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Vårt arbete syftar till att öka kunskapen om hur yttre miljöfaktorer påverkar hudsjukdom, speciellt eksem och med fokus på kontaktallergi. Kontaktallergi förekommer hos nästan 30% av den vuxna befolkningen. Det allergiska kontakteksemet kan ses var som helst på kroppen, ofta på händerna. Kliniskt kan man inte skilja eksem orsakat av inre faktorer, endogent eksem, och eksem orsakat av yttre faktoreThe work is focused on increasing our knowledge of the effect the environment has on the skin, and particularly with regard to contact allergy and allergic contact dermatitis. About 30% of the adult population has contact allergy. The allergic contact dermatitis can affect any part of the body but most often it affects the hands. Clinically it is impossible to differentiate a dermatitis caused by

We demonstrate a new scheme for extreme ultraviolet (xuv) Fourier-transform spectroscopy based on the generation of two phase-locked high-harmonic beams. It allows us to measure for the first time interferograms at wavelengths as short as 90 nm, and open the perspective of performing high-resolution Fourier-transform absorption spectroscopy in the xuv. Our measurements also demonstrate that a prec

Popular Abstract in Swedish Fysik försöker förklara naturfenomen med matematiska beskrivningar som beror på systemet som studeras. Även om vi till exempel vet hur man beskriver rörelsen av ett fallande äpple, blir övervägandet av detaljer som ett fallande äpple knappast relevant när man försöker beräkna jordens rörelse runt solen. Å andra sidan spelar partikelfysik ingen roll i beskrivandet av äppThis thesis considers numerical simulations of high energy particle collisions, and improvements in the description of multiple collimated jets of hadrons in collision events in particular. In the event simulation software called event generators, the structure of multi-jet events is determined through an interplay of the input calculation, parton showers and phenomenological hadronisation models.

BACKGROUND: Effector functions of IgG antibodies (Abs) are regulated by their Fc N-glycosylation pattern. IgG Fc glycans that lack galactose and terminal sialic acid residues correlate with the severity of inflammatory (auto)immune disorders and have also been linked to the protection against viral infection and discussed in the context of vaccine-induced protection. In contrast, sialylated IgG Ab

Vårt övergripande forskningsmål är att hitta nya sätt att behandla patienter med metastaserande bröstcancer. Även om stora framsteg i hur vi behandlar bröstcancerpatienter har gjorts under de senaste decennierna så får många patienter fortfarande återfall och metastaserande bröstcancer är fortfarande en obotlig sjukdom. Genom att identifiera signalvägar som är aktiva i metastaser och studera rikta

CSS Conference 2022: Nordisk humor i Världen Färgkodning (color coding): 10:00-12:00 Lokal H135a H135b H140 Massimo Ciaravolo Andreas Tranvik Joanna Cymbrykiewicz Anna Hultman Anna Wegener Frederique Toudoire Els Joksie Biesemans Jonas Lindkvist Aldona Zanko Lorenzo Lozzi Gallo Johan Almer 15:00-15:30 19:00-19:30 Lokal H104 (Hörsalen) H135b H140 Clemens Räthel Sabina Ivenäs Carmen Vioreanu Johan A

https://www.css.lu.se/fileadmin/user_upload/project/css/CSS_Conference/2022/CSS_2022_-_PROGRAM_20220822.pdf - 2026-07-19

The MAX4 ring is intended to be the future user facility at MAXlab. The high-brilliance 3 GeV storage ring, equipped with small gap, short period superconducting undulators, demonstrates a high mean brilliance over a wide photon energy spectrum. The ring itself is defined from the routine operation of the small gap insertion devices, which is reflected in the small aperture of the ring magnets. Th

HEIMDAL will be a multi length scale neutron scattering instrument for the study of structures covering almost nine orders of magnitude from 0.01 nm to 50 mm. The instrument is accepted for construction at the European Spallation Source (ESS) and features a variable resolution thermal neutron powder diffractometer (TNPD), combined with small angle neutron scattering (SANS) and neutron imaging (NI)

Background: The development of factor (F) VIII neutralizing alloantibodies (inhibitors) is a major complication of treatment with FVIII concentrates in hemophilia A and the etiology is still poorly understood. The low-affinity Fc gamma receptors (Fc gamma R), which are expressed on immune cells, provide an important link between cellular and humoral immunity by interacting with IgG subtypes. Genet

As global warming is proceeding due to rising greenhouse gas concentrations, the Earth system moves towards climate states that challenge adaptation. Past Earth system states are offering possible modelling systems for the global warming of the coming decades. These include the climate of the mid-Pliocene (∼ 3 Ma), the last interglacial (∼ 129-116 ka) and the mid-Holocene (∼ 6 ka). The simulations

A complete reliability study of the high-frequency characteristics for nMOSFETs on InGaAs channel with Al2O3/HfO2 gate dielectric is presented. DC gate voltage stress causes an increase in the transconductance frequency dispersion. Stress induced border traps degrade the maximum DC-transconductance, but do not react at high frequencies. The main degradation characteristics of the high-frequency me

Here we unravel the structural features of human IgM and IgA that govern their interaction with the human Fc alpha/mu receptor (hFc alpha/mu R). Ligand polymerization status was crucial for the interaction, because hFc alpha/mu R binding did not occur with monomeric Ab of either class. hFc alpha/mu R bound IgM with an affinity in the nanomolar range, whereas the affinity for dimeric IgA (dIgA) was

In solid mechanics, linear structures often exhibit (local) nonlinear behavior when close to failure. For instance, the elastic deformation of a structure becomes plastic after being deformed beyond recovery. To properly assess such problems in a real-life application, we need fast and multi-query evaluations of coupled linear and nonlinear structural systems, whose approximations are not straight

Vertical graphene (VG) is a remarkable electrode material for supercapacitors due to its large specific area, open channel structures, and numerous exposed edges with high electrochemical activity. However, flexible supercapacitors with high rate performance based on VG have yet to be investigated. Here, we report flexible supercapacitors based on VG, carbon fabric (CF) current collector, and H2SO

Herpes simplex virus (HSV) induces a receptor on infected cells that is able to bind the Fc part of immunoglobulin G (IgG). We have examined some basic physicochemical and binding properties of the Fc receptor induced on HSV-1 infected green monkey kidney (GMK) cells in its interaction with rabbit IgG. Fixation of HSV-1 infected cells with glutaraldehyde, formaldehyde, acetone or ethanol did not i

The interaction between living groups A, C and G streptococci and IgG Fc was studied using human IgG, IgG Fc and IgG Fc-intermediate (Fci) fragments, chemically modified human IgG and fragment D of staphylococcal protein A (SPA). Diethylpyrocarbonate modification of His or N-acetylimidazole modification of Tyr of human IgG resulted in the loss of its capacity to inhibit the binding of radiolabelle

Lancefield extracts of 19 types of group A streptococci as well as one group C and one group G strain were examined for agglutination of human red cells coated with various anti-Rh antibodies. Fourteen extracts agglutinated one or more of the coated cell samples, while five did not. The agglutination was inhibited by Fc but not by Fab fragments of human IgG. After mouse passages, three of the non-