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Based on the philosophical notion that language embodies thought we investigated whether a habitual tendency for intrusive thought that younger and older participants report over a period of 100 sessions, spread out over about 6 months, is associated with brain regions related to language production. In favour of this hypothesis, we found that individual differences in habitual intrusive thoughts
FKBPs (FK506-binding proteins) have long been recognized as key regulators of the response to immunosuppressant drugs and as co-chaperones of steroid receptor complexes. More recently, evidence has emerged suggesting that this diverse protein family may also represent cancer biomarkers owing to their roles in cancer progression and response to treatment. FKBPL (FKBP-like) is a novel FKBP with role
Fodor is infamous for his radical conceptual nativism, McDowell likewise well-known for suggesting that concepts extend “all the way out” into the world and arguing against what he calls (per Sellars) The Myth of the Given: the idea that non-conceptual percepts justify conceptual frameworks. One need not go so far as either researcher, however, in allowing merit to their arguments. It seems we are
We present a dielectric continuum model that, at a semiquantitative level, explains why ion pair formation in water is favored by like-sized ions over unlike-sized pairs. Using both classical and ab initio continuum approaches, we show that the now well-established empirical rule, the so-called “law of matching water affinities”, can be rationalized in terms of ion solvation. Namely, pairing of di
The Centre party weathered what amounted to an almost existential mid-term public opinion crisis, to end up outperforming its coalition partners in the 2014 general election. Although it too fell back, it shed a notable proportion of tactical support voters, and actually increased its share of genuine, first-preference, voters. The Centre party has revisited and refreshed its ideological foundatio
Adsorption of uncharged homopolymers of various flexibilities in good solvent onto planar surfaces Lit various polymer-surface interaction strengths have been investigated by employing a coarse-grained bead-spring polymer model using simulation techniques. The polymer flexibility ranged from fully flexible to rod-like polymers, and the adsorption strength varied from weak to strong adsorption. Equ
Diffuse large B-cell lymphoma (DLBCL) shows a higher incidence in males versus females. Epidemiological studies have shown that female gender is a favorable prognostic factor, which may be explained by estrogens. Here we show that when grafting human DLBCL cells to immunocompromised mice, tumor growth in males is faster. When treating mice grafted with either germinal center or activated B-cell li
n this work the prebiotic effect of different cyclodextrins, CDs, on the viability of model probiotic bacteria (Lactobacillus rhamnosus GG) encapsulated in carboxymethyl cellulose-chitosan (CMC-Cht) hybrid particles was studied. All the CDs tested were observed to considerably improve the viability (quantitatively like common prebiotics, such as corn starch) and encapsulation efficiency when compa
Orexins are neuropeptides selectively expressed in a small number of neurons in the lateral–posterior hypothalamus. We measured orexin-A in the cerebrospinal fluid (CSF) of 66 patients with major depressive disorder (MDD), dysthymia and adjustment disorder after a suicide attempt. Blood samples confirmed that the patients were free from antidepressive and neuroleptic medication at the time of the
LIDAR-data från mätstationen Polly, som är en del av Arrhenius-laboratoriet och belägen på Stockholms universitets tak, används för att bestämning av planetära gränsskiktshöjden. För detta ändamål användes en stabil ”wavelet covariance transform” metod för analys av LIDAR-datasignalerna från åren 2011-2012. Endast molnfria dagar med högtrycks- förhållande är med i undersökningen för att minska mänLIDAR data from the Polly system on the roof of the Arrhenius laboratory at Stockholm University are used to determine the planetary boundary layers (PBL) height distribution. To this end, a wavelet covariance transform method is employed to analyze LIDAR measured data signals from the years 2011-2012. Only data with high pressure cloud free condition are used to reduce “bad” data. The main result
Dendritic cells are the sentinels of the immune system, linking the innate and adaptive immune response. Myeloid and dendritic cell models have been successfully used in in vitro approaches to predict adverse outcomes such as skin sensitization. We here exposed a well-characterized human dendritic cell-like cell line to agricultural chemicals, including fungicide formulations, active ingredients,
Three patients, men aged 47 and 30 and a woman aged 48 years, presented with appendicitis-like symptoms, progressive abdominal distension, and an ovarian pelvic mass, respectively. All three were diagnosed with pseudomyxoma peritonei. Treatment consisted of cytoreductive surgery followed by hyperthermic intraperitoneal chemotherapy (HIPEC). After a mean follow-up of 64 months (range: 19-89) after
Nanoporous metals fabricated by dealloying have a unique bi-continuous, sponge-like porous structure with ultra-high surface area. The unique properties of these materials, especially nanoporous gold, have numerous potential applications in sensors and actuators and in energy-related applications such as catalytic materials, super-capacitors, and battery supports. The degree of porosity and size o
The binding of protein to solid surfaces often induces changes in the structure, and to investigate these matters we have selected two different protein−nanoparticle systems. The first system concerns the enzyme human carbonic anhydrase II which binds essentially irreversibly to the nanoparticles, and the second system concerns human carbonic anhydrase I which alternate between the adsorbed and fr
Zinc is essential for all organisms and yet detrimental at elevated levels. Hence, homeostasis of this metal is tightly regulated. The Zrt/Irt-like proteins (ZIPs) represent the only zinc importers in metazoans. Mutations in human ZIPs cause serious disorders, but the mechanism by which ZIPs transfer zinc remains elusive. Hitherto, structural information is only available for a model member, BbZIP
In light of the Danish society becoming more and more secular, we wish to examine in this study, how a group of young Christians in a free church in Copenhagen, Denmark are experiencing stigmatization based on their religious belief, as well as how they choose to handle it. Furthermore, this study shows how young Christians develop their identity based on said stigmatization and the meeting with t
Genom EU-medlemskapet har Sveriges arbetsmarknad utvidgats till EES-medlemsländers yttre gränser i och med den fria rörligheten. Detta, tillsammans med en ökad gränsöverskridande rörelse, EU-utvidgningen i öst, samt EU-domstolens praxis i form av Lavaldomen, har satt press på den svenska modellen och mer närmare det svenska kollektivavtalssystemet. Uppsatsen uppmärksammar och påvisar att den svensThrough the membership in EU and the free movement, Sweden’s labour market has been extended to the EES-countries outer national boarders. This, together with an increased transboundary movement, EU-extension in the east, and the EU-Court´s judgements such as Laval, has put pressure on the Swedish model and more in detail the Swedish collective agreement system. This essay highlights and indicates
Alveoli are sac-like structures in the distal lung specialised for gaseous exchange. Alveolar epithelium facilitates efficient respiration through a thin and robust arrangement of type-I (AT1) and type-II (AT2) pneumocytes, supported by tight junctions and surfactant-rich alveolar lining fluid. Chronic diseases like pulmonary fibrosis, asthma, and sarcoidosis compromise alveolar integrity, resulti
