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This Master Thesis has been done at Business Unit Global Service at Ericsson Ltd in Stockholm. It is written by a student who is studying a Master of Science in Electrical Engineering and it is done in co-operation with the institution of Production Management at Lund Institute of Technology. The Master Thesis examine whether it is possible to make a general cost distribution, towards which each M
Sammanfattning: Arbetets syfte var att göra en utvecklingshistorisk tolkning av området kring Örseryd, mellersta Blekinge. Ett 2000 x 600 m stort område ytkarterades, varefter olika enheter definierades och korrelerades med tidigare undersökningar utförda i Blekinge. Arbetet koncentrerades sedan till torvmarksområden påträffade under ytkarteringen. Tre torvmarksområden kan urskiljas inom undersöknSummary: The aim of this investigation was to study the Holocene history of a river valley near the village of Örseryd, situated in the middle part of the county of Blekinge in South Sweden. Covering 2000 x 600 m the area was investigated by survey mapping. Grain size analysis were made on representative samples and the different sediments were correlated to lithostratigraphic units defined in ear
There are about 3 500 churches protected under the Heritage Conservation Act in Sweden today. These churches still belong to living congregations that want to be able to adapt them to the needs of today, just like people have done throughout history. But since the churches are protected, the congregations have to apply for a permit and that is not always given. This can lead to frustration, and yo
The work in this thesis was carried out to highlight important chemical pathways in skeletal mechanisms for the three smallest alcohol fuels (methanol, ethanol and npropanol), two representative fuel alkanes n-heptane and n-decane, and finally the biodiesel surrogates, methyl-decanoate, methyl-5-decenoate, and methyl-9-decenoate. This aim was set up to further the efforts of creating Computational
Background: Eczema control has been identified as an important outcome by key stakeholders in eczema research (including patients, carers, healthcare professionals and researchers) but no validated instruments for the domain have been identified. Objectives: To develop a measurement instrument to capture a patient's perspective of eczema control that is suitable for use in eczema clinical trials.
Importance: General practitioners (GPs) sometimes initiate a treatment despite not expecting it to improve patients' symptoms by any physiological mechanism. These essentially placebo treatments are ethically controversial, and their frequency is unclear. They involve risks for patients, but to estimate these, more data are needed. Objective: To develop a more precise overview of the rate at which
BACKGROUND: The cross-sectional association between cerebral tissue oxygen saturation (SctO 2) and heart failure (HF) has been previously studied, but the prognostic significance of SctO 2 in HF remains uncertain. This study aimed to assess the role of SctO 2 as a risk factor for all-cause mortality and rehospitalisation, as well as to explore the cross-sectional association between physical ac
Studies evaluating the relationship between platelet indices and cardiovascular (CV) outcomes yielded conflicting results. We assessed the incidence of adverse events according to baseline quintiles of platelet indices in the prospective cohort of the Malmö Diet and Cancer Study. A total of 30,314 individuals (age 57 ± 8 years) were followed for a median of 16 years (468,490 person-years). Outcome
The trace element selenium is of essential importance for the synthesis of a set of redox active proteins. We investigated three complementary serum selenium status biomarkers in relation to overall survival and recurrence following diagnosis of primary invasive breast cancer in a large prospective cohort study. The Sweden Cancerome Analysis Network – Breast Initiative (SCAN-B) is a prospective po
GLPG1972/S201086 is a disintegrin and metalloproteinase with thrombospondin motif-5 (ADAMTS-5) inhibitor in development as an osteoarthritis disease-modifying therapy. We report the safety, tolerability, pharmacokinetics, and pharmacodynamics (turnover of plasma/serum ARGS-aggrecan neoepitope fragments [ARGS]) of GLPG1972 in 3 randomized, double-blind, placebo-controlled phase 1 trials. Study A, a
BACKGROUND: Bivalirudin was not superior to unfractionated heparin in patients with myocardial infarction (MI) treated with percutaneous coronary intervention and no planned use of GPI (glycoprotein IIb/IIIa inhibitors) in contemporary clinical practice of radial access and potent P2Y12-inhibitors in the VALIDATE-SWEDEHEART randomized clinical trial (Bivalirudin Versus Heparin in STEMI and NSTEMI
Background: Influenza vaccination early after myocardial infarction (MI) improves prognosis but vaccine effectiveness may differ dependent on type of MI. Methods: A total of 2,571 participants were prospectively enrolled in the Influenza vaccination after myocardial infarction (IAMI) trial and randomly assigned to receive in-hospital inactivated influenza vaccine or saline placebo. The trial was c
The clinical evaluation of regional delays in myocardial motion (myocardial asynchrony) has proved problematic, yet it remains an important functional parameter to evaluate. Prior attempts to quantify regional asynergy have met with limited success, often thwarted by the low temporal resolution of imaging-system data acquisition. If a delay in onset of motion of 30-40 msec is clinically important
Patient-reported outcome measures (PROMs) are the only systematic approach through which the patient's perspective can be considered by surgeons (in determining a procedure's efficacy or appropriateness) or healthcare systems (in the context of value-based healthcare). PROMs in registries enable international comparison of patient-centered outcomes after total joint arthroplasty, but the extent to
Introduction Atrial fibrillation (AF) is a major risk factor for ischaemic stroke and transient ischaemic attack (TIA), and AF detection can be challenged by asymptomatic and paroxysmal presentation. Long-term ECG monitoring after ischaemic stroke or TIA is recommended by all major societies in cardiology and cerebrovascular medicine as a secondary prophylactic measure. However, data on stroke red
BACKGROUND: Centrally inserted central catheters (CICCs) are indispensable in modern healthcare, but unfortunately, come with complications. Catheter-related thrombosis is a well-known complication reported to occur in 5-30% of patients with CICC. There is a paucity of studies that report the incidence of catheter-related thrombosis after the introduction of real-time ultrasound insertion guidance
This report represents the main findings from the first round of village-level community assessment of the economic and social impacts monitoring of COVID-19 in Myanmar. A total of 224 individuals (four per village, selected for their knowledge of the situation of the village, and representativity of key sub-groups), were interviewed across 56 villages, in two townships in every state and region a
Background: There is a need for refined risk stratification of sudden cardiac death and prediction of ventricular arrhythmias to correctly identify patients who are expected to benefit the most from implantable cardioverter-defibrillator (ICD) therapy. Methods: We conducted a registry-based retrospective observational study on patients with either ischemic (ICMP) or nonischemic dilated cardiomyopa
Hur stor makt har egentligen den svenska kungen, och hur har utvecklingen sett ut? Vilka likheter och skillnader finns att se i Danmark? Länderna har en lång historia som monarkier, och utvecklingen har på många sätt skett parallellt. Under 1800-talet gick båda länderna från att vara kungliga envälden till att närma sig en status som fullgoda parlamentariska demokratier. Likheterna som hittas i utHow great are the powers of the Swedish king in reality, and what has the development looked like? Which similarities and differences can be seen in Denmark? The countries have a long history as monarchies, and the development has in many ways taken place in parallel. During the 19th century, both countries transitioned from royal autocracies to approaching a status as fullyfledged parliamentary d
In recent years there has been much attention paid to corporate scandals, and in the Swedish media the Skandia incidents have become a serial as, years after the incidents was revealed, sentences are passed on those involved in the scandal. The former president and vice president of the joint-stock company Skandia were both prosecuted for the economic crime gross breach of faith committed by an ag
