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Autoimmune responses against the apo B-100 LDL receptor-binding site protect against arterial accumulation of lipids in LDL receptor deficient mice.

Background: Oxidation of LDL is associated with generation of autoantibodies against a large number of different aldehyde-modified peptide sequences in apo B-100. Autoantibodies recognizing peptide sequences in the LDL receptor-binding region of apo B-100 could potentially affect both cholesterol metabolism and atherosclerosis. The aim of the present study was to determine physiological effects of

Quantifying the trans influence of triphenylarsine. Crystal and molecular structures of cis-[PtCl2(SMe2)(AsPh3)] and cis-[PtCl2(AsPh3)(2)]center dot CHCl3

Reaction between a mixture of cis-trans-[PtCl2(SMe2)(2)] and 1 eqiv. AsPh3 in chloroform gives Cis-[PtCl2(SMe2)(AsPh3)] crystallizing in P2(1)/n with a = 10.397(2), b = 14.876(3), c = 13.956(3) Angstrom, beta = 90.86(3)degrees and Z = 4. Selected geometrical parameters are Pt-As 2.3531(10), Pt-S 2.262(2), Pt-Cl (trans to S) 2.301(2), Pt-Cl (trans to As) 2.328(2) Angstrom and S-Pt-As 88.85(6), S-Pt

Finding a Balance Between Being Professional and Being Personal. Experiences of Seven Psychotherapists

The aim of this study was to explore factors psychotherapists believe influence their choice of theory, method, and techniques when doing therapeutic work. Semi-structured interviews were conducted with six certified psychotherapists and one psychotherapist in training. The interviews were analyzed using Interpretative Phenomenological Analysis (IPA), a qualitative methodology which explores how i

Explore the relationship between Bowen ratio and evapotranspiration in wetlands using the maximum entropy production model

Wetlands play a critical role in the global water cycle and ecological health. However, understanding and accurately parameterizing water and heat exchanges in these areas is challenging due to the heterogeneous nature of wetland surfaces. This study extends the maximum entropy production (MEP) model to simulate wetland evapotranspiration (ET) by integrating NDVI dynamics, water evaporation, and p

How successful employees at Corporate Market in Síminn develop their competence at work: an interview study of some of the employees' own experiences.

In today's ever changing business world, the competitiveness of organizations relies on employees' competencies, which entails the fact that employees' contributions become more valuable than ever before. The main purpose of the study was to identify which strategies are used by successful employees at Corporate Market in Síminn (an Icelandic company which handles telecommunications) i

Upplevelser av ätstörningsbehandling: en uppföljning av de långsiktiga effekterna av en dagvårdsbehandling.

The aim of this essay is to examine which help a group of women with eating disorders had from thier treatment in daycare in 2004. The aim is to examine how the women have experienced this treatment and how they live today. The central questions are: what was their life situation like before the treatment, what was their experience of the treatment, how could the treatment have been better and how

Singapore and ASEAN: A Study on Intra-Industry Trade

Southeast Asia, with Singapore in the lead, has seen the importance of integration, both regionally and with the rest of the world. The region has had high growth rates during the past years and it has benefited from trade creation through its free trade agreements, both multilateral and bilateral. Due to its successful FTAs, Singapore has been able to specialize in trade and has become an importa

Estimation of baseline levels of bacterial community tolerance to Cr, Ni, Pb, and Zn in unpolluted soils, a background for PICT (pollution-induced community tolerance) determination

The PICT method (pollution-induced community tolerance) can be used to assess whether changes in soil microbial response are due to heavy metal toxicity or not. Microbial community tolerance baseline levels can, however, also change due to variations in soil physicochemical properties. Thirty soil samples (0–20 cm), with geochemical baseline concentrations (GBCs) of heavy metals and from five diff

Improving reach of health promotion during implementation in a Swedish municipality setting

Introduction: To reach the intended target group is crucial if the health effects potentially following health promoting interventions for seniors shall be realized. The aim of this study was to improve reach of health promotion during implementation in a Swedish municipality context.Material & Methods: A mixed-methods approach was applied during four phases in which recruitment and interventi

Aortic stiffness and left ventricular diastolic function in children with well-functioning bicuspid aortic valves

