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Objective: The objectives were to determine the prevalence of meeting criteria for symptoms suggestive of early osteoarthritis (OA) after anterior cruciate ligament reconstruction (ACLR) and to characterize the longitudinal changes in these symptoms during the first two years post-ACLR. Methods: We analyzed data from 10,231 patients aged 14 to 40 years in the New Zealand ACL Registry who completed

Chemicals such as bisphenols, parabens and triclosan are endocrine disrupting chemicals. They are used in a wide variety of consumer products, making human exposure to those chemicals widespread. In the present study, levels of three bisphenols (bisphenol A, F and S), 7 parabens (methyl-, ethyl-, isopropyl-, propyl-, isobutyl-, butyl-, benzyl paraben) and triclosan were measured in first morning v

IntroductionNon-beta-haemolytic streptococci are among the most common causative agents of infective endocarditis (IE). Patients with a heart valve prosthesis (HVP) have a high risk of IE. We aimed to determine the risk for IE in patients with HVP and non-beta-haemolytic streptococcal bacteraemia (NBHSB), and to study NBHSB relapse depending on treatment duration.MethodAdults with HVP and NBHSB 20

In elite sport, athletes and staff may face unique personal- and sports-related stressors that can both bolster and undermine their mental health. Meanwhile, toughness, perfectionism, stigma, and unwanted attention can serve as exacerbating factors and help-seeking deterrents. Two outpatient psychiatric clinics specializing in elite sport and health have been established in Sweden, including one i

This study scans six decades of film history in search for video images, the imaginaries within which they are framed, and (taking cues from the archaeological methods of Friedrich Kittler and Michel Foucault) their technical, historical, and institutional conditions of existence. The British experimental science fiction film Anti-Clock (Jane Arden and Jack Bond, 1979) revolves around a video devi

BACKGROUND: Lung cancer remains one of the most challenging diseases to treat due to its heterogeneity. Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) mutations are genetic drivers in numerous cancer types including lung adenocarcinoma (LUAD). Despite recent advances in KRAS-targeted therapies, treatment resistance and limited therapeutic options necessitate advanced preclinical models, such as

BackgroundEarly initiation of breastfeeding, defined as breastfeeding within one hour of birth, halves the risk of neonatal mortality, establishing it as a crucial outcome component in various interventions implemented across South Asian countries. However, the overall effect of these interventions remain unexamined. Therefore, this study seeks to address this knowledge gap by evaluating the overa

Background: It is important to identify and evaluate cardiovascular risk factors at an early stage to address them accordingly. Among the younger population, the metabolic syndrome is less common than in older ages. However, each separate metabolic risk factor still has an additive effect on cardiovascular risk factor burden. Non-metabolic risk factors that occur in the younger population include

Introduction: Thyroid cancer (TC) is diagnosed in several histological types which differ in their clinical characteristics and survival. We aim to describe how they influence TC survival in Sweden. Methods: Cancer data were obtained from the Swedish cancer registry between years 1999 and 2018, and these were used to analyze relative survival. Results: Relative survival for all TC improved when an

Background: High breast density is an independent risk factor for breast cancer and decreases the sensitivity of mammography. This systematic review synthesizes the international clinical guidelines and the evidence base for screening and supplemental screening recommendations in women with dense breasts. Methods: A systematic search of CINHAL, Embase, and Medline databases was performed in August

Introduction: The evidence-base for the impact of participating in the arts for different aspects of health and wellbeing is growing. Arts on Prescription has gained increasing recognition as a method for fostering connections among individuals and communities, however, to date no systematic review of the impact on individual health and wellbeing has been conducted. This review aims to provide an

Background: Stickler syndrome is a hereditary disorder of collagen tissues causing ocular, auditory, orofacial, and joint manifestations. Ocular findings typically include vitreous degeneration, high myopia, retinal detachment, and cataract. Many subjects demonstrate sensorineural or conductive hearing loss. The inheritance is autosomal dominant with mutations in COL2A1, COL11A1, or COL11A2 or aut

Massive bird migration across continents and seas is one of the most spectacular phenomena in nature, involving billions of birds annually. In the autumn, most birds on migration are juveniles migrating for the first time while adults are repeating their migrations. Migration syndrome in individual bird migrants involves multiple behavioural, morphological and physiological adaptations, and migrat

Introduction: The use of medications in the general population has increased over time. Information on active metabolite concentrations for common drugs in the general population is limited. Recent advances in metabolomic technologies have made high-throughput profiling of many active metabolites in large epidemiological cohorts increasingly feasible.Aim: 1. Prospective assessment of the proportio

Background: Type 1 diabetes (T1D) is a major risk factor for cardiovascular disease (CVD). Matrix metalloproteinase-14 (MMP-14) is involved in the development of atherosclerosis and CVD. The main aim was to explore the associations between MMP-14 and selected inflammatory and metabolic variables, CVD, depression, physical activity, smoking and medication in patients with T1D. The secondary aim was

BACKGROUND: The role of coagulase-negative staphylococci (CNS) in bacteremias continues to be controversial. Until the 1970s, CNS were mostly recognized as contaminants, being part of the cutaneous flora. Since then, several studies have reported increasing incidence and severity of infections due to CNS.PURPOSE: To review the literature concerning the epidemiology of CNS bacteremia in the United

Background: Job stress and burnout are common among healthcare professionals, and nurses in particular. In addition to the heavy workload and lack of recourses, nurses are also confronted with emotionally intense situations associated with illness and suffering, which require empathic abilities. Although empathy is one of the core values in nursing, if not properly balanced it can also have detrim

Purpose: To analyze the relationship between rates of false positive (FP) responses and standard automated perimetry results. Design: Prospective multicenter cross-sectional study. Methods: One hundred twenty-six patients with manifest or suspect glaucoma were tested with Swedish Interactive Thresholding Algorithm (SITA) Standard, SITA Fast, and SITA Faster at each of 2 visits. We calculated inter