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Type 2 diabetes mellitus (DM2) is characterized metabolically by defects in both insulin secretion and insulin action, resulting in hyperglycemia. Histopathologically, DM2 is characterized by depositions of protein in the pancreatic islets. This 'islet amyloid' is present in > 90% of patients with DM2, as well as in monkeys and cats with DM2. The pathogenesis of DM2 is heterogeneous and multifacto

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Background There is a great need for a simple and clinically useful instrument to help physicians estimate the probability of survival to discharge with a good neurological outcome (cerebral performance category, CPC = 1) in cases of in-hospital cardiac arrest (IHCA). Our aim was to validate the “Good Outcome Following Attempted Resuscitation” (GO-FAR) score in a different country with different d

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The International Midwinter Counts, organised byWetlands International, started in January 1967, butco-ordinated counts were organised along the coastsof Scania, south Sweden, already since January 1964.This paper summarises the results of the first fortyyears. During the first years full coverage was attained,but in later years the counts covered nine larger areas,containing about 75% of all wate

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Objective: The aim was to document empirical observations about antecedents to and practices of unsuitable behaviours amongst surgical trainees and develop an interview guide that could be used for the selection process. Design: A mixed methods design was adopted combining a survey distributed to senior surgeons and heads of departments, followed by semi-structured interviews with experienced surg

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Zr/TiO 2 anatase photocatalysts with 0.5, 1, 2, 5 and 7.5 mol.% Zr were prepared using pressurized hot water crystallization and their photocatalytic activity was explored in acid orange 7 photodegradation. Parent TiO

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Raptors from the orders Accipitriformes and Falconiformes have been considered to rely principally on vision. Historically, this assumption has led scientists to discount any possible sense of smell in these birds, until work on cathartid vultures indicated that these species at least rely on olfaction to find carrion. In this review I provide evidence that raptors in general have functional olfac

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Purpose of Review: This review outlines the scope of the problem in osteoporosis care and secondary fracture prevention and describes fracture prevention strategies, with a focus on the frail elderly. Recent Findings: Despite heightened awareness among patients and clinicians alike and the availability of efficacious anti-osteoporosis medications, osteoporosis is still underdiagnosed and undertrea

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Context. Observations of the Galactic bulge suggest that the disk formed through secular evolution rather than gas dissipation and/or mergers, as previously believed. This would imply very similar chemistry in the disk and bulge. Some elements, such as the α-elements, are well studied in the bulge, but others like the neutron-capture elements are much less well explored. Stellar mass and metallici

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The establishment of sustainable bioeconomies requires the utilization of new renewable biomaterials. One such material currently seen as a waste product is oat hulls. Oat hulls exhibit a great potential for the production of dietary fibres due to their exceptionally large hemicellulose content (35%). Their recalcitrant structure however requires a suitable pre-treatment method to access and proce

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BackgroundAssessment and treatment of the acutely ill patient have improved by introducing systematic assessment and accelerated protocols for specific patient groups. Triage systems are widely used, but few studies have investigated the ability of the triage systems in predicting outcome in the unselected acute population. The aim of this study was to quantify the association between the main com

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Global dispersal and increasing frequency of the SARS-CoV-2 spike protein variant D614G are suggestive of a selective advantage but may also be due to a random founder effect. We investigate the hypothesis for positive selection of spike D614G in the United Kingdom using more than 25,000 whole genome SARS-CoV-2 sequences. Despite the availability of a large dataset, well represented by both spike

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We evaluate a natural experiment at a Swedish university, in which students were randomized to either taking all their courses online, or to have some courses online and some on campus (blended learning). Our setting creates two groups for the online courses: One group with no access to campus whatsoever, and one group treated with campus classes in parallel, but unrelated, courses. We show that c

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Although a number of different medium access control (MAC) schemes are adopted for wireless multi-hop networks, time division multiple access (TDMA) approaches based on a periodic frame of time slots are the most common when very high efficiency is needed in terms of use of radio and energy resources. Efficient resource usage is typically based on parallel compatible transmissions from multiple no

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Studies on the natural human exposures to fine particulate matter (PM2.5) and their elements composition are practically non-existent in South America. In order to understand the natural exposure of the typical Brazilian population to PM2.5 and their trace element composition, we measured PM2.5 concentrations and collected mass on filters for nine continuous hours during a typical workday of volun

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This article explores the financial dilemma from a household level perspective of paying for primary education in Tanzania. In 2001, the primary education fee was abolished in a serious attempt to achieve free universal primary education. By eliminating what was perceived as the main obstacle for reaching education for all, the enrollment rates were expected to increase. However, the schools thems

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Several countries have carried out surveys of managed honeybee colonies, the results of which suggest high loss rates all over the world. Although Latin America is an important apicultural region, estimates of honeybee colony losses are lacking. This study quantified colony losses in Argentina during the 2015-16 season. Overall, the survey included 28,204 honeybee colonies, of which 15.5% were rec

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Common beans of the Mayocoba variety were cooked (178 min) and evaluated regarding their chemical composition and starch digestibility in vitro. Mean physical characteristics of the Mayocoba grain were: thousand-kernel weight, 443.0 (±0.98)g; length, 12.45mm; width 7.84mm and thickness, 6.44mm. Total starch content in Mayocoba bean was 40.24% (dmb). The available starch was 22.87%, whereas resista

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Large-scale linguistically annotated corpora have played a crucial role in advancing the state of the art of key natural language technologies such as syntactic, semantic and discourse analyzers, and they serve as training data as well as evaluation benchmarks. Up till now, however, most of the evaluation has been done on monolithic corpora such as the Penn Treebank, the Proposition Bank. As a res

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Eight family caregivers of elderly dementia sufferers participated in in-depth interviews regarding their experiences of giving care. They were selected according to strain, isolation, disappointment and emotional involvement, measured on a 'caregiver burden' scale. Structural analyses of the interviews identified six categories reflecting the feelings and experiences of the caregivers. The first