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Effect of Complement on HIV-2 Plasma Antiviral Activity Is Intratype Specific and Potent

Human immunodeficiency virus type-2 (HIV-2) infected individuals develop immunodeficiency with a considerable delay and transmit the virus at a lower rate as compared to HIV-1 infected. Conceivably, comparative studies on immune responsiveness of the HIV-1 and HIV-2 infected hosts may help to explain differences in pathogenesis and transmission between the two types of infection. Previous studies

The Child and Adolescent Twin Study in Sweden (CATSS)

The Child and Adolescent Twin Study in Sweden (CATSS) is an ongoing longitudinal twin study targeting all twins born in Sweden since July 1, 1992. Since 2004, parents of twins are interviewed regarding the children's somatic and mental health and social environment in connection with their 9th or 12th birthdays (CATSS-9/12). By January 2010, 8,610 parental interviews concerning 17,220 twins had be

Measurement of the azimuthal anisotropy for charged particle production in root s(NN)=2.76 TeV lead-lead collisions with the ATLAS detector

Differential measurements of charged particle azimuthal anisotropy are presented for lead-lead collisions at root sNN = 2.76 TeV with the ATLAS detector at the LHC, based on an integrated luminosity of approximately 8 mu b(-1). This anisotropy is characterized via a Fourier expansion of the distribution of charged particles in azimuthal angle relative to the reaction plane, with the coefficients v

Environmental proxies of antigen exposure explain variation in immune investment better than indices of pace of life

Investment in immune defences is predicted to covary with a variety of ecologically and evolutionarily relevant axes, with pace of life and environmental antigen exposure being two examples. These axes may themselves covary directly or inversely, and such relationships can lead to conflicting predictions regarding immune investment. If pace of life shapes immune investment then, following life his

Habitat use and diet of Skylarks (Alauda arvensis) wintering in an intensive agricultural landscape of the Netherlands

In recent decades, Skylark (Alauda arvensis) populations in Europe have declined sharply due to agricultural intensification. Insufficient reproduction rates are one reason. Increased winter mortality may also be important, but studies outside the breeding season are scarce and mostly limited to the UK. We studied habitat selection of wintering Skylarks in an agricultural area in the Netherlands.

Fluorescence resonance energy transfer sensors for quantitative monitoring of pentose and disaccharide accumulation in bacteria

Background: Engineering microorganisms to improve metabolite flux requires detailed knowledge of the concentrations and flux rates of metabolites and metabolic intermediates in vivo. Fluorescence resonance energy transfer sensors represent a promising technology for measuring metabolite levels and corresponding rate changes in live cells. These sensors have been applied successfully in mammalian a

Modeling the acid-base properties of bacterial surfaces: A combined spectroscopic and potentiometric study of the gram-positive bacterium Bacillus subtilis

In this study, macroscopic and spectroscopic data were combined to develop a surface complexation model that describes the acid-base properties of Bacillus subtilis. The bacteria were freeze-dried and then resuspended in 0.1 M NaCl ionic medium. Macroscopic measurements included potentiometric acid-base titrations and electrophoretic mobility measurements. In addition, ATR-FTIR spectra of wet past

Prevalence and predictors of healthcare utilization among older people (60+): Focusing on ADL dependency and risk of depression.

The aim of this study was to investigate healthcare utilization patterns over a six-year period among older people (60+), classified as dependent/independent in Activities of Daily Living (ADL) and/or at/not at risk of depression and to identify healthcare utilization predictors. A sample (n=1402) comprising ten age cohorts aged between 60 and 96 years was drawn from the Swedish National study on

Former Male Elite Athletes Have a Higher Prevalence of Osteoarthritis and Arthroplasty in the Hip and Knee Than Expected.

