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Use of 4 Open-Ended Text Responses to Help Identify People at Risk of Gaming Disorder : Preregistered Development and Usability Study Using Natural Language Processing

Background: Words are a natural way to describe mental states in humans, while numerical values are a convenient and effective way to carry out quantitative psychological research. With the growing interest of researchers in gaming disorder, the number of screening tools is growing. However, they all require self-quantification of mental states. The rapid development of natural language processing

Enhancing Knock Detection and Combustion Diagnostics : A Machine Learning Approach with Ion Current Sensors

Achieving robust and efficient control of internal combustion engines is critical for meeting stringent environmental regulations and reducing greenhouse gas emissions. Natural gas engines, in particular, offer significant potential for cleaner energy but present unique challenges due to variations in fuel composition and combustion dynamics.This thesis investigates novel methods for improving com

Characterization of Non-Wide-Sense Stationarity for Distributed Massive MIMO Channels

Distributed massive multiple-input multiple-output (MIMO) communication is envisioned as one of the key paradigms of future MIMO systems. To investigate non-wide-sense stationarities (non-WSSs) in distributed massive MIMO channels, this paper first presents an indoor channel measurement campaign, where distributed arrays with a total of 128 elements were implemented. Then relying on the correlatio

Tuning Interactions in Correlated Electron Systems: From Two-Band Superconductivity to Quasi-1D Spin Chains

Neutron scattering techniques have been employed to investigate two key areas of condensed matter physics: superconductivity and quantum magnetism. The experimental studies span two distinct areas: two-band superconductors, where we explore the interplay between superconducting anisotropy and vortex structure, and quasi-one-dimensional (quasi-1D) spin chains, where we investigate the magnetic exci

Behavioral and neural aspects of serial dependence in facial identity

Den visuella omvärlden kan vara dynamisk och föränderlig vilket skapar otydlighet i sensorisk information. Dessutom genererar hjärnans neurala aktivitet ”brus” som bidrar till denna otydlighet. Trots dessa svårigheter kan det visuella systemet i hjärnan bearbeta denna otydliga information och skapa en kontinuerlig och stabil visuell upplevelse, vilket låter oss navigera i omvärlden med trygghet. E

The PEPSI exoplanet transit survey (PETS) I : Investigating the presence of a silicate atmosphere on the super-earth 55 Cnc e

The study of exoplanets and especially their atmospheres can reveal key insights on their evolution by identifying specific atmospheric species. For such atmospheric investigations, high-resolution transmission spectroscopy has shown great success, especially for Jupiter-type planets. Towards the atmospheric characterization of smaller planets, the super-Earth exoplanet 55 Cnc e is one of the most

Insight into the dimer dissociation process of the Chromobacterium violaceum (S)-selective amine transaminase

One of the main factors hampering the implementation in industry of transaminase-based processes for the synthesis of enantiopure amines is their often low storage and operational stability. Our still limited understanding of the inactivation processes undermining the stability of wild-type transaminases represents an obstacle to improving their stability through enzyme engineering. In this paper

Energy transfer in multi-funnel systems quantitatively assessed by two-dimensional polarization imaging and single funnel approximation : From single molecules to ensembles

Two-dimensional polarization imaging (2D POLIM) is an experimental method where correlations between fluorescence excitation- and fluorescence emission-polarization properties are measured. One way to analyze 2D POLIM data is to apply a so-called single funnel approximation (SFA). The SFA allows for quantitative assessment of energy transfer between chromophores with identical spectra [homo-FRET (

Locating Cities and their Governments in Multi-Level Sustainability Governance

Cities and their governments are increasingly recognized as important actors in global sustainability governance. With the adoption of the 2030 Agenda for Sustainable Development, their role in the global endeavor to foster sustainability has once again been put in the spotlight. Several scholars have highlighted pioneering local strategies and policies to implement the Sustainable Development Goa

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Active generative cooling based on supercritical hydrocarbon fuel is regarded as one of the most promising methods for scramjet thermal management. A large eddy simulation method is used to explore the transient change law of the initial flow, and heat transfer behaviors of supercritical hydrocarbon fuel is in rectangular channels. An oscillation effect can be proved in the convective heat transfe

A Brake System Coefficient of Friction Estimation Using 3D Friction Maps

The coefficient of friction (COF) is one of the core factors in the evaluation of brake system performance. It is challenging to predict the COF, since it is strongly influenced by several parameters such as contact pressure (p), slip rate (v) and temperature (T) that depend on the driving conditions. There is a need for better models to describe how the brake friction varies under different drivi

Access-Based Consumption in the Built Environment: Sharing Spaces

The pressing need to implement a more circular economy has led to advancements in the research field. In the spatial context, sharing spaces and access-over-ownership models have the potential to mitigate the detrimental environmental impacts of space use. This study aims to adapt an existing theoretical framework on access-based consumption to the spatial context. We utilise a qualitative case st

Search, save and share: family historians’ engagement practices with digital platforms

Alongside established heritage institutions, family historians are central figures in the ecosystem of digital heritage, both as contributors to and users of digitized historical sources. With that in mind, this research aims for a wide examination of family historians’ engagement with the broader selection of available digital platforms, providing knowledge about how and why they choose to use on

Structural basis of activation and antagonism of receptor signaling mediated by interleukin-27

Interleukin-27 (IL-27) uniquely assembles p28 and EBI3 subunits to a heterodimeric cytokine that signals via IL-27Rα and gp130. To provide the structural framework for receptor activation by IL-27 and its emerging therapeutic targeting, we report here crystal structures of mouse IL-27 in complex with IL-27Rα and of human IL-27 in complex with SRF388, a monoclonal antibody undergoing clinical trial

Reproductive outcome after early miscarriage : comparing vaginal misoprostol treatment with expectant management in a planned secondary analysis of a randomized controlled trial

Objective: To compare the reproductive outcome after early miscarriage between women managed expectantly and those treated with vaginal misoprostol. Methods: This study was a planned secondary analysis of data collected prospectively in a randomized controlled trial comparing expectant management with vaginal misoprostol treatment (single dose of 800 µg) in women with early embryonic or anembryoni

Quality of Life among Next of Kin of Frail Older People in Nursing Homes : An Interview Study after an Educational Intervention concerning Palliative Care

One cornerstone of palliative care is improving the family’s quality of life (QoL). The principles of palliative care have not been sufficiently applied in nursing homes. The aim of this study was to investigate the experiences of QoL of next of kin of frail older persons in nursing homes after an educational intervention concerning palliative care. This qualitative interview study with 37 next of

Kenya and Uganda

In this chapter, we describe the post-colonial history of higher education (HE) in Kenya and Uganda to explain why domestic doctoral education is still at a young stage in both countries. We present their national HE frameworks, and thereafter focus on local policy and practice in two public universities: Makerere University in Uganda and the University of Nairobi in Kenya. Our results are informe

Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes

Multi-nucleotide variants (MNVs), defined as two or more nearby variants existing on the same haplotype in an individual, are a clinically and biologically important class of genetic variation. However, existing tools typically do not accurately classify MNVs, and understanding of their mutational origins remains limited. Here, we systematically survey MNVs in 125,748 whole exomes and 15,708 whole