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Standardavtalet AB 04 används i stor utsträckning i offentligt upphand-lande byggentreprenadkontrakt, trots att flera av dess villkor präglas av betydande tolkningssvårigheter. Detta ger upphov till problem när villkor i entreprenadavtal kan förstås på två motstående sätt. Problemet förstärks av att offentligt upphandlade avtal som huvudregel inte får ändras efter att de har ingåtts. Avsteg från dThe standard contract AB 04 is widely used in publicly procured public works contracts, despite the fact that several of its clauses are characterised by interpretative difficulties. These issues become apparent where the clauses can be understood reasonably in two opposing ways. The problem is amplified by the general rule that publicly procured contracts may not be modified once concluded. Devia

Chronic pruritus (CP) is frequent in general medicine and the most common complaint in general dermatology. The prevalence of CP is expected to rise in the future due to the ageing population. The clinical presentation, underlying aetiology and treatment strategy of CP are heterogeneous. Also, individual treatment aims and physical, psychic and economic burdens of patients might vary. Chronic prur

Popular Abstract in Swedish Pankreascancer, cancer i bukspottkörteln, är den fjärde vanligaste orsaken till död i cancer och årligen insjuknar cirka 1000 patienter i Sverige. Överlevnaden är kort med en 5-årsöverlevnad på endast 6 procent. Pankreascancer orsakar, förutom lidande, också betydande kostnader för såväl den medicinska vården, som förluster för samhället, exempelvis i form av förtida döBackground: Pancreatic cancer is the fourth leading cause of cancer-related death. Only about 6% of patients are alive 5 years after diagnosis. One reason for this low survival rate is that most patients are diagnosed at a late stage, when the tumor has spread to surrounding tissues or distant organs. Less than 20% of cases are diagnosed at an early stage that allows them to undergo potentially cu

Melanoma remains the most aggressive form of skin cancer, characterized by high metastatic potential, genetic heterogeneity, and resistance to conventional therapies. The Melanoma MEGA-Study is a multi-center initiative designed to address these clinical challenges by integrating advanced proteogenomic profiling, clinical metadata, with AI-driven digital pathology and machine learning analytics, a

Purpose Patients' understanding of their illness is key for making informed treatment decisions, yet studies suggest an association between prognostic awareness and worse quality of life (QOL) and mood among patients with advanced cancer. We sought to explore the relationships among prognostic awareness, coping, QOL, and mood in patients with newly diagnosed, incurable cancer. Methods We assessed

Prostate cancer is a common malignancy in men and the worldwide burden of this disease is rising. Lifestyle modifications such as smoking cessation, exercise, and weight control offer opportunities to reduce the risk of developing prostate cancer. Early detection of prostate cancer by prostate-specific antigen (PSA) screening is controversial, but changes in the PSA threshold, frequency of screeni

Genetic variation can modulate gene expression, and thereby phenotypic variation and susceptibility to complex diseases such as type 2 diabetes (T2D). Here we harnessed the potential of DNA and RNA sequencing in human pancreatic islets from 89 deceased donors to identify genes of potential importance in the pathogenesis of T2D. We present a catalog of genetic variants regulating gene expression (e

The primary objective of this multicenter, multinational, epidemiological study is the identification of infectious agents, dietary factors, or other environmental exposures that are associated with increased risk of autoimmunity and type 1 diabetes mellitus (T1DM). Factors affecting specific phenotypic manifestations such as early age of onset or rate of progression or with protection from the de

Mäns våld mot kvinnor har på senaste tiden uppmärksammats, men har sedan lång tid tillbaka varit ett stort problem. Tidigare sågs det som en privat angelägenhet inom familjen medan det idag förstås som ett offentligt problem som berör flera i samhället samt flera samhällsområden. Avvikelseförklaringar till våldet har tidigare präglat förståelsen kring mäns våld mot kvinnor och frågan om våld har sMen's violence against women has recently attracted a lot of attention but has been a major problem for a long time. Previously, it was seen as a private matter within the family, while today it is understood as a public problem that affects many and several areas of society. Explanations of deviations in individuals to violence have previously characterized the understanding of men's viol

