Filtyp
The proteoglycan NG2 plays a major role in proliferation, migration, and differentiation of pericytes and NG2 cells in the brain. We have previously reported decreased NG2 levels in cerebrospinal fluid (CSF) from patients with Alzheimer's disease (AD) and a relationship between NG2 and AD biomarkers in these patients. To further investigate whether alterations in NG2 is specific to AD pathology, w
A role for the immune system in the pathogenesis of Parkinson's Disease (PD) has previously been suggested. A recent genome-wide association (GWA) study identified an association between one single nucleotide polymorphism (SNP) in the human leucocyte antigen (HLA) region (HLA-DRA rs3129882) and PD in a population of American patients with European ancestry. In that study, the minor rs3129882 allel
Objective: To redesign the current assembly process of the Ektorp Sofa from IKEA in order to improve cycle times, quality levels and to reduce, if possible, costs associated with manufacturing, production times and materials. IKEA wants to increase either the productivity or the quality standard of the Ektorp Sofa by simplifying the processes involved in the construction of the sofa and modernizin
Teachers are both controlling agents and controlled subjects, in any educational system. Educational research has approached this dual role from a variety of practical and theoretical angles, the most notable perhaps being the perspective of teacher autonomy as it is negotiated between, simply speaking, structure and agency. This essay urges to more critically illuminate the relationship between o
Cell-cycle inhibition has yet to offer a generally effective approach to cancer treatment, but a full evaluation of different combinations of cell-cycle inhibitors has not been evaluated. Cyclin A2, a core component of the cell cycle, is often aberrantly expressed in cancer where it may impact cell proliferation. In this study, we investigated the role of cyclin A2 in tumorigenesis using a conditi
PURPOSE: The partial volume effect (PVE) is an important source of bias in brain perfusion measurements. The impact of tissue PVEs in perfusion measurements with dynamic susceptibility contrast MRI (DSC-MRI) has not yet been well established. The purpose of this study was to suggest a partial volume correction (PVC) approach for DSC-MRI and to study how PVC affects DSC-MRI perfusion results.METHOD
What makes people affectively polarized? Affective polarization is based on the idea that partisanship can be a social identity leading to polarization in the form of intergroup distancing between the own party and the other parties. In this study, we argue that perceived threats from an outgroup can spur affective polarization. To investigate this, we use the issue of immigration, often framed as
nstrumentation, control and automation (ICA) in wastewater treatment systems is now an established and recognised area of technology in the profession. There are obvious incentives for ICA, not the least from an economic point of view. Plants are also becoming increasingly complex which necessitates automation and control. Instrumentation, Control and Automation in Wastewater Systems summarizes t
Over the past few decades new cities have appeared around the world in undeveloped areas. And although development has expanded significantly and become bolder and more innovative, the above-average scale at which the countries of the Persian Gulf are growing stands one level above the rest. The United Arab Emirates obtained independence in 1971 with a GDP of 6.5 billion Dirhams (US$ 1.6 billion);
In the 1990s, Japanese energy regulators were concerned by the fact that new generations of energy using appliances and products no longer displayed successive use-phase energy efficiency improvements, such as those that characterised product development in Japan after the 1970s oil crises. Therefore, in 1999, Japan incepted its Top Runner programme, designed to rejuvenate the lost momentum. Sever
Many courses within higher education are assessed by “faculty standards” sometimes based on the implicit assumption that “it has always been like this, therefore it is the best”. Selecting and combining different assessment modes in an effective manner for a particular course are central issues. The process does not always entail a simple and straight-forward decision making. The main purpose of t
There is today a need of better prediction of part geometry regarding industrial products by simulations. There is a need for better prediction of material inflow, stresses and strains and final geometry. One way to solve this could be by using a more advanced friction model. Today a zero order friction model (Coulomb friction) is normally used. By using a friction model of higher order the fricti
Information technology is a central phenomenon in modern society. It is widely used in a variety of settings and commercial firms use it for a variety of purposes. It could be an Internet application, a manufacturing system, office support software, electronic data interchange or something else, applied in order to create economic benefits through improvements of operative work tasks and business
Popular Abstract in Swedish Optoelektronik genomgår för närvarande en otrolig utveckling, inte minst på grund av de senaste årtiondenas kommersialisering och utveckling av hemelektronik som kompaktdiskar och digitalkameror. Denna utveckling har drivit en blomstrande global tillväxt för optoelektroniska företag som varje år utvidgar sina erbjudanden av optiska komponenter i hård konkurrens. UtvecklThe present thesis describes a number of aspects of modern electro-optical measurement technology also known as bio-photonics; this includes instrumentation, applications, sample interaction and data interpretation. The methods employed operate over several domains, and light measurements are discretized both in intensity, space, angle, time, polarization and energy. Mainly the spectral domain is
The thesis considers the effects of electron correlation by studying the two opposite limits of atoms in the ground state and atoms in strong laser pulses. Computational methods and theoretical approaches differ significantly due to the different physical processes that are studied in these two cases. The thesis has an introductory chapter with a brief discussion of the problem of describing elec
Popular Abstract in Swedish Samhällets produktion av avfall är ett ständigt pågående problem. Tidigare metodik för att ta hand om avfallet genom att deponera det på soptippar håller på att förändras. Genom beslut inom EU har det kommit krav på sortering av avfallet vilket har lett till att hushållsavfall inte längre kommer att få deponeras. Ett sätt att ta hand om avfall är att förbränna avfallet Baling of MSW has been extensively used in Sweden and other countries for the storage of energy (biomass for energy) for incineration and production of either and or electricity and heat. Baling is performed in two principally different ways, leading to cylindrical- or rectangular bales. This work has focused on various parameters during the storage of MSW. The first parameters investigated were g
Popular Abstract in Swedish Det finns alltmer bevis för att både genetiska och tidiga miljömässiga faktorer spelar en väsentlig roll i uppkomsten av schizofreni genom att påverka tidig neuroutveckling. För att kunna analysera betydelsen av tidig neuroutvecklingsavvikelse för uppkomst av schizofreni, har vi studerat tidiga traumata, dvs obstetriska komplikationer (OCs), samt dysmorfogenes, dvs lindTo measure the importance of early neurodevelopmental disturbance for schizophrenia, early trauma and dysmorphogenesis (i.e. obstetric complications (OCs), minor physical anomalies (MPAs), head circumference (HC) and dermatoglyphic characteristics) were studied in relationship to adult neurodysfunction (i.e. neurological abnormality (NA), neurocognitive dysfunction (NCGD), tardive dyskinesia (TD)
