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MicroRNA-379 Modulates Prostate-Specific Antigen Expression Through Targeting the Androgen Receptor in Prostate Cancer

Background: MicroRNA-379 (miR-379) has been reported to play a tumour-suppressing role in several cancer types. Our previous work demonstrated that miR-379 overexpression attenuates the metastatic spread of prostate cancer (PCa) both in vitro and in vivo. However, the underlying mechanisms remain poorly understood. Methods: To elucidate the mechanisms by which miR-379 affects metastases, we perf

Barn, men ändå vuxna: straff och ansvar i förändring - En rättshistorisk analys av den straffrättsliga synen på barn som lagöverträdare i ljuset av förslaget om sänkt straffbarhetsålder

De senaste åren har präglats av en repressiv kriminalpolitik vilket kommit till uttryck i reformer som påverkat särbehandlingen av barn och unga la-göverträdare. I juli 2023 tillsattes utredningen SOU 2025:11 Straffbarhets-åldern med uppdrag att överväga och föreslå en sänkning av straffbarhets-åldern. Utredningens arbete resulterade till en sänkning av straffbarhetsål-dern till 14 år vid allvarliIn recent years, Swedish criminal policy has become increasingly repressive, a development reflected in reforms that have affected the special treatment of children and young offenders. In July 2023, the inquiry SOU 2025:11 The Age of Criminal Responsibility was appointed with the task of considering and proposing a lowering of the age of criminal responsibility. The inquiry resulted in a proposal

Periodic Inversion Domains on Step-Flow Surfaces of N-Polar GaN Grown on m-Plane Offcut 4H-SiC(0001̅)

Understanding the atomic-scale interfaces in advanced semiconductor heterostructures is essential for controlling defects, optimizing material properties, and ensuring device reliability. In this work, we present a comprehensive study of the atomic structure at Al(Ga)N interfaces in N-polar GaN high-electron-mobility transistor structures (HEMTs) via aberration-corrected annular dark field scannin

Sorting Particles by Deterministic Lateral Displacement : Effects of Shape and Size from Single Particles to Clusters

This thesis investigates particle sorting in deterministic lateral displacement (DLD) microfluidic devices, with a focus on how particle size and shape influence sorting behavior. A broad range of synthetic and biological particles were studied, including polystyrene particles, fabricated silicon-based structures, and bacterial samples with diverse physical properties.While DLD has traditionally b

A new sample of massive B-type contact binary candidates from the OGLE survey of the Magellanic Clouds

Context. Massive contact binaries (CBs) are crucial objects for understanding close binary evolution and stellar mergers. Study of these objects has been hampered by a scarcity of observed systems, particularly of B-type systems which are expected to dominate this class. Aims. We bridge this observational gap by mining a large sample of massive CB candidates from the OGLE-IV database, potentially

From the Inside Out : Municipal Strategies for Governing Industrial and Urban Symbiosis

Industrial and urban symbiosis (IUS) is increasingly promoted as a means to reduce resource use, lowerenvironmental impacts, and support local sustainability transitions. Municipalities are often assigned akey role in facilitating such arrangements, yet research has primarily focused on inter-firm collaborationand external coordination, paying limited attention to how municipal organizations thems

Spectroscopy of core-excited molecules and exploration of the induced dynamics

This thesis investigates core excited electronic states of molecules in gas phase. In particular, the resonanttransitions of ionised molecules, the site-selectivity surrounding Auger-Meitner decay, and the nuclear dynamicsthat may follow core excitation and ionisation.Background: Fundamental understanding of molecules and ions lay the groundwork for all future applicativescience and production. Fo

TIA1 Mutant Mouse Model Exhibits Motor Deficits and Neurodegenerative Characteristics of Amyotrophic Lateral Sclerosis

Highlights: What are the main findings? Motor neuron death in TIA1Δ mice occurs prior to detectable TDP-43 phosphorylation. TDP-43 accumulates and mislocalizes in the absence of phosphorylation in TIA1Δ mice, which may represent a speculative pre-aggregation-like disease stage. What are the implications of the main findings? The TIA1Δ mouse model provides a unique tool to dissect early, phosphoryl

Ex vivo and in vivo immunomodulation in acute lung injury and lung transplantation

Lung transplantation (LTx) remains the only curative treatment for patients with end-stage lung disease, yet long-term outcomes remain inferior to those of other solid organ transplantations, with a 5-year survival below 70%. Major contributors to this limited outcome include primary graft dysfunction (PGD), the leading cause of early mortality, chronic lung allograft dysfunction (CLAD), and low u

Bis(pyridin-2-ylmethyl)amine-grafted poly(aryl alkylene)s with enhanced chemical stability and acid-base interactions for high-temperature proton exchange membranes

Developing high-temperature proton exchange membranes (HT-PEMs) that simultaneously achieve high proton conductivity, strong phosphoric acid (PA) retention, and long-term chemical stability remains a major challenge, particularly due to PA-induced plasticization and radical-induced oxidative degradation. Here, we develop a side-chain engineering strategy to decouple PA-binding sites from the polym

A Better World Can Exist: Hindu Folklores and the Decolonial Imaginaries of a Degrowth Society.

