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Ischemic stroke triggers neurogenesis from neural stem/progenitor cells (NSPCs) in the subventricular zone (SVZ) and migration of newly formed neuroblasts towards the damaged striatum where they differentiate to mature neurons. Whether it is the injury per se or the associated inflammation that gives rise to this endogenous neurogenic response is unknown. Here we showed that inflammation without c
Background: Limited information exists on the framework and content of postgraduate education in internal medicine in Europe. This report describes the results of a survey of postgraduate training in internal medicine in the European countries. Methods: Two online questionnaire-based surveys were carried out by the European Board of Internal Medicine, one on the practice of internists and the othe
Background: Current information on the role of internists in the European countries is scarce. This report describes the results of a survey of the practice of internists in Europe. Methods: Two online questionnaire-based surveys were carried out by the European Board of Internal Medicine, one on the practice of internists and the other on postgraduate training in internal medicine. The national i
Object. Cerebral vasospasm following subarachnoid hemorrhage (SAH) leads to reduced cerebral blood flow (CBF) and to cerebral ischemia, in some cases even producing infarction and long-term disability. The goal of the present study was to investigate the hypothesis that inhibition of neurokinin-1 receptors (NK1Rs) by administration of L-822429 blunts the decrease in CBF as well as cerebrovascular
BACKGROUND: A synthetic oxytocin analogue, barusiban, was shown to potently inhibit oxytocin-induced activity of myometrium from term pregnant women. The responsiveness to vasopressin was not influenced by the compound. OBJECTIVE: To test the effect of barusiban and a reference compound, atosiban, on oxytocin-induced activity of myometrium from women at preterm pregnancy in comparison to myometriu
A dosimetry system based on radioluminescence (RL) and optically stimulated luminescence (OSL) from carbon doped aluminium oxide (Al2O3:C) crystals was developed for in vivo absorbed dose measurements in mammography. A small cylindrical crystal of Al2O3:C (diameter 0.48 mm and length 2 mm) was coupled to the end of a 1 mm diameter optical fibre cable. Owing to their small size and characteristic s
Background: Exhaled breath temperature (EBT) has been suggested as a marker of airway inflammation in asthma. Objectives: The aim of the present study was to investigate EBT in asthmatic subjects compared to healthy controls after an exercise challenge test, and in subjects with exercise-induced bronchoconstriction compared to subjects without, and to compare with body temperatures. Methods: A tot
Septic tanks with subsequent soil treatment systems (STS) are a common treatment technique for domestic wastewater in rural areas. Phosphorus (P) leakage from such systems may pose a risk to water quality (especially if they are located relatively close to surface waters). In this study, six STS in Sweden (11-28 years old) were examined. Samples taken from the unsaturated subsoil beneath the distr
Phthalates are ubiquitous indoor pollutants which have been associated with child airway disease although results are inconclusive. This study examined associations between phthalate levels in residential indoor dust and croup during infancy. Settled indoor dust was collected in 482 homes of 6-month-old infants in the Swedish Environmental Longitudinal, Mother and child, Asthma and allergy (SELMA)
Purpose: Hodgkin lymphoma (HL) survivors are known to have increased cardiac mortality and morbidity. The risk of developing cardiovascular disease after involved node radiotherapy (INRT) is currently unresolved, inasmuch as present clinical data are derived from patients treated with the outdated mantle field (MF) technique. Methods and Materials: We included all adolescents and young adults with
Background: The 2020 European Society of Cardiology (ESC) guidelines for the diagnosis and management of patients with non-ST elevation-acute coronary syndrome (NSTE-ACS) recommend early invasive coronary angiography in high-risk patients and no routine pre-treatment with oral P2Y12 receptor inhibitor in NSTE-ACS patients prior to defining coronary anatomy. Objective: To assess the implementation
The PICT method (pollution-induced community tolerance) can be used to assess whether changes in soil microbial response are due to heavy metal toxicity or not. Microbial community tolerance baseline levels can, however, also change due to variations in soil physicochemical properties. Thirty soil samples (0–20 cm), with geochemical baseline concentrations (GBCs) of heavy metals and from five diff
