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Cell death is an important field of biology that is linked to many other topics in medicine and biology. One of the methods to investigate cell death is through high content screening (HCS) which makes use of robotic microscopy. By this technology, cell death associated organelle membrane permeabilisation and the localisation of certain dyes can be visualised and elucidate a substantial amount of

A method for the quantitative determination of non-steroidal anti-inflammatory drugs (NSAIDs) in sewage sludge was developed and validated. The target compounds were extracted using pressurized hot water extraction (PHWE) and then purified and preconcentrated by three-phase hollow fiber liquid phase microextraction (HF-LPME) followed by LC-ESI-MS analysis. The PHWE was optimized with regard to the

This study examines the influence of vortex core precession on flame flashback of swirl-stabilised hydrogen flames. Theoretical considerations suggest that the angular velocity of a swirling flow is reduced as vortex precession causes it to acquire an eccentric motion around the central axis of the burner. The eccentric motion of the vortex generates a secondary flow, which is thought to reduce th

Public perception and anxiety of familial cancer have increased demands for clinical counseling, which may be well equipped for gene testing but less prepared for counseling of the large domain of familial cancer with unknown genetic background. The aim of the present study was to highlight the full scope of familial cancer and the variable levels of risk that need to be considered. Data on the 25

Popular Abstract in Swedish Den pågående globaliseringen skapar ett behov av ökad kommunikationskompetens bland svenskar som arbetar ute i världen. Denna studie baseras på beskrivningar av de kommunikationsprocesser som används av svenskar, när de möter icke-svenskar på yrkets vägnar vid arbete utanför Sverige. Beskrivningarna baseras på intervjuer. Studien är inriktad på tre områden. De kommunikaGlobalization creates a need for increased communication competence among Swedes working on the global arena. This study is based on reports of communication processes used by Swedes when interacting professionally with non-Swedes. The reports are derived from interviews. The study focuses on three areas. The communication strategies developed by the respondents for intercultural communication. Th

We study how the results of molecular dynamics (MD) simulations are affected by various choices during the setup, e.g., the starting velocities, the solvation, the location of protons, the conformation of His, Asn, and Gln residues, the protonation and titration of His residues, and the treatment of alternative conformations. We estimate the binding affinity of ligands to four proteins calculated

Abstract in UndeterminedAn efficient lighting control systems (LCS) should take advantage of the natural light available, but this presents some technical challenges as well as user related issues. So far, the assessment of lighting energy consumption of LCS has been based on technical features rather than the occupants’ acceptance.This article presents the results of a monitoring study providing

Although COPD is a major disease worldwide there is a perplexing current uncertainty about the nature of this disease. COPI) is characterized at onset and prevalently by the involvement of the lungs and bronchi, but as the disease evolves abnormalities develop in other organs and systems and the question arises: what is the pathogenesis of these respiratory and systemic impairments? Are the altera

Understanding species’ historical ranges can provide important information for conservation planning in the face of environmental change. Cromsigt et al. (this issue) comment on our recent European bison (Bison bonasus) range reconstruction, suggesting that bison were already 8000 years ago a refugee species (i.e. restricted to marginal habitat due to past human pressure) and that species distribu

Background and Objectives Keeping a small stock of liquid plasma readily available for transfusion is common practise in Sweden. We report data on complement activation markers in plasma components during storage in the liquid state and the kinetics of C3a-(desArg) after transfusion of autologous plasma with high content of C3a-(desArg) . Material and Methods Plasma components were prepared by aph

Background: Physical benefits are suggested for women and their babies when women adopt an upright position of their choice at birth. Available care options during labour influence women's impressions of what intrapartum care is. This indicates that choice of birth positions may be determined more by midwives than by women's preferences. Question: The aims of this study were to investigate factors

An efficient lighting control systems (LCS) should take advantage of the natural light available, but this presents some technical challenges as well as user related issues. So far, the assessment of lighting energy consumption of LCS has been based on technical features rather than the occupants’ acceptance. This article presents the results of a monitoring study providing some recommendations ba

The incidence of invasive group B streptococcus (GBS) infections in non-pregnant adults is increasing. Little is known about GBS in periprosthetic joint infections (PJIs). We aimed to analyse the clinical presentation of GBS PJI and its treatment in association with the outcome. The characteristics of 36 GBS PJIs collected from 10 centres were investigated. In 34 episodes, follow-up examination of

Background: Evidence for an association of alcohol consumption with prognosis after a diagnosis of breast cancer has been inconsistent. We have reviewed and summarized the published evidence and evaluated the association using individual patient data from multiple case cohorts. Methods: A MEDLINE search to identify studies published up to January 2013 was performed. We combined published estimates

Invasive exotic plant species are often expected to benefit exclusively from legacy effects of their litter inputs on soil processes and nutrient availability. However, there are relatively few experimental tests determining how litter of exotic plants affects their own growth conditions compared to congeneric native plant species. Here, we test how the legacy of litter from three exotic plant spe

The main purpose of the Thesis work is to conduct an assessment of both the way companies currently account for their waste costs, and of the potential relevancy of engaging in a more comprehensive cost accounting for waste in terms of achieving industrial waste minimisation and cost optimisation. In order to do so, literature about environmental and cost accounting was reviewed, an empirical stud

Karst är landskap och karakteristika som är viktiga både ur hydrologisk och geologisk synpunkt och som är utvecklade genom vattnets vittring av oftast karbonathaltiga stenar. Denna uppsats kartlägger världens karstområden, beskriver egenskaper av karst och karsthydrologi och strävar efter att definiera problem och möjligheter med vattenhantering i karstlandskap. Akvifärer i karst skiljer sig i månSummary: Water is, and will in the near future be even more, a key issue for the global development, and for issues concerning equal rigts for all mankind. Water is a necessity and a scarce resource in great parts of the world and it therefore exists a great need for development and management of the world’s waters. With fresh waters being increasingly accentuated for their importance in global de

De senaste 100 åren har den globala medeltemperaturen ökat i genomsnitt 0,74 grader, vilket medför stora effekter för såväl människor som djur och natur. En av de största konsekvenserna till den globala uppvärmningen är att den stigande havsnivån blir allt mer påtaglig världen över. Glaciärer och inlandsisar har börjat smälta allt mer, där avsmältningen medför en global ökning i havsnivån. HavsnivThe rising sea level is becoming more evident around the world as less as well as more developed countries are starting to fully comprehend the consequenses. It is also generally accepted that the sea level rise is accelerated by human-induced global warming. Glaciers and ice sheets are melting more and more, which together with temperature induced thermal expansion of the seas which leads to a gl

Uppsatsens syfte är att redogöra för nuvarande gällande rätt gällande internprissättning I kombination med immateriella rättigheter. Benämningen internprissättning refererar till priser i en transaktion som sker mellan bolag i en intressegemenskap. Kombinationen av de två ämnena är av intresse då vi kan se en ökning av koncerninterna transaktioner såväl som en ökad handel med immateriella rättigheThe purpose of this essay is to account for the current legal situation concerning transfer pricing in combination with intangible property. The term transfer pricing refers to prices in a transaction between associated enterprises. The combination of the two subjects is of current interest as there is an increase of controlled transactions as well as trade with intangible property. The method of