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The "hypnotic state" and eye movements. Less there than meets the eye?

Responsiveness to hypnotic procedures has been related to unusual eye behaviors for centuries. Kallio and collaborators claimed recently that they had found a reliable index for "the hypnotic state" through eye-tracking methods. Whether or not hypnotic responding involves a special state of consciousness has been part of a contentious debate in the field, so the potential validity of their claim w

Nature by numbers: an evaluation of how DEFRA’s Biodiversity Metric 3.0 can or cannot capture rewilding outcomes

The United Kingdom’s response to the pressing biodiversity decline in England includes the Biodiversity Net Gain (BNG) policy and is operationalised through DEFRA’s Biodiversity Metric, which quantifies biodiversity into ‘biodiversity units’. This thesis evaluates how effectively the metric reflects real biodiversity outcomes at the rewilded Knepp Estate in West Sussex. Using 2005 as a baseline an

Nasal CD4+ tissue-resident memory T cells provide cross-protective immunity to influenza

CD4 tissue-resident memory T cells (TRM) are crucial adaptive immune components involved in preventing influenza A virus (IAV) infection. Despite their importance, their physiological role in the upper respiratory tract, the first site of contact with IAV, remains unclear. Here, we find that, after IAV infection, antigen-specific CD4 TRM persist in the nasal tissue (NT) compartment after infection

The sensory and neuronal mechanisms underlying long-distance migration in insects

Many animals, such as birds and bats, are capable of migrating over vast distances to specific destinations. Remarkably, even insects such as the North American Monarch butterfly and the Australian Bogong moth undertake similarly long-distance migrations to specific sites. Here, we provide an overview of our current understanding of the migration of these insects and outline the sensory cues and n

Comparison of in situ devices for the assessment of pavement subgrade stiffness

The subgrade is the top surface of a roadbed upon which the pavement structure is constructed. The purpose is to provide a platform for construction of the pavement and to support the pavement without unwanted deflection that would reduce its performance. For those reasons subgrade bearing capacity have to be investigate during the construction process as a quality control, based on the design res

Site of action of antinociceptive acupuncture like nerve stimulation in the spinal rat as visualized by the 14C-2-deoxyglucose method

Aim: It has been claimed that supraspinal structures are necessary forthe depression of nocifensive behaviour elicited by acupuncture or acupuncturelike (AL) stimulation. However, nocifensive reflexes in the spinal catwere inhibited for long periods by a mechanism releasing opieids on AL conditioning stimulation of groups II-III muscle afferents (Sj~lund and Eriksson, Neurosci.Lett. S3:264:1979).

Influences of Temperature and Secondary Environmental Parameters on Planktonic Foraminiferal Mg/Ca : A New Core-Top Calibration

The accuracy of the Mg/Ca paleothermometer is contested over the influences of secondary environmental parameters such as salinity and pH. Recent calibrations based on compiled sediment trap and laboratory culture data suggest moderate influences from salinity and pH. Core tops are the best analogues to downcore samples used for paleoceanographic reconstruction with well-constrained environmental

Genotyping of hepatitis C virus isolates by a modified polymerase chain reaction assay using type specific primers: epidemiological applications

A polymerase chain reaction (PCR)-based assay using primers against the hepatitis C core gene has been described [Okamoto et al. (1992a): Journal of General Virology 73:673-679]. Within the two major HCV genotypes 1 and 2, the Okamoto system identifies two subtypes each (1a, 1b and 2a, 2b, respectively). Typing is achieved by a primary PCR with consensus primers followed by a nested PCR with type

Kinetic and mechanistic study on the reactions of ruthenium(II) chlorophenyl terpyridine complexes with nucleobases, oligonucleotides and DNA

In this study, we investigated the ability of Ru(ii) polypyridyl complexes to act as DNA binders. The substitution reactions of three Ru(ii) chlorophenyl terpyridine complexes, i.e. [Ru(Cl-Ph-tpy)(en)Cl]Cl (1), [Ru(Cl-Ph-tpy)(dach)Cl]Cl (2) and [Ru(Cl-Ph-tpy)(bpy)Cl]Cl (3) (Cl-Ph-tpy = 4′-(4-chlorophenyl)-2,2′:6′,2′′-terpyridine, en = 1,2-diaminoethane, dach = 1,2-diaminocyclohexane, bpy = 2,2′-bi

Ambulatory oxygen for treatment of exertional hypoxaemia in pulmonary fibrosis (PFOX trial) : A randomised controlled trial