BACKGROUND: Intense exercise has been reported as one risk factor for hip and knee osteoarthritis (OA). PURPOSE: This study aimed to evaluate (1) whether this is true for both former impact and nonimpact athletes, (2) if the risk of a hip or knee arthroplasty due to OA is higher than expected, and (3) if joint deterioration is associated with knee injuries. STUDY DESIGN: Cohort study; Level of evi

Sydvästsvensk a-genitiv - en levande relikt

In modern standard Swedish genitive is marked by -s, which, according to the standard analyses, is a phrasal clitic, viz. [mannen på gatan]s åsikt (man on street-s opinion). In dialects in parts of Småland, Halland, and Västergötland a variant on -a or -e, here called a-genitive, is used, primarily on proper names, viz. Erik-a bil (Erik-gen car) ‘Erik’s car’, a form that should be compared to the

Mechanisms of Dopamine D1 Receptor-Mediated ERK1/2 Activation in the Parkinsonian Striatum and Their Modulation by Metabotropic Glutamate Receptor Type 5.

In animal models of Parkinson's disease, striatal overactivation of ERK1/2 via dopamine (DA) D1 receptors is the hallmark of a supersensitive molecular response associated with dyskinetic behaviors. Here we investigate the pathways involved in D1 receptor-dependent ERK1/2 activation using acute striatal slices from rodents with unilateral 6-hydroxydopamine (6-OHDA) lesions. Application of the dopa

Fire evacuation in underground transportation systems: a review of accidents and research

A review of literature related to fire evacuation in underground transportation systems, e.g., tunnels and subway stations, was carried out with the objectives (1) to identify a theoretical framework that can help understand of human behaviour in the event of a fire in underground transportation systems, (2) to use the theoretical framework to analyse and to identify problems related to fire evacu

Mirakel, mysterier och moraliteter. Från puritanism till New Age - en religionshistorisk studie av Helen Shucman och A Course in Miracles

A Course in Miracles (ACIM) is a spiritual teaching that was said to be channelled by Helen Shucman during 1965-1972. Shucman received what she described as an inner dictation, which she wrote down in shorthand. Her collegue and friend; William Thetford was then copy-typing the text. It came to comprise of around 1,200 pages of text, and is presented as a program of self-tuition, aimed to change a

Phylogeography of a Habitat Specialist with High Dispersal Capability: The Savi’s Warbler Locustella luscinioides

In order to describe the influence of Pleistocene glaciations on the genetic structure and demography of a highly mobile, but specialized, passerine, the Savi’s Warbler (Locustella luscinioides), mitochondrial DNA sequences (ND2) and microsatellites were analysed in c.330 individuals of 17 breeding and two wintering populations. Phylogenetic, population genetics and coalescent methods were used to

Harmonic decomposition of two particle angular correlations in Pb-Pb collisions at root s(NN)=2.76 TeV

Angular correlations between unidentified charged trigger (t) and associated (a) particles are measured by the ALICE experiment in Pb-Pb collisions at root s(NN) = 2.76 TeV for transverse momenta 0.25 < p(T)(t,a) < 15 GeV/c, where p(T)(t) > p(T)(a). The shapes of the pair correlation distributions are studied in a variety of collision centrality classes between 0 and 50% of the total hadronic cros

Diatom floristic change and lake paleoproduction as evidence of recent eutrophication in shallow lakes of the midwestern USA

Intensive agricultural practices can dramatically change the landscape, thereby increasing the concentrations and rates at which nutrients are delivered to aquatic ecosystems. In the United States, concerns about accelerating rates of lake eutrophication related to increases in nutrient loading require a method of quantifying ecological changes that have occurred since European settlement. Because

Social Media and Green Marketing Strategies: An exploratory study of selected leading companies

Social media has become the most popular communication channel. Large amounts of information flows are being exchanged between users. The information shared on social media is seen as more reliable than the information found on traditional media. Companies have already incorporated social media as one of their communication channels. However, the evolution of social media has occurred in such a br

Street Women Vendors and their Empowerment in the Public and Private Sphere: a Study on the Street Women Vendors in Gilan Province- Iran

The factors behind the struggle for women’s empowerment in Iran are a combination of social, religio-cultural and traditional constraints. These have been institutionalized through the legal and legislative system, as well as the informal traditional practices in the public and private spheres. The Iranian legislative apparatus which directly and indirectly poses constraints on women’s presence in

On cascading failure models and robustness metrics in power networks

Network research tries to give solutions within several areas, beginning from social interconnections, logistic problems, virus spreading, supply networks...etc. Some metrics have been developed in order to predict blackouts and improve power grid robustness. Metrics use part of the grid information seeking weakness without simulating the blackout process. On the other hand, simulation models unfo