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OBJECTIVE: Aortic aneurysm size is a critical determinant of the need for intervention, yet the maximal diameter will often vary depending on the modality and method of measurement. We aimed to define the relationship between commonly used computed tomography (CT) measurement techniques and those based on current reporting standards and to compare the values obtained with diameter measured using u
Bone-metastatic, castration-resistant prostate cancer (bmCRPC) represents a lethal stage of the most common noncutaneous cancer in men. The recent introduction of Radium-223 dichloride, a bone-seeking alpha particle (α)-emitting radiopharmaceutical, demonstrates statistically significant survival benefit and palliative effect for bmCRPC patients. Clinical results have established safety and effica
Objective: Type 2 diabetes is heterogeneous in its clinical features, pathogenesis, and predisposing or causal genetic factors. This report examines what is known and what needs to be learned about the potential to individualize glycemic therapies in type 2 diabetes, based on phenotypes and genotypes. Participants: A 29-member international working group with expertise in diabetes epidemiology, ph
Epithelial linings serve as physical barriers and produce antimicrobial peptides (AMPs) to maintain host integrity. Examples are the bactericidal proteins midkine (MK) and BRAK/CXCL14 that are constitutively produced in the skin epidermal layer, where the anaerobic Gram-positive coccoid commensal Finegoldia magna resides. Consequently, this bacterium is likely to encounter both MK and BRAK/CXCL14,
Methanol is a promising renewable fuel that can be used to reduce the carbon intensity of internal combustion engines. In any combustion strategy with methanol, both unburned methanol and formaldehyde emissions are criteria pollutants that are potential drawbacks, so their accurate measurement is critical. The flame ionization detectors (FIDs) typically used in engine research to measure unburned
Tonåringar utgör en viktig källa till flexibel och lågavlönad arbetskraft inom servicesektorn. Trots detta saknas forskning som belyser och problematiserar deras sysselsättningsmönster, anställningsvillkor och arbetserfarenheter – särskilt i en nordisk kontext. Denna avhandling analyserar gymnasieelever som arbetskraft i Sverige, i skärningspunkten mellan kundnära servicebranscher som är beroende Teenage students constitute an important source of flexible, low-cost labor in interactive service sectors. However, existing empirical research has primarily treated their labor as transitional, focusing on its impact on future employment or labor market outcomes. There remains a lack of knowledge about how these young workers experience and make sense of their early employment, particularly with
Purpose: The virtualization of work has been high on the agenda during the new millennium, increasingly so after the pandemic. In this transition, co-working spaces (CWS) are often proposed to be the future-proof solution. The purpose of this paper is to explore how hybrid and virtual solutions are portrayed in co-working literature and whether they are shaping CWS in practice. Design/methodology/
When it comes to random walk on the integers Z, the arguably first step of generalization beyond simple random walk is the class of one-sidedly continuous random walk, where the stepsize in only one direction is bounded by 1. Moreover, the time until state 0 is hit by left-continuous random walk on Z started at 1 has a direct connection to the total progeny in branching processes. In the analysis
Market-based climate policies have received increased attention, making it important to understand how they affect competition in the electricity market. This paper focuses on the green certificate policy which financially supports producers of renewably sourced electricity by means of tradable certificates, and develops a duopoly model that incorporates both the electricity and the green certific
Data-driven modeling frameworks have become essential tools for guiding surveillance strategies and informing public health policies across diverse population health challenges. Accurate, fine-scale disease estimates often lacking from direct surveys are critical for policy planning, given that spatial heterogeneity and nonlinear dynamics among determinants of health challenge classical models, li
Human–nature relationships are often framed positively, but research rarely addresses biophobia, the aversion to nature. However, negative relationships with nature are likely to become more widespread following societal and environmental changes, with serious implications for public health and conservation efforts. Here, we performed a systematic review of 196 studies on biophobia, revealing a fr
AbstractThe overall aim of this thesis was to explore women´s experiences of the second stage of labour, midwifery practices and the use of interventions.Methods: Study I is a retrospective cohort study where 764 medical records from 2017 were reviewed. Women in Robson group 1 were included. Descriptive and analytic statistics were used to describe the use of oxytocin and to compare mode of birth
This study examines the views of stakeholders involved in house renovations regarding the one-stop-shop business concept innovation, and assesses their level of preparedness to adopt such a concept in order to enter the promising market of detached house renovations. The investigation is based on 25 interviews with construction SMEs owners, real estate agents and loan consultants, and on a concept
Circular economy (CE) is still a nascent research field in the built environment, however, has gained traction in the last decade. Despite it being generally accepted that sustainability consists of three dimensions, namely, social, environmental, and economic, CE has been criticised for focusing on environmental and economic impact whilst neglecting the social aspect. Further, CE has been critici
Abstract: The aim of this chapter was to analyze associations between measures of cortisol in salivaand mental health and to see if divergent results were functions of the methods used. Measures ofmental health outcome included Major Depressive Disorder (MDD), symptoms of depression, andsymptoms of anxiety, Burnout (BO), and Vital Exhaustion (VE). Only studies on otherwise healthyindividuals were
Patients with type 2 diabetes (T2D) are at high risk of cardiovascular complications. Novel anti-diabetic medications such as sodium-glucose cotransporter-2 inhibitors (SGLT-2i) and Glucagon-like peptide-1 receptor agonists (GLP-1RA) have been shown to possess cardiac and renal protective effects beyond their ability to lower plasma glucose. Use of SGLT-2i and GLP-1RA in patients with T2D and hear
This study aimed examin the factors associated with the uptake and non-acceptance of COVID-19 vaccine booster doses among healthcare workers (HCWs) in South Africa. We used a mixed-methods design with data from a web-based self-administered survey followed by semi-structured in-depth interviews (IDIs) with selected participants. Of the 6235 HCWs included in our analysis who had fully vaccinated, 3
BackgroundThe primary aim of specialised palliative care (SPC) is to improve the quality of life (QoL) for patients with a high symptom burden from a life-threatening disease. This randomised study aimed to assess the QoL impact of early integration of SPC alongside tumour-specific palliative treatment in patients with gastrointestinal (GI) cancers.MethodsWe randomly assigned ambulatory patients w
