Filtyp
Experiments were performed to characterize the so-called leak current of the slowly adapting stretch receptor neurone of the European lobster with respect to its ionic basis, its kinetics and its pharmacology. Estimates of the leak current were obtained by subtraction of a Na-K pump current and of an unspecific impalement current from a non-dynamic ('instantaneous') current, recorded in a voltage
Sense of Coherence (SOC) measures an individual's positive, or salutogenic, orientation toward her/his capacities, environment, future, and life. SOC comprises three factors: comprehensibility (the sense of one's own life as ordered and understandable); manageability (the perception of available resources and skills to manage stressors); and meaningfulness (the overall sense that life is filled wi
Background: Hyperlipidaemia is a major risk factor for cardiovascular disease, and atherosclerosis is the underlying cause of both myocardial infarction and stroke. We have previously shown that the Pro251 variant of perilipin-2 reduces plasma triglycerides and may therefore be beneficial to reduce atherosclerosis development. Objective: We sought to delineate putative beneficial effects of the Pr
Objectives: Clinical trials have demonstrated the efficacy of vedolizumab in inflammatory bowel disease (IBD). However, these findings may not reflect the clinical practice. Therefore, we aimed to describe a vedolizumab-treated patient population and assess long-term effectiveness. Materials and methods: Patients initiating vedolizumab between 1 June 2014 and 30 May 2015 were identified through th
Anesthetized, paralyzed and mechanically ventilated pigs were exposed to extreme hypercapnia (PaCO2 approximately 20 kPa) at FiO2 0.4 for 480 min, with (n = 6) or without (n = 6) continuous infusion of isotonic buffers (bicarbonate and trometamol). Arterial pH was higher in buffered animals than controls, 7.21 +/- 0.01 vs 7.01 +/- 0.01 (mean +/- s.e.mean, P < 0.01). Serum osmolality and PaCO2 did
We have recently described frequency-dependent effects of mobile phone microwaves (MWs) of global system for mobile communication (GSM) on human lymphocytes from persons reporting hypersensitivity to electromagnetic fields and healthy persons. Contrary to GSM, universal global telecommunications system (UMTS) mobile phones emit wide-band MW signals. Hypothetically, UMTS MWs may result in higher bi
Objective: The insulin responsive adiponutrin (PNPLA3 or ADPN) gene shows association with obesity and in vitro adipocyte lipolysis. This study aimed to replicate the association between PNPLA3 variants and obesity, and to investigate their effect on insulin resistance and beta-cell function. Methods: rs738409 (Met148Ile) and rs2072907 (C to G) were genotyped using TaqMan allelic discrimination as
Quantitative in-cylinder measurements of soot volume fraction in a single-cylinder HSDI Diesel engine, based on a VOLVO D5, has been carried out using the laser-induced incandescence (LII) technique using laser excitation at 1064 nm and an ICCD camera with prompt gate detection. Quantitative data was obtained by relating the LII signal response from the engine to that from a calibration flame. The
Transport in and through biological membranes that consist of lipid bilayers has a crucial role in many applications in the food or pharmaceutical industries. How to deliver an enzyme through the membranes without damaging the enzymatic activity or the "shelf-life" of the enzyme has been of large interest since 1970 [29-30]. In this work, we have shown that a thin lipid sponge phase (L3)
Background. In SBRT of lung tumours no established relationship between dose-volume parameters and the incidence of lung toxicity is found. The aim of this study is to compare the LQ model and the universal survival curve (USC) to calculate biologically equivalent doses in SBRT to see if this will improve knowledge on this relationship. Material and methods. Toxicity data on radiation pneumonitis
Stroke causes life long disabilities where few therapeutic options are available. Using electrical and magnetic stimulation of the brain and physical rehabilitation, recovery of brain function can be enhanced even late after stroke. Animal models support this notion, and housing rodents in an enriched environment (EE) several days after experimental stroke stimulates lost brain function by multise
