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Background: Population-based empirical information to inform health care professionals working with children with spina bifida currently is lacking. Spina bifida is a highly complex condition that not only affects mobility but many additional aspects of life. We have developed a pilot project that focuses on a broad range of domains: Surgeries, development and learning, nutrition and physical grow
The recent influx of migrants and asylum seekers in Europe has drawn our attention towards the future of Schengen and European border politics. In 2014-2015 a European collaborative project called Turnstone (partly funded by the European commission) was implemented to increase control of European borders in the Baltic Sea area and to diminish trans-boundary criminality. The purpose of the project
Female moths emit sex pheromones to lure a mate. In this thesis I examined the transcriptomes of female moth pheromone glands in order to identify genes encoding proteins involved in pheromone production. Two cDNA-libraries were constructed from Agrotis segetum (Noctuidae) pheromone glands and the remaining body tissue, respectively. The libraries were sampled and sequenced. A total of 707 unigene
he basic idea of the particular way of understanding mental phenomena that has inspired the "cognitive revolution" is that, as a result of certain relatively recent intellectual and technological innovations, informed theorists now possess a more powerfully insightful comparison or model for mind than was available to any thinkers in the past. The model in question is that of software, or the list
Hemiparasitic plants accumulate nutrients in their leaves and therefore produce high-quality litter with faster decomposition and nutrient release rates compared to non-parasitic litter. Higher levels of plant-available nitrogen (N) in the presence of hemiparasitic plants have been attributed to this 'litter effect', but effects on N dynamics in the soil remain unstudied. We tested the hypothesis
This thesis presents two sources of extreme ultraviolet (XUV) radiation based on high-order harmonic generation (HHG) in gases. The sources were developed for experiments requiring high-flux harmonic beams or HHG pulses at high-repetition rate. These were used experimentally to image nano-scale objects. The high-flux HHG source was used for digital in-line holography, and the high-repetition rate
The evidence concerning the possible association between physical activity and the risk of prostate cancer is inconsistent and additional data are needed. We examined the association between risk of prostate cancer and physical activity at work and in leisure time in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. In our study, including 127,923 men aged 20-97 years
We have in a population-based setting evaluated biochemical markers of bone metabolism in 328 women, aged 40-80 years, and related it to contents of bone mineral measurements and the retrospective and prospective presence of fracture. The participants were recruited from the city population files. Serum samples for analysis of osteocalcin (Oc), procollagen I carboxy-terminal extension peptide (PIC
The apparent permeability index is widely used as part of a general screening process to study drug absorption, and is routinely obtained from in vitro or ex vivo experiments. A classical example, widely used in the pharmaceutical industry, is the in vitro Caco-2 cell culture model. The index is defined as the initial flux of compound through the membrane (normalized by membrane surface area and d
Declining biological production as a part of an ongoing land degradation process is considered a severe environmental problem in the dry northern and northwestern regions of China. The aim of this study is to develop and adapt a satellite data-driven gross primary production model called Lund University light use efficiency model (LULUE) to temperate conditions in order to map gross primary produc
Ferric uptake regulator (Fur) and Fur-like proteins form an important family of transcriptional regulators in many bacterial species. In this work we have characterized a Fur-like protein, the peroxide regulator PerR, in an M1 serotype of Streptococcus pyogenes. To determine the role of PerR in S. pyogenes, we inactivated the gene by allelic replacement. PerR-deficient bacteria showed 48% reductio
In adipocytes, phosphorylation and activation of PDE3B is a key event in the antilipolytic action of insulin. The role of PDE4, another PDE present in adipocytes, is not yet known. In this work we investigate the role of PDE3B and PDE4 in insulin-induced glucose uptake, GLUT-4 translocation and lipogenesis. Inhibition of PDE3 (OPC3911, milrinone) but not PDE4 (RO 20-1724) lowered insulin-induced g
Rationale: Atrial fibrillation (AF) increases the risk of stroke and it can be reduced by treatment with warfarin. Some patients consider that warfarin is a stressful treatment with undesired effects and the perceived barriers include unwillingness to take it. Knowledge of patients resisting warfarin treatment may be useful for the potential threat to maintaining shared decision-making in the cons
The development of tolerant microorganisms is needed for the efficient fermentation of inhibitory lignocellulose hydrolysates. In the current work, the fermentation performance of six selected strains of Saccharomyces cerevisiae in dilute-acid spruce hydrolysate was compared using two different modes of fermentation; either single pulse addition of hydrolysate to exponentially growing cells or con
Backgrounds. A focus on psychiatric rehabilitation in order to support recovery among persons with severe mental illness (SMI) has been given great attention in research and mental health policy, but less impact on clinical practice. Despite the potential impact of psychiatric rehabilitation on health and wellbeing, there is a lack of research regarding the model called the Psychiatric Rehabilitat
The 17 Sustainable Development Goals (SDGs), adopted in 2015, aim to engage the planet into general efforts to end all forms of poverty, fight inequalities and tackle climate change worldwide. It consists in an original attempt to engage all groups and individuals by setting targets to be met over the incoming 15 years. One of the biggest innovations of the SDGs has been the consideration of the p
ISO 14001 är en internationell miljöcertifiering för företag som vill arbeta mer effektivt med sina miljöpåverkande aspekter. Även om det inte går att fastställa att ISO 14001-certifierade företag faktiskt minskar sin miljöpåverkan, visar tidigare studier att certifierade företag uppfyller miljölagkrav bättre än icke-certifierade företag. Ett av kraven som ställs på företag när de certifieras är aEven though there is little evidence that ISO 14001 certified companies actually reduce their environmental impact, previous studies show that certified companies comply to environmental regulatory demands better than non-certified companies. The purpose of this study is to examine the regulatory compliance of ISO 14001 certified companies in the south of Sweden. The empirical data is based on ins
The fact that educational buildings are places where the majority of us spend most of our formative years, their design plays an important part in improving the education level and well-being of society. A number of changes have been made to the traditional design of these buildings in the last few decades and the old education system, where the teacher solely acts as an informer and the children
Uppsatsen handlar om sekretessmarkering som omfattar barn då sekretessmarkeringen är tillkommen med anledning av barnets andra förälder/vårdnadshavare. Uppgifter om hot och våld är i studien inte styrkta genom dom. Arbetet rör sig inom fälten familjerätt – offentlig rätt. Syftet med uppsatsen är att undersöka effekter och konsekvenser av en sekretessmarkering. Är gemensam vårdnad och umgänge möjliThe thesis is examining classified personal data within the national registration, ”Sekretessmarkering”, when it includes children and what consequences that might have in a legal process concerning custody. The thesis is within the fields of family law - public law. The purpose of the thesis is to examine the effects and consequences of such a classification. Is joint custody and access rights po
