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Urine sediments from 20 patients with urinary bladder carcinoma, and from 11 healthy individuals were investigated for their content of Lea and Leb active glycolipids. The investigation was restricted to blood group phenotype Le (a-b+). All individuals exhibited both Lea- and Leb-active glycolipids. In healthy individuals the ratio Lea/Leb was less than 1 in 10 out of 11 cases, whereas in patients
Human papillomaviruses (HPVs) exist as more than 100 distinct types. Variants of HPVs appear to be common findings while HPV subtypes have been considered rare. New information about subtypes has recently been reported by us. Our characterisation of subtype HPV38b[FA125] and the identification of several HPV isolates representing putative subtypes have considerably extended the knowledge about thi
The cycloruthenation of 2-phenylimidazole (phim) by [Ru(6-C6H6)(-Cl)Cl]2 in acetonitrile in the presence of NaOH has been carried out. The unstable intermediate [Ru(phim)(MeCN)4]PF6 formed has been converted into the complexes [Ru(phim)(4,4′-Me2bpy)(MeCN)2]PF6 (2) and [Ru(phim)(LL)2]PF6 (3, LL=phen (a), bpy, 4,4′-Me2bpy), which were characterized by the mass-spectrometry, 1H-NMR spectroscopy, UV–v
This study was conducted to explore treatment and disease-related effects on health-related quality of life (HRQoL) in patients with aggressive lymphoma, to identify predictors for impaired long-term HRQoL, and to analyze the prognostic value of pretreatment HRQoL. Ninety-five patients with aggressive lymphoma, constituting a subset of a randomized multicenter trial comparing CHOP and MACOP-B, ent
Objective:To determine whether the combined intervention of 50 000 IU vitamin A administered together with Bacille Calmette-Guerin (BCG) vaccination at birth was associated with adverse events, in particular bulging fontanels and adverse reactions to BCG.Subjects/Methods:From an ongoing trial, 2145 infants randomized to 50 000 IU vitamin A or placebo with BCG vaccination were recruited. Adverse ev
Reaction between a mixture of cis-trans-[PtCl2(SMe2)(2)] and 1 eqiv. AsPh3 in chloroform gives Cis-[PtCl2(SMe2)(AsPh3)] crystallizing in P2(1)/n with a = 10.397(2), b = 14.876(3), c = 13.956(3) Angstrom, beta = 90.86(3)degrees and Z = 4. Selected geometrical parameters are Pt-As 2.3531(10), Pt-S 2.262(2), Pt-Cl (trans to S) 2.301(2), Pt-Cl (trans to As) 2.328(2) Angstrom and S-Pt-As 88.85(6), S-Pt
Energy metabolism at the level of any particular tissue is tightly regulated by hormones, neurotransmitters and cytokines in order to maintain overall energy homeostasis. Any dysfunctions in energy metabolism may lead to more or less severe consequences, with obesity and type 2 diabetes being the most prevalent ones. Type 2 diabetes is characterized by defective insulin secretion (?-cell dysfuncti
Popular Abstract in Swedish Syftet med studien är att bestämma de faktorer som påverkar eleverna då de löser matematiska problem i årskurserna 4-9 i grundskolan. Metoden, som använts, består i en analys av lösningarna till 25 problem, som getts i var och en av årskurserna. Några av problemen har varit desamma i alla årskurserna och ungefär 100 elever har deltagit i varje årskurs. Genom att undersöThe purpose of this study is to identify the factors influencing pupils when they individually solve problems in mathematics in grades 4-9 in the compulsory school (ages: 10-16 years). The method that has been used is an analyses of the solutions of 25 problems given to each grade. Some of the problems were the same in all grades and about 100 pupils participated in each grade. Through an examinat
The most malignant brain tumour, glioblastoma multiforme (GBM), has an utterly bad prognosis. In spite of all available therapy, the mean survival time is less than a year. In the unique BRIGTT project (Brain Immuno Gene Tumour Therapy), patients at the Dept of Neurosurgery. Lund University Hospital, are immunised with their own glioma cells, which have been transfected with the immunostimulatory
