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Background: Matrix metalloproteinase (MMP)-mediated degradation of the extracellular matrix is a key point in tumor development and expansion. MMP-10 is one of the most important and well-characterized members of the MMP family. In the present study, we examined MMP-10 mRNA and protein levels in non-small cell lung cancer (NSCLC). Patients and Methods: Three endogenous reference genes including GA

Miniaturization of analytical separation methods offers several advantages, including short run times, high resolution, and high recovery of the sample constituents. To optimize these parameters, the reversible adsorption (to minimize loss in resolution), as well as the irreversible adsorption (to minimize loss of analytes) must be quantified. However, no useful equation is available for the calcu

this study we investigated the effects of gastrectomy (Gx) and of the gastric hormone, ghrelin, on the expression of proteins in brown adipose tissue (BAT) that are thought to be involved in thermogenesis. Heat production in BAT is known to depend upon activation and increased expression of β3-adrenergic receptors (β3-AR) and the consequent up-regulation of uncoupling protein 1 (UCP1). Mice were s

In this article, we present a fragment model potential approach for the description of the crystalline environment as an extension of the use of embedding ab initio model potentials (AIMPs). The biggest limitation of the embedding AIMP method is the spherical nature of its model potentials. This poses problems as soon as the method is applied to crystals containing strongly covalently bonded struc

Should boxing be banned? Do the ever-so-obvious risks outweigh everyone's freedom to choose whether to expose oneself to these risks by taking up the sport? On an official level, the RCN in the UK has taken its stand--it does not! So has also the British Medical Association (BMA)--it does! With few exceptions, the responding nurses from Europe, America, and Australia in this month's column seem to

Syftet med detta examensarbete är att undersöka vad som får svenska pensionärer att migrera till Costa del Sol och hur det påverkar deras uppfattning om deras existentiella hälsa som uttryckt i mening-i-livet, sammanhang och tillit. Uppsatsen bygger på ett två veckor långt fältarbete, med observationer, samtal och ett kort frågeformulär. Den övergripande forskningsfrågan är hur migrationen har påvThe purpose of this thesis is to investigate what makes Swedish retirees migrate to Costa del Sol and how it affects their perception of their Existential Health as expressed in Meaning-in-life, Coherence and Trust, building on a two-week fieldwork, with observations, free conversations, and a short questionnaire. The overall research question is how the migration has influenced retiree’s percepti

En brandteknisk riskvärdering gällande personsäkerhet har genomförts för en av Malmö Universitets huvudbyggnader, Orkanen. Arbetet började med att arbetsgruppen fick ta del av brandskyddsdokumentation och ett platsbesök genomfördes för att bland annat inventera det befintliga brandskyddet. Med insikt om byggnaden, stödd av statistiska data om brandincidenter i liknande byggnader, har en grovriskanThe building Orkanen is a part of Malmö University properties. It houses multiple lecture halls in varied sizes, study areas, restaurant, classrooms, chemical laboratories, parking garage and the universities largest library. The following report is an evaluation of human safety in case of fire in the building. After qualitative assessment, multiple scenarios were identified. With a help of a ris

Within the field of border studies, a common theoretical assumption is that national borders and national sentiments are interconnected. Some even argue that national boundaries are a precondition of national sentiments (Anderson & O'Dowd, 1999; Paasi, 1998 (b)). If one instead looks toward cross-border regions, an equally accepted theory is that national borders create regional asymmetrie

Within the restaurant industry it is common practice to plan staffing and purchases of perishable goods based on intuition. Inaccurate predictions of demand and sales lead to poor working environments and food waste, both being significant challenges for the industry. While digitalization and innovation has enabled accurate data driven sales forecasting methods, many players in the restaurant indu

Den informationsteknologiska utvecklingen är något utav både en frälsning och en förbannelse. Å ena sidan ser vi ett stort antal människor för vilka denna utveckling i många avseenden har underlättat deras vardag, å andra sidan ser vi hur upphovsmän och rättighetsinnehavare desperat söker att se efter sina skyddade verk och komma åt intrångsgörare. Genom informationsteknologins näst intill obegränThe development of information technology has had a two-fold effect and therefore it may be considered both a blessing and a curse. On the one hand, we see a large number of people for whom this development has facilitated them to do more in terms of their everyday life, on the other, we see authors and rightholders desperately seeking to look after their protected works and target infringers. The

The response to climate change in cities has proliferated over the last few decades, and progressive climate action at the local level is now ubiquitous. More specifically, local climate action often comes in the shape of ‘climate change experiments’, radical innovations at the local level designed to respond to the imperatives of mitigating and adapting to climate change in the city. This thesis

Agriculture is an essential economic activity which sustains the livelihood of millions of people around the world. Maize is one of the most grown, consumed and traded cereals in the world mostly because of its adaptability to varied environmental conditions. Maize farming depends on climatic factors like temperature, rainfall and radiation to thrive but this also means that it is very susceptible

Dust storms are meteorological phenomena that occur in arid and semi-arid regions, causing harm to the environment and human health. The frequency and intensity of dust storms have increased in recent years due to climate change and human activities. In response, various dust storm mitigation strategies were introduced, including land use management, afforestation, and mulching. The existing resea

Terahertz radiation is a useful tool for inducing lower-energy excitations in matter, where it can be used to cause structural changes through direct interaction with the crystal lattice. Sub-picosecond optical pulses can be used to generate intense broadband terahertz pulses through optical rectification in nonlinear crystals, reaching peak electric fields of several MV/m and conversion efficienc

Litigation Public Relations (LPR) är en form av strategisk kommunikation som syftar till att vinna allmänhetens åsikt då en rättsprocess aktualiseras. Tanken är att företag genom vinst av allmänhetens dom ska kunna tjäna, mo-raliskt och ekonomisk, på rättsprocessen och eventuell medial uppmärksamhet den väcker. Uppsatsen har som syfte att kartlägga det förfarande som faller in under LPR och hur deLitigation Public Relations (LPR) is a form of strategic communication aimed at winning in the court of public opinion during any legal process. The idea is that by winning in the court of public opinion, a company may be able to gain both morally and financially from the process and its potential media cover-age. The purpose of this essay is to map out the practice that is LPR and how this practi

The State of Palestine is drafting a new constitution to replace a patchwork of foreign and outdated legislation, and to harmonise national law with dozens of ratified international treaties. Since its 2012 ascension from non-member observer ‘entity’ to non-member observer ‘state’ in the UN, Palestine has signed fifty-five multilateral treaties covering a wide range of areas. All treaties have bee

The product H2 is a new heat exchanger produced, manufactured and sold by Heatex. It has an excellent surface efficiency, in large parts because of its slim features. The slim features does however have a drawback. It isn’t as mechanically stable and robust as its earlier cousins. The product tends to deform plastically in lifting conditions, especially the heavier versions needs extra support or,

Tackling the challenge of adaptation to climate change in developing countries will require the mobilization of new and additional funding. Like other adaptation approaches, Ecosystem-based Adaptation (EbA) is threatened by a growing adaptation funding gap. Further private sector involvement, for instance in the context of innovative direct financing models for EbA, is one way to help bridge the g

This master thesis relates to future trends within the field of Business Intelligence. The purpose is to create and share knowledge about Business Intelligence. A theoretical study is necessary for both readers as mandator. With no or limited understanding of Business Intelligence it will most likely be hard to follow the discussions and results of the study. The main purpose is to increase the un