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”Being ill was the easy part” : exploring cancer survivors’ reactions to perceived challenges in engaging with primary healthcare

Purpose: Cancer survivors experience barriers to primary healthcare (PHC) services. The aim was to explore reactions to and opinions about perceived challenges associated with PHC access and quality among cancer survivors in Sweden, including how they have acted to adapt to challenges. Methods: Five semi-structured focus group interviews were conducted with cancer survivors (n = 20) from Skåne, Sw

Virtual reality-assisted assessment of paranoid ideation in forensic psychiatric inpatients : A mixed-methods pilot study

Background: Reliable and valid assessment of paranoia is important in forensic psychiatry for providing adequate care. VR technology may add to current assessment procedures, as it enables observation within realistic (social) situations resembling the complexity of everyday life. VR constitutes a promising tool within forensics, due to the restricted nature of forensic psychiatric hospitals and e

Towards carbon neutrality : Transition pathways for the Chinese ethylene industry

Ethylene is one of the most important products in the emissions-intensive petrochemical industry. Decarbonizing the ethylene industry is thus important for achieving global carbon neutrality. This study is the first to explore future long-term zero-emissions production pathways for the ethylene industry in China, the world's biggest ethylene producer. An optimization model was built in the context

Violation of onco-surgical principles is associated with survival outcomes in upper tract urothelial carcinomas after radical nephroureterectomy

OBJECTIVE: Disease recurrence, particularly intravesical recurrence (IVR) after radical nephroureterectomy (RNU) for upper tract urothelial carcinoma (UTUC), is common. We investigated whether violations of onco-surgical principles before or during RNU, collectively referred to as surgical violation (SV), were associated with survival outcomes. Material and methods: Data from a consecutive series

A Reception of Pauline Ideas Shaped by a Jewish Milieu : The Case of the Pseudo-Clementine Homilies

This essay focuses on the reception of Pauline ideas in the Pseudo-Clementine Homilies, commonly dated to the early fourth century. At first, the claim that the Pseudo-Clementine Homilies contain Pauline ideas may seem surprising, since the Homilies are commonly considered “Jewish Christian” and thus anti-Pauline. However, new readings of Paul generated by the “Paul within Judaism” perspective, al

Cluster Formation Induced by Local Dielectric Saturation in Restricted Primitive Model Electrolytes

Experiments using the Surface Force Apparatus (SFA) have found anomalously long-ranged charge–charge underscreening in concentrated salt solutions. Meanwhile, theory and simulations have suggested ion clustering to be a possible origin of this behavior. The popular Restricted Primitive Model of electrolyte solutions, in which the solvent is represented by a uniform relative dielectric constant, εr

Exploring the Early Molecular Pathogenesis of Osteoarthritis Using Differential Network Analysis of Human Synovial Fluid

The molecular mechanisms that drive the onset and development of osteoarthritis (OA) remain largely unknown. In this exploratory study, we used a proteomic platform (SOMAscan assay) to measure the relative abundance of more than 6000 proteins in synovial fluid (SF) from knees of human donors with healthy or mildly degenerated tissues, and knees with late-stage OA from patients undergoing knee repl

Stochastic method based on copulas for predicting severe road traffic interactions

A major difficulty in assessing road traffic safety is the scarcity of historical accident data. xxThis is a common problem in contexts where a certain level of safety has been reached or where exposure is low, such as mixed traffic conditions with different levels of transport automation. Recent studies have demonstrated how severe interactions between road users and/or road users and infrastruct

Quantum dot source-drain transport response at microwave frequencies

Quantum dots are frequently used as charge-sensitive devices in low-temperature experiments to probe electric charge in mesoscopic conductors where the current running through the quantum dot is modulated by the nearby charge environment. Recent experiments have operated these detectors using reflectometry measurements up to gigahertz frequencies rather than probing the low-frequency current throu

Exploring patient safety risk in an emergency ward for substance use through a mixed-method analysis

Background:There is limited knowledge of how psychiatric patient safety measures can detect and understand risk as an emergent property within a healthcare system. Overcrowding poses a risk for patient safety in psychiatric emergency wards and is associated with increased mortality and violence. This paper aims to explore patterns of risk emergence in a psychiatric ward and provide insights into t

Improving glacio-hydrological model calibration and model performance in cold regions using satellite snow cover data

Hydrological modeling realism is a central research question in hydrological studies. However, it is still a common practice to calibrate hydrological models using streamflow as a single hydrological variable, which can lead to large parameter uncertainty in hydrological simulations. To address this issue, this study employed a multi-variable calibration framework to reduce parameter uncertainty i

Socioeconomic factors and outcome after repair and reconstruction of digital and major nerve trunk injuries in the upper limb

Peripheral nerve injuries in the upper limb can lead to substantial disability and pain. We aimed to assess how socioeconomic factors affect outcomes after repaired or reconstructed digital or major nerve trunk injuries in the upper limb. We identified 670 individuals, who underwent surgical nerve repair or reconstruction using sensory nerve autografts, in the Swedish National Quality Registry for

T-matrix computations of light scattering by red blood cells

The electromagnetic far field, as well as the near field, originating from light interaction with a red blood cell ~RBC! volume-equivalent spheroid, was analyzed by utilizing the T-matrix theory. This method is a powerful tool that makes it possible to study the influence of cell shape on the angular distribution ofscattered light. General observations were that the three-dimensional shape, as wel

Frequent mismatch-repair defects link prostate cancer to Lynch syndrome

BACKGROUND: A possible role for prostate cancer in Lynch syndrome has been debated based on observations of mismatch-repair defective tumors and reports of an increased risk of prostate cancer in mutation carriers. Potential inclusion of prostate cancer in the Lynch syndrome tumor spectrum is relevant for family classification, risk estimates and surveillance recommendations in mutation carriers.M

An eco-evolutionary model for demographic and phenological responses in migratory birds

Many migratory birds have changed their timing of arrival at breeding grounds in response to recent climate change. Understanding the adaptive value and the demographic consequences of these shifts are key challenges. To address these questions we extend previous models of phenological adaptation to climate change under territory competition to include feedback from population dynamics, winter sur

Humidity Sensing in Drosophila

Environmental humidity influences the fitness and geographic distribution of all animals [1]. Insects in particular use humidity cues to navigate the environment, and previous work suggests the existence of specific sensory mechanisms to detect favorable humidity ranges [2-5]. Yet, the molecular and cellular basis of humidity sensing (hygrosensation) remains poorly understood. Here we describe gen

Mechanical symptoms as an indication for knee arthroscopy in patients with degenerative meniscus tear : a prospective cohort study

OBJECTIVE: According to prevailing consensus, patients with mechanical symptoms are those considered to most likely benefit from arthroscopic surgery. The aim of this study was to determine the value of using patients' pre-operative self-reports of mechanical symptoms as a justification surgery in patients with degenerative meniscus tear/knee disease.DESIGN: Pragmatic prospective cohort of 900 con

Managing end-users and their requirements in the construction process

The effective management of end-users and their requirements in construction projects can bring a number of benefits, for example more satisfied and less critical end-users in terms of both the product and project. Building occupants are however continually changing and with that their needs. It is thereby a challenge to understand what brings value for both known and unknown end-users. More over

An exploration of leisure shopping in retail store environments: Illuminating meanings, manifoldness and dynamics in consumers shopping experiences

Shopping has since long been recognized as a possible source of enjoyment. It has been argued that consumers of today devote ever more of their spare time to shopping. Within the domain of marketing, scholars have been successful in outlining consumers' motives for engaging in shopping as a leisure-time enjoyment. Minor attention has however been devoted to explorations of how or why such shopping