Introduction Interstitial lung diseases are characterised by scarring of lung tissue that leads to reduced transfer of oxygen into the blood, decreased exercise capacity and premature death. Ambulatory oxygen therapy may be used to treat exertional oxyhaemoglobin desaturation, but there is little evidence to support its efficacy and there is wide variation in clinical practice. This study aims to

Impacts of urban living labs on sustainability transitions : mechanisms and strategies for systemic change through experimentation

Urban Living Labs (ULL) are considered spaces to facilitate experimentation about sustainability solutions. ULL represent sites that allow different urban actors to design, test and learn from socio-technical innovations. However, despite their recent proliferation in the European policy sphere, the underlying processes through which ULL might be able to generate and diffuse new socio-technical co

Comparing through-plane diffusibility correlations in PEFC gas diffusion layers using the lattice Boltzmann method

One of the key elements in a polymer electrolyte fuel cell (PEFC) is the gas diffusion layer (GDL). The GDL offers mechanical support to the cell and provides the medium for diffusing the reactant gases from the flow plates to the electrolyte enabling the electrochemical reactions, and therefore the energy conversion. At the same time, it has the task of transporting the electrons from the active

Site-Specific Introduction of Negative Charges on the Protein Surface for Improving Global Functions of Recombinant Fetal Hemoglobin

Due to its compatible oxygen-transporting abilities, hemoglobin (Hb) is a protein of interest in the development of artificial oxygen therapeutics. Despite continuous formulation attempts, extracellular Hb solution often exhibits undesirable reactions when applied in vivo. Therefore, protein engineering is frequently used to examine alternative ways of controlling the unwanted reactions linked to

Mechanism of Ganglioside Receptor Recognition by Botulinum Neurotoxin Serotype E

The botulinum neurotoxins are potent molecules that are not only responsible for the lethal paralytic disease botulism, but have also been harnessed for therapeutic uses in the treatment of an increasing number of chronic neurological and neuromuscular disorders, in addition to cosmetic applications. The toxins act at the cholinergic nerve terminals thanks to an efficient and specific mechanism of

Cost dynamics in the deployment of photovoltaics : Insights from the German market for building-sited systems

In most studies on technology change, the analysis of cost reductions of new energy technologies has been narrow and has often neglected essential processes related to the deployment of new technologies, such as photovoltaics (PV). However, in the case of distributed PV systems, other costs than for the PV modules – aka the deployment or balance-of-system costs – are significant. This review study

The Ability of Environmental Treaties to Address Environmental Problems in Post- Conflict

This chapter examines how international environmental law pertains during and in the transition phase from armed conflict to peace. I argue that environmental treaties have the ability to fill an institutional and a legal gap, particularly in a post-conflict context, which is often characterized of institutional collapse and break down of rule of law. Environmental treaties could therefore be of r

Open Badges : Acknowledging Soft Skills Acquisition

In 2010 the Mozilla Foundation established the Digital Open Badges concept as a virtual incarnation of physical counterparts such as a paper certificate or a youth organisation merit badge. Digital Open Badges offer embedded, verifiable, metadata containing information such as the issuer and award criteria. Open Badges can be used to reward learning, participation or achievement. They can be store

Pelaren, balken, muren och tektoniken

I projektet undersöker jag hur ett enfamiljshus kan få ytterligare kvalitéer genom att göra dess konstruktion och uppbyggnad synlig. Jag låter konstruktionen vara närvarande i rummet och med hjälp av den skapa rumsliga kvalitéer. Konstruktionens materialitet och tektonik görs närvarande i rummen och ger ett mervärde. Inledningsvis tittade jag på danska villor från 60-talet som innehöll dessa kvaliIn this project, I investigate how a single-family house can get additional qualities by making its constructive and structural components visible. I let the construction be present in the room and from it create spatial qualities. The goal is to do this in a way where the materiality and tectonics of the construction are present in the rooms and give the building additional qualities. Initially I

Less Closure for Better Closure: What HR-managers should do to mitigate the negative aspects of an employee's high Need for Closure in a VUCA world

The VUCA world we face today, proposes challenges for individuals with a high Need for Closure (NFC) as they may experience decreased well-being when faced with uncertainty and ambiguity. This in turn creates a problem for organizations as their employees with a high NFC may struggle to come up with innovative solutions to the complexity they are facing, making it difficult for the organization to