Four strains of lactic acid bacteria were used as pure or mixed cultures to investigate the texture-promoting capacity and exopolysaccharides (EPS) formation in three different oat-based, non-dairy milk products, Adavena G40, Adavena M40 (both with a dry matter content of 20%) and Mill Milk (with a dry matter content of 10%). Viscosity was measured at two different shear rates during 2 min of shea
The effects of 2,3-butanedione monoxime (BDM) were studied in smooth muscle fibres from guinea pig taenia coli. In intact muscle, active force during contractions induced by high-K+ was inhibited by about 10% in 1 mM BDM and by approximately 70% in 10 mM BDM. Intracellular [Ca2+] during contraction, measured with the fura-2 technique, was reduced in the presence of BDM. The reduction in force and
Background. Some autoimmune and chronic inflammatory disorders are associated with increased risks of non-Hodgkin lymphoma (NHL). Because different NHL subtypes develop at different stages of lymphocyte differentiation, associations of autoimmune and inflammatory disorders with specific NHL subtypes could lead to a better understanding of lymphomagenic mechanisms. Methods: In a population-based ca
Popular Abstract in Swedish Moraxella catarrhalis är en human luftvägsbakterie som ofta koloniserar de övre luftvägarna och som orsakar mellanöroninfektion hos barn. Bakterien associeras även med bihåleinfektion, laryngit och nedre luftvägsinfektioner främst hos vuxna med underliggande sjukdomar som kronisk obstruktiv lugninflammation. Forskningen fokuserar främst på moraxellas ytexponerade antigeMoraxella catarrhalis is now an established human pathogen that frequently colonizes the upper respiratory tract causing most importantly otitis media in children. It has also been associated with sinusitis, laryngitis and lower respiratory tract infections in adults with predisposing conditions such as chronic obstructive pulmonary disease (COPD). Current research mainly focuses on surface antige
Human polyclonal and monoclonal antibodies against pathogens and toxins are potentially useful in the treatment of various diseases. A number of human monoclonal antibodies with protective capacity in vitro have been established by conventional hybridoma technology. However, with the development of phage-display technology, the possibility of specifically tailoring antigen-binding properties has i
The Rh blood group antigen e is of high incidence and has many epitopes. Partial expression may occur, more commonly in black persons. Individuals with e variant phenotypes can make antibodies to epitopes they lack. While some of these antibodies may be specific for an antigen, e.g., hrB, others, like anti-Rh17 (anti-Hro), show broader specificity, compatible only with D-- and Rhnull red blood cel
Popular Abstract in Swedish Cancer är en komplex och heterogen sjukdom där celler har börjat växa okontrollerat och denna sjukdom är idag ett stort hälsoproblem. På grund av diffusa symptom upptäcks cancern ofta i ett sent stadium. Otillräcklig kunskap om olika fenotyper hindrar utvecklingen av riktad behandling och patienter svarar därför väldigt olika på en given behandling. Denna avhandling ärCancer is a complex and heterogeneous disease where cells have started to grow uncontrolled and this disease remains a major health problem. Because of diffuse symptoms it often presents at a late stage. Insufficient understanding of the different phenotypes hinders the development of targeted therapeutics and consequently patients show a diverse range of responses to a given treatment. This thes
Popular Abstract in Swedish Tillväxtintentioner och kommunikativ praktik Strategiskt entreprenörskap vid företagsutveckling Denna avhandling fokuserar på entreprenörers “will and skill”, d.v.s. viljan och den kunskap och färdighet som entreprenören har vid start och utveckling av ett företag. Med vilja avses entreprenörens tillväxtintention och med kunskap och färdighet avses kommunikationen mellThis thesis focuses on the “will and skill” of individuals who take part in activities of running a business. The aspect of “will” is studied in terms of growth intentions and the aspect of “skill” is studied in terms of communicative practices. The overall purpose is to explore how entrepreneurs think and talk about growth and how they act in their communicative practices to express their growth
