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Proteins constitute a major component of living cells and are essential to their function. Sometimes proteins misfold or aggregate in abnormal ways, which can give rise to diseases. Amyloids are a special type of highly ordered protein aggregates made of long intermolecular beta-sheets stacked into fibrils. Formation of amyloids is associated with many diseases, especially diseases related to neur
The feasibility of willow short rotation coppice (SRC) for energy production as a revaluation tool for severely radiocaesium-contaminated land was studied. The effects of crop age, clone and soil type on the radiocaesium. levels in the wood were assessed following sampling in 14 existing willow SRC fields, planted on radiocaesium-contaminated land in Sweden following Chernobyl deposition. There wa
OBJECTIVE: To identify all new cases of systemic lupus erythematosus (SLE) within a defined area in Southern Sweden with validated methods of retrieval, and to compare 2 cohorts assembled during 1981-86 and 1987-91. METHODS: The catchment area, the health care district of Lund-Orup, had during 1981-91 a mean adult population (> 15 years of age) of 172,300 individuals. During 1987-91 we identified
To examine the efficacy and safety of vildagliptin vs. glimepiride as add-on therapy to metformin in patients with type 2 diabetes mellitus in a 52-week interim analysis of a large, randomized, double-blind, multicentre study. The primary objective was to demonstrate non-inferiority of vildagliptin vs. glimepiride in glycosylated haemoglobin (HbA(1c)) reduction at week 52. Patients inadequately co
Needle stimulation (acupuncture) has recently been shown to increase blood flow in the tibialis anterior muscle and overlying skin in healthy subjects (HS) and patients with fibromyalgia (FM). The aim of the present study was to examine the effect of needle stimulation on local blood flow in the trapezius muscle and overlying skin in HS and two groups of patients suffering from chronic pain in the
Popular Abstract in Swedish Avhandlingen innehåller tre empiriska studier som analyserar hur livsmedelsmarknaden påverkas av åtgärder för att fördjupa den europeiska ekonomiska integrationen. Fokus är på det svenska EU-medlemskap och det kontinuerliga arbetet med att harmonisera livsmedelslagstiftningen. Det senare har stor relevans för livsmedelsmarknaden eftersom det har funnits och fortfarande This thesis consists of three papers, all of which deal with the effects of deepening European integration on the food and beverage industry and market. The focus is on the period after Swedish EU membership in 1995. The last two papers use firm data and focus on the Swedish food and beverage industry, an industry which is an interesting case study as it was considered to be protected from foreign
Background: Stroke is one of the major causes of disability in the adult population and represents a heavy social and economic burden. Currently available therapeutic tools to support the recovery of impaired brain functions are quite limited. Animal studies have demonstrated that neuronal replacement and partial reconstruction of neural circuitry or modulation of the recovery process is possible
The subject of this study is the re-intensified dispute between rhetoric and philosophy in the times of the Second Sophistic. The focus of our investigation has been on two authors of this period who have left behind treatises the explicit purpose of which is to attack or defend rhetoric: Sextus Empiricus who is sharply criticising rhetoric and Aelius Aristides who is defending it. Our purpose has
1. The survey has mainly concentrated on the following items: the false alarm problem, the problem of the fire not being detected due to the fact that pre-fire heating and ventilation dominate flow inside the compartment, a description of detector sensitivity to fire signatures. engineering design methods for the siting of detectors. 2. The statistical as well as practical experience suggests that
The work presented in this thesis is based on time-resolved x-ray diffraction studies of InSb (111) samples. The experiments were carried out using a pump-probe configuration using short laser pulses as the pump and x-rays as the probe. Laser excitation leads to the formation of a strain pulse that propagates through the sample. The strain pulse gives rise to coherent longitudinal, acoustic phonon
The Internet, apart from being a fascinating field of study in its own right, has opened up new possibilities for scholars to get news, gather data, connect with informants, and in general stay updated on rapidly changing developments in Chinese society. Social media have added yet another dimension as it enables researchers to catch up with events and public debates as they unfold and get valuabl
Three methods are presented to calculate the load distribution in a chain drive containing two sprockets and one chain. The rollers, which are in contact with the sprockets, can move along the tooth flanks and their positions are given by force equilibrium. Since the positions of the rollers, and thereby also the load distribution, depend on the two connecting spans, it has been necessary to inclu
Popular Abstract in Swedish Intensifieringen av jordbruket under de senaste sextio åren har resulterat i en dramatisk produktionsökning av framförallt spannmål. Denna typ av produktion, speciellt det mest intensiva s.k. industrijordbruket, har samtidigt också resulterat i en ohållbar degradering av ekosystemen och miljön, till exempel förlust av biologisk mångfald, utsläpp av växthusgaser, förgiftSeveral studies have found that organic farms support higher biodiversity, but results vary between studies such that some also show no or even negative effects. There can be many reasons why studies comparing organic and conventional farming show conflicting results. The efficacy of organic farming can depend on focal taxa, landscape context, study scale and the proportion of organically managed
Semiconductor nanowires are nanoscale objects formed by bottom-up synthesis. In recent years their unique properties have been exploited in fields such as electronics, photonics, sensors and the life sciences. In this work, the epitaxial growth of nanowires and their applications were studied. Heteroepitaxial growth of III-V nanowires on silicon substrates was demonstrated. This may enable direct
This thesis includes one introductory chapter and three independent papers. The first paper adds to the broad literature regarding the effect of alcohol consumption on educational attainment. Given that no consensus exists in the literature regarding this paper adds to the literature by analyzing the effect of alcohol consumption on educational attainment using a life cycle approach. In addition
Little is known the evolution of ‘yes’ and ‘no’ in human language, and in this paper, an attempt is made to make a first step in revealing how our ancestor came up with these words. Our analysis starts with Proto-Uralic, and then we compare its developmental path to other languages in the Indo-European family.
It has been documented that in Proto-Uralic (ca. 4,000 BC) there existed e ‘no’, but
Low-dimensional III-V semiconductor nanoscale structures grown by epitaxial processes have emerged as a new class of materials with great promise for various device applications. This thesis describes explorations into the heteroepitaxial growth of III-V semiconductor materials in combination with other III-V materials and in combination with the commonly used Si material, in both thin layer and n
Title: Mediating tools in the practice of choir directors – a study of working approaches and actions in choral conducting with children and youth. Abstract: In Sweden, approximately 5 % of the population sing in a choir or a singing group which means that about 500 000 people plus a number of choral conductors regularly meet in choir related practices. The aim of the present study is to describ
Sepsis induced by intestinal perforation is a life-threatening illness and is a frequent cause of leukocyte-mediated lung injury. Although antimicrobial therapy has been the central clinical strategy for these patients, the survival rates in such patients are still very low because of their impaired host defense mechanisms. Therefore, control of amplified leukocyte recruitment in the lung may be a
At the end of the eighteenth century, Edward Gibbon described the antiquarian scholars of previous generations as men of “profound learning and easy faith.” His exemplar was the Swedish polymath Olof Rudbeck, who in a series of frantic and combative tomes sought to portray Sweden as the model for Plato’s Atlantis and the seething cultural cauldron from which Western civilization had emerged. A Pil
