Filtyp
There is an increasing demand for trustworthy engineering geological conceptual models in urban areas due to an increasing trend in the underground infrastructure construction. Good-quality site investigations can reduce the risk of encountering unexpected geological conditions during construction. Geoelectrical measurements can be used as a tool for providing an overview of the site conditions an
Background: A scientifically sound validated foot and ankle specific score validated ab initio for different languages is missing. The aim of a project of the European Foot and Ankle Society (EFAS) was to develop, validate, and publish a new score(the EFAS-Score) for different European languages. Methods: The EFAS Score was developed and validated in three stages: (1) item (question) identificatio
The importance of natural IgM antibodies in protection against infections is still emerging and these antibodies have a potential role in the maintenance of homeostasis through clearance of apoptotic bodies, complement-dependent mechanisms, inflammation and exclusion of misfolded proteins. Natural IgM act as a first line of defence against unknown hazardous factors and are present in most vertebra
The extraction, supply, market price and recycling of the metals molybdenum and rhenium were modelled using an integrated system dynamics model. The resource estimates made here resulted in significantly larger estimates than earlier studies for molybdenum. Present molybdenum resources are about 75–80 million ton and about 7 million ton has been mined to date. The ultimately recoverable resources
Background: Older patients with a hip fracture require specialized emergency care and their first healthcare encounter before arriving at the hospital is often with the ambulance service. Since 2005 there has been a registered nurse on the crew of every ambulance in Sweden in order to provide prehospital emergency care and to prepare the patients for hospitalization. It is important to investigate
Introduction Randomised controlled trials (RCTs) conducted using cohorts and routinely collected health data, including registries, electronic health records and administrative databases, are increasingly used in healthcare intervention research. The development of an extension of the CONsolidated Standards of Reporting Trials (CONSORT) statement for RCTs using cohorts and routinely collected heal
OBJECTIVE: To evaluate speech in 5-year-olds with cleft palate with or without cleft lip (CP±L) treated with primary palatal surgery in 1 stage with muscle reconstruction according to Sommerlad at about 12 months of age.DESIGN: Retrospective study.SETTING: Primary care university hospital.PARTICIPANTS: Eight 5-year-olds with cleft soft palate (SP), 22 with cleft soft/hard palate (SHP), 33 with uni
Background: 18F-FDG-PET/CT has become a standard for assessing treatment response in patients with lymphoma. A subjective interpretation of the scan based on the Deauville 5-point scale has been widely adopted. However, inter-observer variability due to the subjectivity of the interpretation is a limitation. Our main goal is to develop an objective and automated method for evaluating response. The
Introduction: CD40 signaling activates dendritic cells leading to improved T cell priming against tumor antigens. CD40 agonism expands the tumor-specific T cell repertoire and has the potential to increase the fraction of patients that respond to established immunotherapies. Areas covered: This article reviews current as well as emerging CD40 agonist therapies with a focus on antibody-based therap
Human embryonic stem cells (hESC) and induced pluripotent stem cells (iPSC) provide new prospects for studying human neurodevelopment and modeling neurological disease. In particular, iPSC-derived neural cells permit a direct comparison of disease-relevant molecular pathways in neurons and glia derived from patients and healthy individuals. A prerequisite for such comparative studies are robust pr
Introduction: Pancreatic cancer is a highly lethal disease with a close association between incidence and mortality. First-line (FL) palliative chemotherapy prolongs survival and alleviates cancer-related symptoms. However, the survival benefit of second-line (SL) treatment is uncertain, as studies fail to consistently show prolonged survival for any given SL treatment, and in the absence of progn
Background: The ABILHAND questionnaire is recommended to assess perceived manual ability after stroke; however, more knowledge on interpretability is needed to improve the clinical applicability. Objectives: To determine clinically meaningful cutoff scores for different levels of perceived manual ability, assessed by ABILHAND, corresponding to established observed and perceived upper extremity ass
Uppsatsen analyserar lagförslaget om särskilda provokativa åtgärder och för-slaget om ändring i LUL som aktualiserar åtgärderna för barn under 15 år i SOU 2025:109. Förslagen analyseras mot barns rättigheter enligt barnkon-ventionen. De centrala artiklarna i barnkonventionen är 3.1, 16, 19, 33, 36 och 40. Syftet är att undersöka lagförslagens förenlighet med barnkonventionen ur ett barnrättsperspThis thesis analyses the legislative proposal on a new act regarding special provocative measures and the proposed legislative change in the act concern-ing specific provisions on young offenders (LUL), which makes such pro-vocative measures applicable to children under 15 years of age, in the official report SOU 2025:109. The proposals are analysed against children’s rights under the Convention o
Klimatförändringarna påverkar i allt större utsträckning både samhällen och fastighetsmarknaden. Även i Sverige väntas högre temperaturer och ökad nederbörd leda till större risk för klimatrelaterade skador på fastigheter och infrastruktur. Ett tydligt exempel är översvämningarna i Gävle 2021, som orsakade omfattande ekonomiska konsekvenser för fastighetsägare och försäkringsbolag. Fysiska klimatClimate change is increasingly affecting both societies and the real estate market. In Sweden as well, higher temperatures and increased precipitation are expected to lead to a greater risk of climate-related damage to properties and infrastructure. A clear example is the floods in Gävle in 2021, which caused extensive financial consequences for property owners and insurance companies. Physical c
Electricity demand in southern Sweden is expected to increase significantly in the coming decades. More electric cars, cleaner industries, and the phase-out of fossil fuels will require much larger amounts of electricity than today. At the same time, Skåne currently produces only part of the electricity it consumes and depends heavily on electricity imports from other regions and neighbouring coun
Background: Tumor multiplicity is a negative prognostic factor in intrahepatic cholangiocarcinoma (iCCA) and the role of surgical resection in multiple iCCA remains unclear. Patients and Methods: Data were extracted from the Swedish quality registry for cancers of the liver and biliary tract, for all patients undergoing surgery for iCCA (2010–2021). Validation was performed with all Swedish hepato
This thesis consists of four self-contained papers in the economics of education and labor economics.In the first chapter, we study whether differences in teacher quality across countries are a contributor of international learning gaps. In particular, we study the effects of two dimensions of teacher quality, subject knowledge and didactic skills, on student learning in francophone Sub-Saharan Af
Loss of genetic diversity threatens species survival, yet its dynamics and impacts can vary widely across species depending on their evolutionary histories, life-history traits, and demographic trajectories. To investigate these differences, we analyzed the genomes of 3 species that experienced extreme and well-documented population bottlenecks, the Mauritius parakeet, the Mauritius kestrel, and t