This degree project aimed to produce a standardized food product enriched with 14g polar lipids (PL) and compare its effects on glycemic response and appetite sensations both acutely and following a second meal in healthy individuals. In order to elucidate the viability of enriching a prebaked product with polar lipids researchers spent multiple weeks assessing variations in recipe, cook time, coo
Today cities are the result of centuries of history and human development, accelerated during the past 100 years. Post-industrialization, modernism’s top-down city planning approach, and the prioritisation of motor vehicle design over humans resulted in more people moving to cities, more space needed to allocate new vehicles, expansion over rural areas, and exponential pollution growth. Thus, huma
Objectives: To determine clinical characteristics, outcome and occurrence of comorbidities in patients with biopsy-confirmed giant cell arteritis (GCA) treated with intravenous methylprednisolone (IVMP) vs those receiving oral glucocorticoids (OGC) only. Methods: A retrospective study included patients with GCA diagnosed from 2004 through 2019. Clinical and laboratory characteristics, and cumulati
AIMS/HYPOTHESIS: The incidence of type 1 diabetes increased during the pandemic in various countries. SARS-CoV-2 infections may trigger the development of type 1 diabetes, but the evidence is inconclusive. This study aimed to assess trends in type 1 diabetes incidence between 2007 and 2023, and to quantify the association between SARS-CoV-2 infections and the risk for developing type 1 diabetes.ME
BACKGROUND: Long COVID and cardiovascular autonomic dysfunction, including postural orthostatic tachycardia syndrome (POTS), present significant healthcare challenges. Long-term monitoring is challenging due to the evolving nature of symptoms and the limited availability of objective diagnostic tools. With over 200 million electrocardiogram (ECG)-enabled smartwatches sold worldwide, these devices
Microsoft Word - Brochure RS public outreach_2020_edited.docx 1 Wallenberg Centre for Molecular Medicine Research School Interfaces between Systems 2019/2020 2 Cover art by Inés Nascimento Caiado Copyright by all authors Faculty of Medicine Printed in Sweden by Media-Tryck, Lund University Lund 2020 3 4 Thank you to our funding sources and all those who have worked to make this research school pos
https://www.wcmm.lu.se/sites/wcmm.lu.se/files/brochure_rs_public_outreach_2020_edited.pdf - 2026-07-23
Sweden’s post-war development positioned it among Europe’s most motorised countries, contributing to high car ownership and widespread reliance on private vehicles. While cars remain essential to modern life, their overuse challenges national climate goals and public health. Efforts to reduce car use have increasingly focused on promoting sustainable al ternatives such as walking, cycling, and pub
Denna uppsats undersöker räckvidden av det straffrättsliga ansvaret för försök till sexualbrott mot barn på nätet när polisen uppträder som barn, samt hur detta ansvar förhåller sig till rätten till en rättvis rättegång enligt artikel 6 i EKMR. Rättsläget har förändrats påtagligt under de senaste åren. Genom NJA 2023 s. 393 ”Vapenattrappen” preciserade Högsta domstolen det straffbara området för This thesis examines the scope of criminal liability for attempted sexual offences against children online when a police officer impersonates a child, and how this liability relates to the right to a fair trial under Article 6 of the ECHR. The legal position has shifted markedly in recent years. In NJA 2023 p. 393 "Vapenattrappen" (The weapon replica), the Supreme Court of Sweden clarif
Problem analysis Remote sensing of drought: Sentinel data for monitoring and quantitative assessment of impacts Mitro Müller Department of Physical Geography and Ecosystem Science, Lund University Supervisors: Jonas Ardö, Lars Eklundh, Sadegh Jamali, Per-Ola Olsson Summary: A drought is an extended period when the balance between rainfall, evapotranspiration, surface flow, and subsurface flow diff
https://www.nateko.lu.se/sv/sites/nateko.lu.se.sv/files/2021-11/Mitro_Muller_Problem_Analysis.pdf - 2026-07-23
