal forecast system prototype for predicting spring flood volumes in Swedish rivers

Hydropower makes up nearly half of Sweden's electrical energy production. However, the distribution of the water resources is not aligned with demand, as most of the inflows to the reservoirs occur during the spring flood period. This means that carefully planned reservoir management is required to help redistribute water resources to ensure optimal production and accurate forecasts of the spring

Social Jetlag and Its Association With Screen Time and Nighttime Texting Among Adolescents in Sweden : A Cross-Sectional Study

The discrepancy between social and biological clock due to sleep and wake up time difference across weekdays and weekends is referred as social jetlag. The overall aim of this study is to test whether there is an association between both screen time and nighttime texting and social jetlag among 13- to 15-year-old adolescents in Sweden. This study included a cross-sectional survey in which data wer

Modelling long-term cost-effectiveness of health promotion for community-dwelling older people

The effectiveness of health promotion for community-dwelling older people is well documented; however, there is a general lack of health economic evaluations. The aim of the present study was to evaluate long-term cost-effectiveness over 4 years of two health promoting interventions: senior meetings and a preventive home visit, for community-dwelling older people in relation to no intervention. We

Metalinguistic relativity : Does one's ontology determine one's view on linguistic relativity?

Linguistic relativity is a notion that has been met with both praise and scorn. We argue that there is correlation between theorists’ general conceptions of the nature of language, and their stance toward linguistic relativity. Starting with the proponents of the thesis, we distinguish between the relativists of the early days (Boas, Whorf) and modern neo-Whofians (Levinson, Slobin), showing that

Vortical structures and heat transfer augmentation of a cooling channel in a gas turbine blade with various arrangements of tip bleed holes

This study investigates the internal cooling processes affected by the tip bleed holes in gas turbine blades. Double bleed holes are fixed at the center of the blade tip near the pressure side and suction side, respectively. Five different arrangements of the holes along the center line of the tip are studied. The purely double holes are set as the Baseline. The purpose of the present study is to

Improving reach of health promotion during implementation in a Swedish municipality setting

Introduction: To reach the intended target group is crucial if the health effects potentially following health promoting interventions for seniors shall be realized. The aim of this study was to improve reach of health promotion during implementation in a Swedish municipality context.Material & Methods: A mixed-methods approach was applied during four phases in which recruitment and interventi

Outcome data from >10 000 multiple myeloma patients in the Danish and Swedish national registries

Objective: We describe real-world evidence (RWE) from the nationwide Swedish and Danish registries that provide important information on incidence and outcome in multiple myeloma (MM). Method: First line treatment data on more than 10.000 MM patients from Denmark and Sweden between 2005–2018 are presented. Key results from research conducted within the Swedish and Danish myeloma registries are sum

The management of women with ductal carcinoma in situ of the breast in Australia and New Zealand between 2007 and 2016

Background: The incidence of detected ductal carcinoma in situ (DCIS) continues to increase and now accounts for 14% of all breast cancer, and 20%–25% of screen-detected cases. Treatment trends of DCIS are important in order to inform the ongoing debate about possible overdiagnosis and overtreatment, but have not been investigated for over a decade in Australia and New Zealand. Against this backgr

Clinical preventive services for patients at risk for cardiovascular disease, National Ambulatory Medical Care Survey, 2005-2006

INTRODUCTION: Clinical preventive services can detect diseases early, when they are most treatable, but these services may not be provided as recommended. Assessing the provision of services to patients at risk for cardiovascular disease (CVD) could help identify disparities and areas for improvement.METHODS: We used data on patient visits (n = 21,261) from the National Ambulatory Medical Care Sur

Siliceous Raw Material Exploitation at Hort de la Boquera Site (Margalef de Monsant, Tarragona, España) : First Results from La-Icp-Ms Analysis

Research on the sourcing of siliceous raw materials in Prehistory has taken a step forward with the addition of geochemical techniques and elemental analysis to the archaeopetrological method. Counter to the macroscopic techniques, which retain an elevated subjective percentage in their results, geochemical techniques and especially LA-ICP-MS analysis generate objective, quantifiable and usable da

The influence of women's fear, attitudes and beliefs of childbirth on mode and experience of birth

Background: Women's fears and attitudes to childbirth may influence the maternity care they receive and the outcomes of birth. This study aimed to develop profiles of women according to their attitudes regarding birth and their levels of childbirth related fear. The association of these profiles with mode and outcomes of birth was explored.Methods: Prospective longitudinal cohort design with self

Increased frequency of retinopathy of prematurity over the last decade and significant regional differences

Purpose: Retinopathy of prematurity (ROP) causes childhood blindness globally in prematurely born infants. Although increased levels of oxygen supply lead to increased survival and reduced frequency of cerebral palsy, increased incidence of ROP is reported. Methods: With the help of a Swedish register for ROP, SWEDROP, national and regional incidences of ROP and frequencies of treatment were evalu

Analysis and exploitation of resource efficiency potentials in industrial small and medium-sized enterprises – Experiences with the EDIT Value Tool in Central Europe

Material and energy costs represent about 50% of the operating costs incurred by European small and medium-sized enterprises (SMEs). Although the potential for resource efficiency improvements is high, the necessary awareness and human resource capacities to explore this potential are limited. Existing tools for exploration of resource efficiency improvement potentials have several shortcomings: t

Novel Approaches to ECG-Based Modeling and Characterization of Atrial Fibrillation

Popular Abstract in Swedish Förmaksflimmer är den vanligaste rytmrubbningen i hjärtat som kräver behandling. Risken att drabbas ökar med åldern och 8% av alla åttioåringar lider av förmaksflimmer. Förmaksflimmer är i sig inte livshotande, men den förhöjda risken för proppbildning i förmaken kan leda till allvarliga komplikationer såsom stroke. Det finns olika behandlingsstrategier för förmaksflimmThis thesis deals with signal processing algorithms for analysis of the electrocardiogram (ECG) during atrial fibrillation (AF). Such analysis can be used for diagnosing patients, and for monitoring and predicting their response to various treatment. The thesis comprises an introduction and five papers describing methods for ECG-based modeling and characterization of AF. Paper I--IV deal with meth

Primary brain tumours and specific serum immunoglobulin E: a case-control study nested in the European Prospective Investigation into Cancer and Nutrition cohort.

To cite this article: Schlehofer B, Siegmund B, Linseisen J, Schüz J, Rohrmann S, Becker S, Michaud D, Melin B, Bas Bueno-de-Mesquita H, Peeters PHM, Vineis P, Tjonneland A, Olsen A, Overvad K, Romieu I, Boeing H, Aleksandrova K, Trichopoulou A, Bamia C, Lagiou P, Sacerdote C, Palli D, Panico S, Sieri S, Tumino R, Sanchez M-J, Rodriguez L, Dorronsoro M, Duell EJ, Chirlaque M-D, Barricarte A, Borgq