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Can Your Genes and Lifestyle Together Shape Your Risk of Parkinson’s Disease? Parkinson’s disease (PD) is one of the most common neurodegenerative disorders worldwide, yet its causes remain only partly understood. While some people inherit rare genetic mutations that directly cause PD, for most individuals, the risk is likely influenced by a complex mix of many common genetic variants and environ

BACKGROUND. Early and accurate detection of infectious respiratory diseases like COVID-19 and tuberculosis (TB) plays a crucial role in effective management and the reduction of preventable mortality. However, molecular diagnostic tests for these infections are expensive and not easily implementable in resource-limited settings, which suffer the majority of the burden. Lung Ultrasound (LUS) presen

Oat is a cereal that contains high lipid content when compared to other cereals and is a potential oil crop. Oats also have high content of lipase enzymes when compared to other cereals, that causes hydrolytic rancidity which causes the soapy bitter taste that may develop in oats. Therefore, oats that are intended for human consumption are heat treated to inactivate lipase enzymes and thus, to imp

Development of a novel gene therapy against cancer Despite tremendous efforts and achieved advances, cancer is still the leading cause of death worldwide, which underlines the need to develop novel curative approaches. In the past decade, we witnessed the rapid development of immunotherapy – novel treatment strategies based on harnessing the patient´s very own immune system to fight cancer. Altho

Transcriptional Burst Kinetics of Dosage Compensation in Chicken Sex chromosome combinations are different between sexes in many animal species. In therian mammals, females hold XX and males hold XY, which is called male heterogametic system. In birds, the sex chromosome system is female heterogametic (ZZ in males and ZW in females). The gene dosage imbalance between sexes (Xm:XXf or Zf:ZZm) and

Physical Properties of Prebiotic Membranes One of the most fundamental questions in science that remains unanswered today is the question of the origin of life on Earth. Life is defined as a chemical system with the capacity of self-replication and undergoing Darwinian evolution. Origin of life research focuses on the transition of physics and chemistry to such a chemical system. For life to ari

The shift to an activity-based way of working entails a change in how we view our work and our workplace. Some years ago, not many people had heard of activity-based working, but today there are many organizations around the world that apply an activity-based approach. This report aims to describe and analyze leaders’ experiences of activity-based working in different organizations. For the method

Obegränsad skattskyldighet, vilket innebär att en person är skattskyldig för alla inkomster både från Sverige och utlandet, kan för en fysisk person föreligga enligt tre alternativa grunder. En av dessa grunder är väsentlig anknytning, som innebär att en från Sverige utflyttad person med vissa så kallade anknytningspunkter kan anses ha väsentlig anknytning och därmed bli obegränsat skattskyldig.

Akustisk infångning kan bli ett värdefullt verktyg i medicinsk forskning Från ett enda blod- eller urinprov kan läkare få massvis med information om en patient - information som ger ledtrådar om allt från det allmänna hälsotillståndet till eventuell förekomst av infektioner eller inflammationer, eller huruvida patienten lider av en viss sjukdom. Detta beror på att provet innehåller massor av så kaMicrofluidic systems allow for fast and precise manipulation of small volume samples in a highly controlled environment. In such a system, acoustic trapping is a powerful tool, enabling non-contact isolation of cells and microvesicles from complex media. In this technique, an ultrasonic standing wave is introduced in the microchannel. The standing wave exerts size-dependent acoustic forces on part

Hjärntumörer utgör cirka 2,5% av alla cancerdiagnoser i Sverige (2013) och femårsöverlevnaden är cirka 50%. Hjärntumörer diagnostiseras med bildtagningstekniker såsom datortomografi (CT), positronemissionstomografi (PET) och magnetkamera (MR). En MR-bild byggs upp av signaler från protoner i vatten, som är en av människokroppens vanligaste beståndsdelar. För att möjliggöra diagnostisering och klasBackground and Purpose: Dynamic glucose-enhanced (DGE) imaging is a novel technique that can be used to assess information about microvasculature by using natural sugar (D-glucose) as a biodegradable contrast agent. The method relies on chemical exchange saturation transfer (CEST). The hydroxyl protons in glucose are saturated using a selective radio-frequent pulse and will subsequently exchange w

This report aims to communicate the process and result of the master’s thesis project that was accomplished at TePe Munhygienprodukter AB, with the title Development of a dental measuring instrument. The project had a timeframe of 18 weeks and consisted to a large extent of generating a foundation for developing a product that allows for simple measuring of interdental spaces. TePe develops denta

