Filtyp
OBJECTIVE: Genome-wide association studies have begun to elucidate the genetic architecture of type 2 diabetes. We examined whether single nucleotide polymorphisms (SNPs) identified through targeted complementary approaches affect diabetes incidence in the at-risk population of the Diabetes Prevention Program (DPP) and whether they influence a response to preventive interventions. RESEARCH DESIGN
The complement system is an essential effector of both innate and acquired immune responses. Due to its destructive potential, tight regulation is required. The contribution of complement has been associated with the pathogeneses in a wide range of diseases. In this thesis, aspects of complement activation were investigated in disorders characterized by thrombocytopenia.In papers I and II, clinica
A key factor for the insulin response to oral glucose is the pro-glucagon derived incretin hormone glucagon-like peptide-1 (GLP-1), together with the companion incretin hormone, glucose-dependent insulinotropic polypeptide (GIP). Studies in GIP and GLP-1 receptor knockout (KO) mice have been undertaken in several studies to examine this role of the incretin hormones. In the present study, we revie
Kortkorta nanopinnar bäst för hjärnan – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Kortkorta nanopinnar bäst för hjärnan 2015-01-16 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Om elektroder i framtiden ska föras in i mänskliga hjär
https://www.vetenskaphalsa.se/kortkorta-nanopinnar-bast-for-hjarnan/ - 2026-07-21
A cDNA clone (Mt4) was isolated as a result of a differential screen to identify genes showing altered expression during the interaction between Medicago truncatula and the vesicular-arbuscular mycorrhizal (VAM) fungus Glomus versiforme. Mt4 represents a M. truncatula, mRNA that contains numerous short open reading frames, the two longest of which are predicted to encode polypeptides of 51 amino a
Objectives: The present study aimed to examine hypoperfusion in response to epinephrine following the administration of a local anaesthetic. The . concentration of epinephrine that causes maximal hypoperfusion, the . spread of hypoperfusion in the tissue and the . time to the stabilization of hypoperfusion were investigated. Methods: Blood perfusion was monitored using laser Doppler velocimetry an
Sömn är nödvändigt för att din kropp och hjärna ska kunna återhämta sig och bearbeta alla intryck. Sömnen påverkar också din förmåga att minnas och lära dig nya saker. Samtidigt är bristande sömn den kanske enskilt största bidragande orsaken till psykisk ohälsa. Ta del av våra tips för att få rätsida på dina sömnvanor. Genvägar till sidans innehåll:Faktorer som påverkar sömnenHar du svårt att sova
https://www.lu.se/student/studentstod-och-halsa/studenthalsan/somn-och-somnsvarigheter - 2026-07-24
Institutionen för kulturvetenskaper, Idé- och lärdomshistoria LITTERATURLISTA Kurslitteratur för HISS34, Historiska studier: Tematisk litteraturfördjupning (7,5 hp). Historisk orientering efter historismens kris, VT 2026 Litteraturen söks i FINN om inget annat anges. Obligatorisk litteratur Croce, Benedetto, ”History and Chronicle” [History – Its Theory and Practice], i: Theories of History, red.
https://www.ht.lu.se/media/utbildning/dokument/kurser/HISS34/20261/Historisk_orientering_efter_historismens_kris.pdf - 2026-06-29
Institutionen för kulturvetenskaper, Idé- och lärdomshistoria LITTERATURLISTA Kurslitteratur för HISS34, Historiska studier: Tematisk litteraturfördjupning (7,5 hp). Historisk orientering efter historismens kris, VT 2026 Litteraturen söks i FINN om inget annat anges. Obligatorisk litteratur Croce, Benedetto, ”History and Chronicle” [History – Its Theory and Practice], i: Theories of History, red.
Even though the relative contribution of neutralizing antibodies (Nab) to prevent progression to AIDS during HIV-1 infection is still unclear, the induction of broadly NAb directed against HIV-1 through vaccination is considered to represent an important goal for the development of HIV-1 vaccines. Factors contributing to the induction of NAb may include the strength and duration of antigenic stimu
Background We designed the EURAMOS-1 trial to investigate whether intensified postoperative chemotherapy for patients whose tumour showed a poor response to preoperative chemotherapy (≥10% viable tumour) improved event-free survival in patients with high-grade osteosarcoma. Methods EURAMOS-1 was an open-label, international, phase 3 randomised, controlled trial. Consenting patients with newly diag
The aim of this study was to examine whether autoantibodies to: ZnT8-Tryptophan (ZnT8WA), ZnT8-Arginine (ZnT8RA) or ZnT8-Glutamine (ZnT8QA) correlated with C-peptide or other autoantibodies and to assess diagnostic sensitivity of ZnT8WRQA. Specimens from 270 newly diagnosed diabetic subjects (age 15--34 years) and after five 5 years duration of disease were examined. Four linear regression models
Objectives: To address the efficacy and safety of secukinumab in comparison with placebo in active rheumatoid arthritis (RA) patients who had an inadequate response to tumor necrosis factor (TNF) inhibitors. Methods: Databases of PubMed, Embase, and Web of Science were searched to identify the relevant randomized controlled trials (RCTs). R
This paper presents a combinatorial auction which is of particular interest when short completion times are of importance. It is based on a method for approximating the bidders' preferences over two types of items when complementarity between the two may exist. The resulting approximated preference relation is shown to be complete and transitive at any given price vector. It is shown that an appro
Moocar är öppna nätkurser som du kan läsa när det passar dig. De är kostnadsfria, digitala och tillgängliga för alla – oavsett tidigare erfarenhet. Här hittar du aktuella moocar som ges vid Lunds universitet. En mooc är en nätbaserad universitetskurs som du kan gå utan att vara antagen till en utbildning. Moocar ger inga högskolepoäng och kan inte ingå i en universitetsexamen, men du kan få ett ce
https://www.lu.se/moocar - 2026-07-22
Purpose: To address the systematic bias in whole-brain dual flip angle (DFA) T1-mapping at 7T by optimizing the flip angle pair and carefully selecting RF pulse shape and duration. Theory and Methods: Spoiled gradient echoes can be used to estimate whole-brain maps of T1. This can be accomplished by using only two acquisitions with different flip angles, i.e., a DFA-based approach. Although DFA-ba
The Consiglio Lab investigates how biological sex impacts human immunity using systems immunology approaches. Generally, females mount more robust immune responses than males, resulting in lower severity of infections, decreased frequency of cancer, but increased prevalence of autoimmunity. Yet, we do not fully understand the precise mechanisms that underlie such sex discrepancies. Our lab combiThe Consiglio Lab investigates how biological sex impacts human immunity using systems immunology approaches. Generally, females mount more robust immune responses than males, resulting in lower severity of infections, decreased frequency of cancer, but increased prevalence of autoimmunity. Yet, we do not fully understand the precise mechanisms that underlie such sex discrepancies. Our lab combi
