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Hani Saghir -Institutionen för kliniska vetenskaper, Lund

21 maj 2025 14:00 | Halvtidskontroll Title: Gene Expression Biomarkers in the Neoadjuvant Setting of Breast CancerMain supervisor: Niklas Loman (MD, PhD,Associate Professor)Reviewers: Gottfrid Sjödahl (PhD, Associate Professor); Julia Ellbrant (MD, PhD)AbstractBackground:Biomarkers are critical in personalized cancer care for tumor classification and treatment selection. Breast cancer, a molecular

https://www.intramed.lu.se/evenemang/hani-saghir-institutionen-kliniska-vetenskaper-lund - 2026-07-01

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Decomposition of soil organic matter (SOM) contributes significantly to the global carbon (C) cycle and climate feedbacks. SOM decomposition depends on soil microbial activities, and these activities are driven by the availability of C and other nutrients. Plant root exudates are known to alter decomposition of SOM, a phenomenon referred to as rhizosphere priming effects (RPE). In order to predictDecomposition of soil organic matter (SOM) contributes significantly to the global carbon (C) cycle and climate feedbacks. SOM decomposition depends on soil microbial activities, and these activities are driven by the availability of C and other nutrients. Plant root exudates are known to alter decomposition of SOM, a phenomenon referred to as rhizosphere priming effects (RPE). In order to predict

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Introduction: In kidney transplantation (KT), the role of the intravascular innate immune system (IIIS) in response to ischemia-reperfusion injury (IRI) is not well-understood. Here, we studied parallel changes in the generation of key activation products of the proteolytic cascade systems of the IIIS following living donor (LD) and deceased donor (DD) transplantation and evaluated potential assoc

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The current study aimed to characterize changes in EEG-related measures after noxious stimuli in neonates, and to assess their potential utility as measures of pain and/or discomfort during neonatal intensive care.Seventy-two healthy term infants were investigated: Twenty-eight had a non skin-breaking pin-prick on the heel, randomized to receive either oral glucose (n=16) or water (n=12) before th

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In this thesis, I attempted to achieve a better understanding of the nature of X-linked polymorphic loci using a female-limited X chromosome (FLX) experimental evolution in Drosophila melanogaster. I expected that expressing the evolved X chromosome will result in an increase in female fitness and a decrease in male fitness. I first investigated the effect of an experimentally evolved female-limit

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Some colors might have different connotations depending on people’s cultural backgrounds. When talking about evacuation, the color employed for exit signs and flashing lights plays a significant role because it is in charge of transmitting a message to the evacuees, either danger or safety. The aims of this study are to evaluate the influence of red and green emergency wayfinding systems on people

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Ubiquitination is a post-translational modification process that has a very important role in the homeostasis of eukaryotic cells. Linkage-specific ubiquitination determines the final destination of modified protein. Ubiquitination has also been reported to regulate inflammasome function and IL-1β degradation. Secretion of IL-1β by macrophages in response to inflammasome activation is a key proces