Purpose: The aim was to explore what socio-economic benefits could be made out of regional networks in an economic, environmental and social perspective. The project also aimed to investigate where there is potential for regional networks and utilization of waste heat, and what barriers exist. In order to investigate the gains that can be achieved two different models was created and then compared

Problem Definition: For several hundreds of years, mining in Bolivia has been an important part of the economy. The mining activity has a negative effect on both the environment and the health of the people. Previous studies conducted in the Lake Poopó area show elevated concentrations of heavy metals and ions harmful to people and nature. Also, previous studies indicate that the contamination fro

Alltsedan incitamentsprogrammen introducerades i Sverige med inspiration från USA i mitten på 1900-talet har beskattningen av dem orsakat såväl tillämpningsproblem som debatt. Det handlar om de situationer där ett företag erbjuder anställda aktier i bolaget antingen i form av värdepapper eller personaloptioner. Den förra medför en rättighet direkt, medan den senare innebär en framtida rätt under fSince incentive plans first arrived to Sweden with inspiration from the U.S. in the middle of the 20th century the taxation of the programs have caused application problems as well as debate. The issue concerns situations where an employee is offered shares in the company based on securities or stock options. The employee hopes that he or she will get a piece of the profit in the future, while the

Many changes have occurred in the area of immunity for high state officials during the last century. States and their High Representatives, such as Head of State, Head of Government and Foreign Ministers were at the beginning of the last century granted absolute immunities for all acts they conducted. Evolution has, however, produced new rules based more on their need to function properly and less

Immune cells of the tumor microenvironment are central but erratic targets for immunotherapy. The aim of this study was to characterize novel patterns of immune cell infiltration in non-small cell lung cancer (NSCLC) in relation to its molecular and clinicopathologic characteristics. Lymphocytes (CD3+, CD4+, CD8+, CD20+, FOXP3+, CD45RO+), macrophages (CD163+), plasma cells (CD138+), NK cells (NKp4

Infant acute lymphoblastic leukemia (ALL) with KMT2A-gene rearrangements (KMT2A-r) have few mutations and a poor prognosis. To uncover mutations that are below the detection of standard next-generation sequencing (NGS), a combination of targeted duplex sequencing and NGS was applied on 20 infants and 7 children with KMT2A-r ALL, 5 longitudinal and 6 paired relapse samples. Of identified nonsynonym

Immunotechnology Labs | LTH, Faculty of Engineering Skip to main content We use cookies and other tracking technologies to improve the user experience on our website, to show you personalised content and targeted ads, and to analyse our website traffic. Cookie Policy . Essential cookies These cookies are necessary for the website to function and cannot be turned off in our systems. These cookies d

https://www.lth.se/opendoor/labs/immunotechnology-labs/ - 2026-07-20

Lund Nano Lab | LTH, Faculty of Engineering Skip to main content We use cookies and other tracking technologies to improve the user experience on our website, to show you personalised content and targeted ads, and to analyse our website traffic. Cookie Policy . Essential cookies These cookies are necessary for the website to function and cannot be turned off in our systems. These cookies do not st

https://www.lth.se/opendoor/labs/lund-nano-lab/ - 2026-07-20

Satsning på ingenjörer och batteriforskning i budgetpropositionen Hoppa till huvudinnehåll Vi använder cookies och andra spårningsteknologier för att förbättra användarupplevelsen på vår webbplats, för att visa dig personligt innehåll och riktade annonser och för att analysera vår webbplatstrafik. Läs mer om cookies. Absolut nödvändiga cookies Dessa cookies är nödvändiga för att webbplatsen ska fu

https://www.lth.se/article/satsning-paa-ingenjoerer-och-batteriforskning-i-budgetpropositionen/ - 2026-07-20

Refugee Crisis in Europe: Open Panel Discussion Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of Programme Work Methods Focus Areas Business and Human Rights I

https://rwi.lu.se/2015/09/16/refugees-in-europe-a-crisis-of-numbers-solidarity-or-borders/ - 2026-07-21