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Modern roles for an ancient system. Intracellular Complement in the regulation of β cell function

Type 2 diabetes (T2D) is characterised by defective insulin exocytosis from the pancreatic β cells, accompanied by insulin resistance. Reduced β cells mass is often seen in T2D individuals, caused by enhanced β cells apoptosis. It is now understood that several components drive β cells dysfunction and apoptosis. These are glucose-and lipo-toxicity, ER stress, pro-inflammatory cytokines, dysfunctio

Cell Replacement Therapy for Parkinson's Disease: Potential for Circuitry Repair

The derivation of dopamine neurons from human embryonic stem cells (hESCs) now offers a promising alternative to fetal tissue for cell replacement therapy (CRT) in Parkinson´s disease (PD). Using the appropriate chemical cues in vitro, hESCs can be patterned towards bona-fide ventral midbrain (VM) DA neurons that survive, reinnervate, release DA and provide functional recovery when transplanted in

Väderskyddad produktion - Förutsättningar för lönsamhet

Titel: Väderskyddad produktion Författare: Emma Olsson & Oscar Remmerfors Handledare: Stefan Olander – Universitetslektor vid Avdelningen för Byggproduktion, Lunds Tekniska Högskola Examinator: Anne Landin – Professor vid Avdelningen för Byggproduktion, Lunds Tekniska Högskola Problemställning: • Under vilka förutsättningar kan lönsamhet uppnås vid användandet av väderskydd för nyproduktioTitle: Weather protected production Authors: Emma Olsson & Oscar Remmerfors Supervisor: Stefan Olander – Docent, Division of Construction Management, Lund University Examiner: Anne Landin – Professor, Division of Construction Management, Lund University Problem: • During which circumstances can profitability be achieved when using weather protection for the new production of residential bu

En morot från staten – Kvalificerade personaloptioner ur ett rättssäkerhetsperspektiv

Alltsedan incitamentsprogrammen introducerades i Sverige med inspiration från USA i mitten på 1900-talet har beskattningen av dem orsakat såväl tillämpningsproblem som debatt. Det handlar om de situationer där ett företag erbjuder anställda aktier i bolaget antingen i form av värdepapper eller personaloptioner. Den förra medför en rättighet direkt, medan den senare innebär en framtida rätt under fSince incentive plans first arrived to Sweden with inspiration from the U.S. in the middle of the 20th century the taxation of the programs have caused application problems as well as debate. The issue concerns situations where an employee is offered shares in the company based on securities or stock options. The employee hopes that he or she will get a piece of the profit in the future, while the

Nödvärnsrättens gränser vid angrepp mot person - Om rättspolitiska överväganden i lag och praxis

Denna uppsats undersöker gränserna för ansvarsfriheten vid våld utövat i nödvärn enligt svensk rätt och granskar de rättspolitiska överväganden som ligger till grund för gränsdragningarna i lag och praxis. Framställningen är avgränsad till angrepp mot person och behandlar inte straffmätningen vid överskriden nödvärnsrätt. En grundläggande förutsättning för ansvarsfrihet är att rätt till nödvärn fThis paper examines the Swedish law relating to the limits of violence applied when exercising self-defence and explores the prescriptive considerations underlying law and practice. The exposition is delimited to assaults against individuals and does not cover questions regarding leniency of punishment. A basic condition for freedom of responsibility is the existence of a right of self-defence. S

The Sky is the Limit - En studie av vertikal förtätning och dess projektpåverkande faktorer

Sverige präglas idag av en stark urbaniseringstrend, där inflyttning främst sker till våra tre storstadsregioner. Ett problem som försvårar urbaniseringen är att utbudet av bostäder inte möter den stora efterfrågan som uppstått. Byggbar mark i centrala lägen betraktas dessutom ofta som fullt ianspråktagen. På så vis har en diskussion om möjligheter att effektivisera markanvändningen uppstått. DettToday, Sweden is characterized by a strong urbanisation trend, where occupation mainly takes place in our three metropolitan regions, Stockholm, Gothenburg and Malmö. A problem that complicates the urbanisation is the fact that supply does not meet the demand of housing, which has arisen in these areas. In addition, buildable land in central areas is often considered to be fully claimed. Thus, a d

Tidsförlängning och ersättning vid beställarhinder enligt AB 04

Uppsatsen behandlar entreprenörens rätt till tidsförlängning och ersättning vid hinder enligt AB 04 kap. 4 § 3 p. 1 och därtill relevanta bestämmelser i AB 04. Uppsatsen syftar till att öka förståelsen för entreprenörens möjligheter att erhålla tidsförlängning och ersättning för hinder enligt AB 04 kap. 4 § 3 p. 1 och AB 04 kap. 5 § 4. Fokus ligger särskilt på, hur beställarens ansvarskrets bestämThis thesis examines the contractor’s entitlement to extension of time and compensation for delay due to impediments under AB 04, Chapter 4, Section 3, Paragraph 1, and other relevant provisions of AB 04. The purpose of the thesis is to better the understanding of the contractor’s right to obtain time extensions and compensation for delay under AB 04 Chapter 4 Section 3 Paragraph 1 and AB 04 Chapt