Objective The aim of the present study was to investigate if the relation between sex and clinical outcomes in early rheumatoid arthritis varies by autoantibody status.Methods Two inception cohorts of consecutive patients with early RA (symptom duration ≤12 months) in the Southern Region of Sweden were investigated. Patients were stratified by anti-citrullinated peptide antibody (ACPA) status. The
Sexuella övergrepp utgör en mycket allvarlig integritetskränkning. För att motarbeta dessa övergrepp krävs ett starkt och välutvecklat straffrättsligt skydd. Som en följd härav har våldtäktslagstiftningen, allt sedan brottsbalkens (BrB) ikraftträdande år 1965, utvecklats till att bli alltmer offercentrerad, inkluderande och avancerad. Det är uppenbart att det rör sig om sena reformer, men icke desSexual abuses constitute a very serious integrity violation. To counter these abuses requires a strong and well-developed criminal law. As a consequence, ever since the Penal Code (PC) entered into force in 1965, the rape legislation has developed to become ever more victim-centered, inclusive and advanced. It is obvious it’s about late reforms, but nonetheless clearly that the judicial system has
With rapidly developing digitalization and the growing popularity of online learning platforms, understanding the psychological drivers behind user loyalty has become increasingly critical. This thesis investigates how Flow Experience, defined as a deep state of intense enjoyment, focus, and concentration, shapes user satisfaction and user attitudinal loyalty in the context of online learning
Denna studie undersökte möjligheten att använda icke-kontextuella mått på motivation: Tidsinvestering och Personlighet. Dessa icke-kontextuella mått utvärderades utifrån deras förmåga att predicera genomsnittligt betyg (GPA), ett vanligt använt mått på akademisk prestation och indikator för akademisk motivation. Resultaten analyserades via explorativ faktoranalys och multipel linjär regression basThis study investigated the possibility of using non-contextual measurements of motivation: Time-investment and Personality. These non-contextual measurements were evaluated based on their ability to predict Grade Point Average (GPA), a commonly used metric of academic performance and used tangible for academic motivation. Results were analysed through exploratory factor analyses (EFA) and multipl
Interneurons have been found to be important for normal cognitive function. Impairments to their growth or signaling have been indicated to be involved in the development of schizophrenia, autism and epilepsy. Defective functioning in GABA:ergic interneurons has been linked to undesired desynchronous firing in neural signals as a consequence of these interneurons firing too infrequently or not at
Syfte: Studien ämnar undersöka hur skånska mikro- och småföretag finansierar sin verksamhet och om de agerar i enlighet med pecking-order teorin. Detta görs med syftet att fylla kunskapsgapet och öka förståelsen kring finansieringsstrategier och finansieringsalternativ hos mikro- och småföretag. Det är en förhoppning att studien skall bidra med ny kunskap samt inspirera till framtida studier inom Purpose: The study aims to examine how micro and small enterprises choose to finance their activities and if they act in accordance with the pecking-order theory. This is done with the purpose to fill the knowledge gap and increase the understanding of financing strategies and financing options of micro and small enterprises. Hopefully the study will contribute to new knowledge within the research
Eventuella beteendemässiga konsekvenser av pornografianvändande har undersökts flitigt under de senaste decennierna. Forskningen har dock inte inkorporerat kontextuella aspekter av pornografianvändande eller intresserat sig för möjliga samband med användarnas egen sexualitet. Denna studies första syfte var att undersöka pornografianvändande i en icke-klinisk population av 16- till 30-åringar i SveAn increasing body of research has accumulated over last decades investigating the possible behavioral outcomes and correlates of pornography use. However, research has not incorporated contextual aspects of pornography use or it’s relation with users’ own sexuality. The first aim of this study was to investigate several aspects of pornography use in a non clinical population of 16-30 year olds’ i
The purpose of this paper is to measure living standards for the population of Chocó, Colombia, using four waves of the DHSurveys between 1990 and 2005. Recent maternal history allowed the construction of a pooled dataset of 3.055 children and 779 mothers. The concept of living standards is measured as the ability to ensure child and marriage survival subject to short term economic stress, which i
