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Robot-assisted approach to cervical cancer (RACC) : An international multi-center, open-label randomized controlled trial

Background Radical hysterectomy with pelvic lymphadenectomy represents the standard treatment for early-stage cervical cancer. Results from a recent randomized controlled trial demonstrate that minimally invasive surgery is inferior to laparotomy with regards to disease-free and overall survival. Primary Objective To investigate the oncologic safety of robot-assisted surgery for early-stage cervic

Spatial analysis of HIV-TB co-clustering in Uganda

BACKGROUND: Tuberculosis (TB) is the leading cause of death for individuals infected with Human immunodeficiency virus (HIV). Conversely, HIV is the most important risk factor in the progression of TB from the latent to the active status. In order to manage this double epidemic situation, an integrated approach that includes HIV management in TB patients was proposed by the World Health Organizati

Patient Reported Outcomes in Cleft Lip and Palate

Aim: Patient reported outcome measures (PROMs) quantify various domains of health related quality of life (HRQOL) from the patient perspective. The overall aim of this thesis was to investigate patient reported outcomes (PROs) in patients with cleft lip and/or palate (CL/P). Method: PROs were investigated in the CL/P population with PROMs and interviews. Health care professional (HCP) experience o

Archiving the Spaces of Anxiety : From the Burrow to the Peach Colony

Archiving the Spaces of Anxiety exhibition in Beijing, China curated by Shuyu ChenArchiving the Spaces of Anxiety takes its form from a transitional path that links Kafka’s unfinished short story The Burrow (1923–1924) and Wu Li’s painting White Cloud and Green Mountain (1668), by looking into a set of intertwining relations between the external space that surrounds us, and the internal space that

Cataract patients in a defined Swedish population 1986-1990

Popular Abstract in Swedish Denne populationstudie om kataraktkirurgi strakte sig over en pre- og peroperativ fase med indsamling af data i perioden 1986-1990. Den postoperative dataindsamling i denne redegørelse dækker perioden 1986-1992. Epidemiologiske forhold belyses i det første og syvende arbejde. Anatomiske og især refraktive forhold bliver belyst i den andet og tredje publikation. Det fjerThere has been a striking increase in the number of cataract operations in the referral region of the Lund Health Care District during 1986 through 1990, in 1990 reaching 3.6 per 1000 inhabitants. Different preoperative, intraoperative and postoperative variables and observations were registered and analysed for 5878 consecutive cataract cases operated in the period studied. Women predominate in t

Volcanic Aerosols in the Upper Troposphere and Stratosphere – Aircraft- and Satellite-Based Observations

Volcanic eruptions are the largest source of variability in the stratospheric particle concentration as they inject SO2 that is subsequently converted into sulphate particles. No major perturbation of the stratospheric aerosol load has been observed since the large eruption of Pinatubo in 1991, but several moderate eruptions after 2000 have caused deviations from stratospheric background condition

Radiomics-Derived Brain Age Predicts Functional Outcome after Acute Ischemic Stroke

Background and ObjectivesWhile chronological age is one of the most influential determinants of poststroke outcomes, little is known of the impact of neuroimaging-derived biological "brain age."We hypothesized that radiomics analyses of T2-FLAIR images texture would provide brain age estimates and that advanced brain age of patients with stroke will be associated with cardiovascular risk factors a

Polyploid evolution in the European orchid genus Nigritella: evidence from DNA fingerprinting

The genus Nigritella (Orchidaceae-Orchidinae) is a complex of species at four different ploidy levels. Fourteen taxa at species or subspecies level have been distinguished. The triploid N. nigra ssp. nigra is endemic to Scandinavia, whereas the remaining taxa are confined to different mountain regions in Central and Southern Europe. The polyploids are of hybrid origin and have arisen from taxa at