En diskursanalys av problemet med mäns våld mot kvinnor

Mäns våld mot kvinnor har på senaste tiden uppmärksammats, men har sedan lång tid tillbaka varit ett stort problem. Tidigare sågs det som en privat angelägenhet inom familjen medan det idag förstås som ett offentligt problem som berör flera i samhället samt flera samhällsområden. Avvikelseförklaringar till våldet har tidigare präglat förståelsen kring mäns våld mot kvinnor och frågan om våld har sMen's violence against women has recently attracted a lot of attention but has been a major problem for a long time. Previously, it was seen as a private matter within the family, while today it is understood as a public problem that affects many and several areas of society. Explanations of deviations in individuals to violence have previously characterized the understanding of men's viol

Assessing the genetic status, distribution, prey selection and conservation issues of Himalayan wolf (Canis himalayensis) in Trans-Himalayan Dolpa, Nepal

Abstract Almost nothing is known about the Tibetan wolf (Canis lupus chanco) apart from opportunistic anecdotes, notes in journals and conflict with humans. Taxonomic status of this canine has not been investigated so far for Nepal's wild population to state it as Tibetan wolf or Himalayan wolf. Furthermore, persecution of the wolf has been a major issue in the Himalayan region without any det

Implementation of Simulators at Sandvik Chile – “Practice Makes Perfect”

With a current financial crisis and a tough competitive environment, all units and departments within the companies have to keep up with the market and its demands. Every time Sandvik sells a machine to a mining company, the buyer faces the fact that they normally have to educate their operators from scratch. This, implicitly, means a period with high risks of failures and mistakes. Training with

O. Bezbozhna Archives - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law

O. Bezbozhna Archives - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of Programme Work Met

https://rwi.lu.se/author-in-pyramid-publications/o-bezbozhna/ - 2026-05-17

EU in Historic Move to Protect People of African Descent - The Raoul Wallenberg Institute of Human R

EU in Historic Move to Protect People of African Descent - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outrea

https://rwi.lu.se/news/eu-historic-move-protect-people-african-descent/ - 2026-05-17

CogSeminar: "Space and Time: Insights from Language, Temporal Diagrams and Gesture" (Emir Akbuga, LU

CogSeminar: "Space and Time: Insights from Language, Temporal Diagrams and Gesture" (Emir Akbuga, LU) | Centre for Languages and Literature 9 Apr CogSeminar: "Space and Time: Insights from Language, Temporal Diagrams and Gesture" (Emir Akbuga, LU) 9 April 2026 15:15 to 17:00 Seminar Emir Akbuga, who is currently post-doctoral researcher in English linguistics at LU, will present ongoing research o

https://www.sol.lu.se/en/the-department/calendar/event/cogseminar-space-and-time-insights-language-temporal-diagrams-and-gesture-emir-akbuga-lu/ - 2026-04-09

CogSeminar: "Space and Time: Insights from Language, Temporal Diagrams and Gesture" (Emir Akbuga, LU

CogSeminar: "Space and Time: Insights from Language, Temporal Diagrams and Gesture" (Emir Akbuga, LU) | Språk- och litteraturcentrum 9 apr CogSeminar: "Space and Time: Insights from Language, Temporal Diagrams and Gesture" (Emir Akbuga, LU) 9 april 2026 15:15 till 17:00 Seminarium Emir Akbuga, who is currently post-doctoral researcher in English linguistics at LU, will present ongoing research on

https://www.sol.lu.se/institutionen/kalendarium/evenemang/cogseminar-space-and-time-insights-language-temporal-diagrams-and-gesture-emir-akbuga-lu/ - 2026-04-09

Developing a Human Rights Library - The Raoul Wallenberg Institute of Human Rights and Humanitarian

Developing a Human Rights Library - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of Progra

https://rwi.lu.se/publications/developing-human-rights-library/ - 2026-05-16

Ashley Muza - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law

Ashley Muza - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of Programme Work Methods Focus

https://rwi.lu.se/staff/ashley-muza/ - 2026-05-16

Discussing the 2021 movie Judas and the Black Messiah at the Swedish Human Rights Film Festival - Th

Discussing the 2021 movie Judas and the Black Messiah at the Swedish Human Rights Film Festival - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Educati

https://rwi.lu.se/2021/03/29/discussing-movie-judas-and-the-black-messiah-swedish-human-rights-film-festival/ - 2026-05-16

Indonesia - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law

Indonesia - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of Programme Work Methods Focus A

https://rwi.lu.se/indonesia/ - 2026-05-16

ICMD successfully launched

ICMD successfully launched Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of Programme Work Methods Focus Areas Business and Human Rights International Humanita

https://rwi.lu.se/news/icmd-successfully-launched-at-event-attended-by-diplomatic-community-and-key-partners/ - 2026-05-16