AIMS: Aortic stiffness and diastolic function are abnormal in adults with bicuspid aortic valves (BAVs). The goal of this study was to determine the relationship between aortic stiffness and left ventricular (LV) diastolic impairment in children with well-functioning BAV and no associated congenital heart disease.METHODS AND RESULTS: This is a retrospective review of echocardiograms in children wi

Cryptorchidism in Sweden : A Nationwide Study of Prevalence, Operative Management, and Complications

Objectives: To review the cumulative prevalence, operative management, and complications of treatment for cryptorchidism in Sweden. Study design: A nationwide observational study from longitudinal register data of all Swedish-born boys 0-18 years of age, diagnosed with cryptorchidism from 2001 to 2014. Primary outcomes were occurrence and age at primary surgery. Secondary outcomes included type of

The development and evaluation of a hydrological seasonal forecast system prototype for predicting spring flood volumes in Swedish rivers

Hydropower makes up nearly half of Sweden's electrical energy production. However, the distribution of the water resources is not aligned with demand, as most of the inflows to the reservoirs occur during the spring flood period. This means that carefully planned reservoir management is required to help redistribute water resources to ensure optimal production and accurate forecasts of the spring

Considerable variation of trough β-lactam concentrations in older adults hospitalized with infection—A prospective observational study

In older adults, few studies confirm that adequate concentrations of antibiotics are achieved using current dosage regimens of intravenous β-lactam antibiotics. Our objective was to investigate trough concentrations of cefotaxime, meropenem, and piperacillin in older adults hospitalized with infection. We included 102 patients above 70 years of age. Total trough antibiotic concentrations were meas

Ultrasound imaging in reproductive medicine

One in six couples seeks help for infertility during their reproductive years. Subfertility investigations should be performed without delays (because female fertility decreases with age) and should be as noninvasive as possible. Many fertility clinics use diagnostic hysteroscopy to assess the uterine cavity and evaluate the tubal ostia. Laparoscopy is also often used to examine internal pelvic or

Site-directed primary in vitro immunization : Production of HIV-1 neutralizing human monoclonal antibodies from lymphocytes obtained from seronegative donors

The design of an in vitro immunization system based on a synthetic heterotope immunogen, which was a peptide containing both T- and B-cell epitopes, that elicited a neutralizing, primary human humoral immune response against the human immunodeficiency virus (HIV-1) is reported here. This heterotope construct contained the major neutralizing B-cell epitope, within the V3 region of glycoprotein 120

High incidence of chronic graft-versus-host disease after myeloablative allogeneic stem cell transplantation for chronic lymphocytic leukemia in Sweden : graft-versus-leukemia effect protects against relapse

Allogeneic hematopoietic stem cell transplantation (allo-SCT) is a potentially curative treatment option for eligible patients with chronic lymphocytic leukemia (CLL). However, it is known that cure of CLL is only possible if a graft-versus-leukemia effect is present. Between 1994 and 2007, 48 adults underwent allo-SCT for poor-risk CLL in Sweden. Of these, ten (21%) patients aged 24-53 years (med

Active zone protein expression changes at the key stages of cerebellar cortex neurogenesis in the rat

Signal transduction and neurotransmitter release in the vertebrate central nervous system are confined to the structurally complex presynaptic electron dense projections called "active zones." Although the nature of these projections remains a mystery, genetic and biochemical work has provided evidence for the active zone (AZ) associated proteins i.e. Piccolo/Aczonin, Bassoon, RIM1/Unc10, Munc13/U

Parsnip (Pastinaca sativa L.): Dietary fibre composition and physicochemical characterization of its homogenized suspensions

The dietary fibre composition in parsnip has been determined in the soluble and insoluble fraction, together with the physicochemical properties (morphology of particles, particle size distribution (PSD), volume fraction and rheological properties) of the parsnip suspensions at different paste concentration and degree of homogenization. The content of dietary fibre in parsnip was 30.4% of the dry

Assessment of time patterns of activity and rest in full-shift recordings of trapezius muscle activity - Effects of the data processing procedure

The purpose of this paper was to compare the effects of different data reduction procedures on the values of variables characterizing the time pattern of trapezius muscle activity during full work shifts. Surface electromyography (EMG) of the right and left upper trapezius muscles were obtained from 40 young subjects in different occupations, mainly electricians, hairdressers and students. The tar