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Almost Global Consensus on the n-Sphere

This paper establishes novel results regarding the global convergence properties of a large class of consensus protocols for multiagent systems that evolve in continuous time on the n-dimensional unit sphere or n-sphere. For any connected, undirected graph and all \in \mathbb{N} \backslash \lbrace 1\rbrace$, each protocol in said class is shown to yield almost global consensus. The feedback laws a

European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation

Atopic dermatitis (AD) is a common inflammatory skin condition and prior genome-wide association studies (GWAS) have identified 71 associated loci. In the current study we conducted the largest AD GWAS to date (discovery N = 1,086,394, replication N = 3,604,027), combining previously reported cohorts with additional available data. We identified 81 loci (29 novel) in the European-only analysis (wh

HapZipper : sharing HapMap populations just got easier

The rapidly growing amount of genomic sequence data being generated and made publicly available necessitate the development of new data storage and archiving methods. The vast amount of data being shared and manipulated also create new challenges for network resources. Thus, developing advanced data compression techniques is becoming an integral part of data production and analysis. The HapMap pro

The Contested realities of the Circular Economy

We acknowledge that the CE is not one ‘thing’, but, rather, could be seen as an ‘empty signifier’ (Valenzuela and Böhm 2017), which allows for a whole range of interpretations and approaches to be bundled together under the term ‘circular economy’. Indeed, the CE is said to have 114 definitions (Kirchherr et al. 2017), which implies that academics and practitioners do not necessarily agree on prec

Cross comparison and prognostic assessment of breast cancer multigene signatures in a large population-based contemporary clinical series

Multigene expression signatures provide a molecular subdivision of early breast cancer associated with patient outcome. A gap remains in the validation of such signatures in clinical treatment groups of patients within population-based cohorts of unselected primary breast cancer representing contemporary disease stages and current treatments. A cohort of 3520 resectable breast cancers with RNA seq

Two-Way Gaze Sharing in Remote Teaching

On-line teaching situations where a tutor and their students are remote from each other mean that contact between them is reduced compared with teaching in a classroom. We report an initial study of two-way gaze sharing between a tutor and a group of students, who were in different locations. A 45-min class consisted of an introductory lecture followed by an exercise in using two software tools, o

Thermal stress analysis of solid oxide fuel cells with chromium poisoning cathodes

Chromium(Cr) poisoning of the traditional LSM cathode is one of the most critical issues that accounts for instability of solid oxide fuel cells (SOFCs). The poisoning course will introduce alien species in the cathode active regions and it causes phase change and structure deformation, reducing the sites for electrochemical reactions. A 3D model is thus developed by coupling the computational flu

Late Paleoproterozoic mafic magmatism and the Kalahari craton during Columbia assembly

The 1.87–1.84 Ga Black Hills dike swarm of the Kalahari craton (South Africa) is coeval with several regional magmatic provinces used here to resolve the craton’s position during Columbia assembly. We report a new 1850 ± 4 Ma (U-Pb isotope dilution–thermal ionization mass spectrometry [ID-TIMS] on baddeleyite) crystallization age for one dike and new paleomagnetic data for 34 dikes of which 8 have

Neural-Network-Assisted UE Localization Using Radio-Channel Fingerprints in LTE Networks

In this paper, a novel fingerprint-based localization technique is proposed, which is applicable for positioning user equipments (UEs) in cellular communication networks such as the long-term-evolution (LTE) system. This technique utilizes a unique mapping between the characteristics of a radio channel formulated as a fingerprint vector and a geographical location. A feature-extraction algorithm i

Sweden : Minority government as the norm

Swedish coalition politics is markedly influenced both by a historically strong emphasis on near-unidimensional political conflict along the left-right economic dimension, the once-dominant position of the Social Democrats, and a negative parliamentarism system. These factors have contributed to most governments formed during the post-World War Two period comprising a minority of seats in parliame

Public procurement a vehicle for change

In this chapter, we explore not only the challenges with public procurement, but also how public organization can turn procurement into a useful tool that can help develop quality in public services provision and delivery. There is a belief that public procurement can be an instrument for change. The public sector is a large procurer, and the idea is that if public procurers demand better products

Human iPS-Derived Astroglia from a Stable Neural Precursor State Show Improved Functionality Compared with Conventional Astrocytic Models

In vivo studies of human brain cellular function face challenging ethical and practical difficulties. Animal models are typically used but display distinct cellular differences. One specific example is astrocytes, recently recognized for contribution to neurological diseases and a link to the genetic risk factor apolipoprotein E (APOE). Current astrocytic in vitro models are questioned for lack of

Stigma matters in ending tuberculosis : Nationwide survey of stigma in Ethiopia

BACKGROUND: Tuberculosis (TB) affects, and claims the lives of, millions every year. Despite efforts to find and treat TB, about four million cases were missed globally in 2017. Barriers to accessing health care, inadequate health-seeking behavior of the community, poor socioeconomic conditions, and stigma are major determinants of this gap. Unfortunately, TB-related stigma remains unexplored in E

Heterogeneous Returns to Medical Innovations

This paper sets up a quasi-experiment to estimate both total and heterogeneous impacts of medical innovations on the individual’s economic outcomes for a comprehensive set of around 90 health conditions. The rich administrative panel data for Sweden covering more than 1 million individuals combined with disease-specific data on new molecular entities and patents granted in healthcare have allowed

Salbutamol for transient tachypnea of the newborn

BACKGROUND: Transient tachypnea of the newborn is characterized by tachypnea and signs of respiratory distress. Transient tachypnea typically appears within the first two hours of life in term and late preterm newborns. Although transient tachypnea of the newborn is usually a self-limited condition, it is associated with wheezing syndromes in late childhood. The rationale for the use of salbutamol