Degrowth has emerged as a critical framework challenging the dominant assumption that continuous economic growth is necessary for human progress and well-being. While degrowth offers important critiques of capitalist accumulation, ecological destruction, and growth-oriented development, the field has largely been shaped by Western intellectual traditions and policy discourses. It has also yet to e

The Bittersweet Taste of Sensemaking: How Consultants Make Sense of Generative AI in Relation to their Professional Identity

Title: The bittersweet taste of sensemaking: How consultants make sense of Generative AI in relation to their professional identity Course: BUSN49, Degree Project in Managing People, Knowledge and Change – Master Level Authors: Gloria Julia Glupe and Merryl Frances Nathanie Meka Supervisor: Sverre Spoelstra, Associate Professor, Lund University, Sweden Purpose: This study focuses on how consult

8aVer2MOD_Transgression LTH R1

8aVer2MOD_Transgression LTH R1 LTH:s 13:e Pedagogiska Inspirationskonferens, 4 december 2025 Abstract—Transgressive learning has gained scholarly interest as a way of enabling learners to question and defy norms that perpetuate unsustainability. However, transgression can also be risky and calls for responsible teaching able to identify and prevent such risks. This paper asks How transgressive lea

https://www.lth.se/fileadmin/cee/genombrottet/konferens2025/D4a_Lasselin_etal.pdf - 2026-06-09

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TRVN11 Required Reading The reading list is valid for one (1) year after completion of the course Centre fo r Theology and Re l ig ious Stud ies Required reading for TRV N11 Religious Roots of Europe: The Emergence of Judaism, Christianity and Islam, 15 ECTS credits, Fall Semester 2026 as approved by the Director of Studies on 4 June 2026 Books to be obtained by the student Berkey, Jonathan, The F

https://www.ht.lu.se/media/utbildning/dokument/kurser/TRVN11/20262/TRV_N11_Required_Reading.pdf - 2026-06-11

Weiss_Riewerts

Weiss_Riewerts The 2nd EuroSoTL conference, June 8-9 2017, Lund, Sweden Decoding Research-Oriented Teaching: Make Research Processes Explicit and Identify Research Competencies P. Weiss, and K. Riewerts, Bielefeld University ABSTRACT: In recent years, research-oriented teaching has been revived as a prominent approach in higher education. E.g., the Boyer Commission Report has called for the US tha

https://konferens.ht.lu.se/fileadmin/_migrated/content_uploads/Weiss_Riewerts.pdf - 2026-06-20

V. Saskevich Archives - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law

V. Saskevich Archives - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of Programme Work Met

https://rwi.lu.se/author-in-pyramid-publications/v-saskevich/ - 2026-06-23

Humanitarian Visas Can Be Highly Effective - The Raoul Wallenberg Institute of Human Rights and Huma

Humanitarian Visas Can Be Highly Effective - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation

https://rwi.lu.se/publications/humanitarian-visas-policy-brief-2/ - 2026-06-23

Raoul Wallenberg Insitute and Humanitarian Law Archives - The Raoul Wallenberg Institute of Human Ri

Raoul Wallenberg Insitute and Humanitarian Law Archives - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreac

https://rwi.lu.se/tag/raoul-wallenberg-insitute-and-humanitarian-law/ - 2026-06-23

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Saco-rådet i Umeå kommun ÅRSMÖTESPROTOKOLL 2021-03-31 Plats och tid Onsdag den 31 mars 2021, Digitalt via TEAMS, kl. 18.00 – 19.00 Närvarande Saco-medlemmar: Carina Lidgren Heimersson Tichaona Dumba Maphosa P-O Backlund Birgitta Larsson Joakim Åsberg Nina Stenbacka Lena Svedjehed Karin Berggren Marcus Forsvall Ellen Stenberg § 1 Årsmötets öppnande SACO-rådets ordförande Joakim Åsberg förklarade SA

https://www.saco.se/globalassets/lokala-akademikerforeningar/kommun-och-region/umea-kommun/dokument/saco-protokoll-arsmote-2021.docx - 2026-06-23