Sverige präglas idag av en stark urbaniseringstrend, där inflyttning främst sker till våra tre storstadsregioner. Ett problem som försvårar urbaniseringen är att utbudet av bostäder inte möter den stora efterfrågan som uppstått. Byggbar mark i centrala lägen betraktas dessutom ofta som fullt ianspråktagen. På så vis har en diskussion om möjligheter att effektivisera markanvändningen uppstått. DettToday, Sweden is characterized by a strong urbanisation trend, where occupation mainly takes place in our three metropolitan regions, Stockholm, Gothenburg and Malmö. A problem that complicates the urbanisation is the fact that supply does not meet the demand of housing, which has arisen in these areas. In addition, buildable land in central areas is often considered to be fully claimed. Thus, a d

Title: To commit or not commit: An examination of employee commitment towards organizational CSR initiatives Course: BUSN39 Business Administration: Global Marketing Authors: Luis Ibbeken & Oliver Åkerman Key Words: Employee´s CSR commitment; employee´s CSR communication; organizational culture; internal CSR; internal communication; training & education; leadership; IKEA; home furnishi

Bakgrund De ledande världsekonomierna kom 2010 överens om att begränsa den globala uppvärmningen till två graders ökning jämfört med förindustriella temperaturer i hopp om att det räcker för att undvika den värsta effekten av klimatförändringar. För att nå detta mål skulle det, enligt The Intergovernmental Panel of Climate Change, krävas en absolut reducering av utsläpp med 41–72 procent till 2050Background The world’s governments agreed in 2010 to work towards limiting global warming to a two-degree warming compared to pre-industrial temperatures with the presumption that this would suffice in order to avoid the worst effects of climate change. Meeting this goal would, according to The Intergovernmental Panel on Climate Change, require a reduction of global emissions by 41–72 percent by t

Examensarbetets titel​: Text mining into customers’ minds Seminariedatum​: 4 juni 2019 Ämne/kurs​: FEKH29, Examensarbete kandidatnivå i marknadsföring, 15 högskolepoäng Författare​: Viktor Alfredsson, Jakob Ferenius & Rebin Naderi Handledare​: Burak Tunca Fem nyckelord: Varumärkesassociationer; varumärkesassociationsnätverk; text mining​; k​undrecensioner; maskininlärning Syfte​: Att utvTitle: ​Text mining into customers’ minds Seminar date: ​4 June 2019 Course: ​FEKH29​ ​Business Administration: Bachelor Degree Project in Marketing Undergraduate Level, 15 credits Authors: ​Viktor Alfredsson, Jakob Ferenius & Rebin Naderi Advisor: ​Burak Tunca Keywords: ​Brand associations; brand association networks; text mining; customer reviews; machine learning Purpose: ​To develop

The aim of this Master’s thesis is to study some of the consequences the collaboration model has brought about to public libraries in Skåne. Since the implementation of the model in 2011, the regions have obtained increased responsibilities in terms of both development work and allocation of funds to public libraries in the region. The regional cultural plan states that Kultur Skåne – The Administ

Under 2010 anmäldes 18 200 brott mot skattebrottslagen, inklusive grovt skattebrott och vådslös skatteuppgift. Skattebrott upptäcks och anmäls vanligtvis av Skatteverket eller av konkursförvaltare. I de flesta fallen förekommer även en skatteprocess i vilket det ingår skattetillägg. Skattetillägg är en särskild avgift som utgår med 40 % av den skatt som felaktigt deklarerats. Det finns ingen som In 2010 almost 18 200 crimes against the Tax Act, including gross tax crime and tax misdemeanors were reported in Sweden. Tax crimes are usually detected and reported by the Swedish Tax Agency or the liquidator. In most cases a tax procedure even occurs with the debiting of tax surcharges. Tax surcharges is a special charge added to the normal tax with 40% when the income was wrong declared. Ther

Swedish Match is a global Group of companies with a broad assortment of market-leading brands in smokeless tobacco products, cigars, pipe tobacco and lights products. The South African organization comprises of three individual companies that were acquired between 1999 and 2001. This thesis was focused on two of these three companies, Leonard Dingler and Best Blend with pipe tobacco as the most im

I den svenska arbetsmarknadsmodellen sker kollektiv reglering av arbetsvillkoren genom frivilliga självständiga förhandlingar mellanarbetsmarknadens parter. I denna modell utgör stridsåtgärder det yttersta maktmedlet för arbetstagareorganisationerna, varigenom dessa tillförsäkra sig inflytande över arbetsvillkoren och tillser att ett monopol på arbetskraften upprätthålls. Den svenska rättsordningeThe Swedish labor market model is distinguished by the fact that working conditions are, to a large extent, regulated through voluntary autonomous collective bargaining between management and labor. Strike action and other collective measures constitute the leverage with which the labor organizations can influence working conditions and maintain a monopoly on the supply of labor. To facilitate the

With a current financial crisis and a tough competitive environment, all units and departments within the companies have to keep up with the market and its demands. Every time Sandvik sells a machine to a mining company, the buyer faces the fact that they normally have to educate their operators from scratch. This, implicitly, means a period with high risks of failures and mistakes. Training with