The Arts of Editing Medieval Greek and Latin : a Casebook

With the triumph of the codex, medieval literature became more deeply hermeneutic in character. A vast range of texts, in various languages and genres, were not only copied with the commentaries and glosses of ancient tradition, but also underwent continuous reworking and transformation. Indeed, the very act of transcribing texts into a manuscript was often an incentive to rewrite them. This pract

Tricuspid valve flow measurement using a deep learning framework for automated valve-tracking 2D phase contrast

Purpose: Tricuspid valve flow velocities are challenging to measure with cardiovascular MR, as the rapidly moving valvular plane prohibits direct flow evaluation, but they are vitally important to diastolic function evaluation. We developed an automated valve-tracking 2D method for measuring flow through the dynamic tricuspid valve. Methods: Nine healthy subjects and 2 patients were imaged. The ap

ETHICS AND PUBLIC HEALTH INTERVENTIONS.

Programmatic vaccination and screening are the reasons for this thesis. The practice of public health incorporating medicine’s cognitive contents along with contributions from other fields of human activities is basically a moral enterprise. It is important that limitations from the whole continuum of these interventions are recognized to retain credibility. The changing demands resulting from the

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As far back as the Early Modern period, Swedish Reformation centenaries were exploited politically. Instead of Martin Luther, the liberation from Denmark (1521) and the Declaration of the Swedish Reformation (1593) were celebrated. From 1817 and 1830, Reformation centenaries were celebrated in a more continental form, but the Confessio Augustana-Celebration was combined with the clebration of Swed

Genomic and Molecular Aspects of Mature Human B Cells

This thesis covers aspects of the mature human B cell and its different guises on its way to become a fully differentiated antibody forming plasma cell (AFC), the key player in the humoral immune system. The understanding of the complex molecular mechanisms taking place in the B cell, as it first encounters antigen, enters the germinal center (GC) reaction, giving rise to memory cells and plasma c

Obstetric outcome after in vitro fertilization with single or double embryo transfer

BACKGROUND: IVF children, including singletons, are known to have a poorer obstetric outcome than children born after spontaneous conception. With a broad introduction of single embryo transfer (SET), this scenario might change. This study compares the obstetric outcome after IVF with SET, elective SET (eSET), non elective SET (non-eSET) and double embryo transfer (DET) with outcomes in the genera

Quantitative Analysis of Immune Response and Erythropoiesis during Rodent Malarial Infection

Malarial infection is associated with complex immune and erythropoietic responses in the host. A quantitative understanding of these processes is essential to help inform malaria therapy and for the design of effective vaccines. In this study, we use a statistical model-fitting approach to investigate the immune and erythropoietic responses in Plasmodium chabaudi infections of mice. Three mouse ph

Examination of laboratory-generated coated soot particles: An overview of the LACIS Experiment in November (LExNo) campaign

In the suite of laboratory measurements described here and in companion articles we deal with the hygroscopic growth and activation behavior of coated soot particles synthesized to mimic those of an atmospheric aerosol originating from biomass combustion. The investigations were performed during the measurement campaign LACIS Experiment in November (LExNo) which took place at the Leipzig Aerosol C

Mass transport of contaminated soil released into surface water by landslides (Göta River, SW Sweden)

Landslides of contaminated soil into surface water represent an overlooked exposure pathway that has not been addressed properly in existing risk analysis for landslide hazard, contaminated land, or river basin management. A landslide of contaminated soil into surface water implies an instantaneous exposure of the water to the soil, dramatically changing the prerequisites for the mobilisation and

Prevalence and Severity of Undetected Manifest Glaucoma: Results from the Early Manifest Glaucoma Trial Screening.

PURPOSE: To estimate the prevalence and severity of undetected glaucoma in the population. DESIGN: Cross-sectional study. PARTICIPANTS: A total of 32 918 subjects aged 55 to 79 years from Malmö, Sweden, who were screened between 1992 and 1997. All subjects in the screened age groups living in the catchment area, and for whom there were no recent records at the Malmö University Hospital Ophthalmolo