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This pictorial review highlights cancers detected only at tomosynthesis screening and screens falsely recalled in the course of breast tomosynthesis screening, illustrating both true-positive (TP) and false-positive (FP) detection attributed to tomosynthesis. Images and descriptive data were used to characterise cases of screen-detection with tomosynthesis, sourced from prospective screening trial

Background: Prostate cancer ranks as the second most lethal malignancy in the Western world. Previous targeting of prostate-specific antigen and human kallikrein-related peptidase 2, two related enzymes abundantly expressed in prostatic malignancies, with radioimmunoconjugates intended for diagnostic purposes, have proven successful in rodent prostate cancer (PCa) models. In this study, we investi

Aggrecan fragments are released from human joint cartilage matrix into joint fluid after injury and in osteoarthritis (OA). The temporal patterns of release agree with changes in synthesis and degradation of aggrecan found in experimental animal models of OA. However, we are far from being able to use these molecular fragments to monitor human OA. The structures of the aggrecan fragments remaining

Popular Abstract in Swedish Svensk Kärnbränslehantering AB, SKB, har i uppdrag att ta hand om allt radioaktivt avfall från de svenska kärnkraftverken. En av förutsättningarna för att SKB ska få tillstånd att uppföra inkapslings- och slutförvars¬anläggningarna är att metod och teknik för att försluta kapslarna finns. De förslutna kapslarna ska uppfylla de krav på långsiktig säkerhet som SKB, myndigThis thesis presents the development to reliably seal 50 mm thick copper canisters containing the Swedish nuclear waste using friction stir welding. To avoid defects and welding tool fractures, it is important to control the tool temperature within a process window of approximately 790 to 910°C. The welding procedure requires variable power input throughout the 45 minute long weld cycle to keep th

Heart transplantation (HTx) is severely limited by a shortage of donors. This thesis aimed to investigate the effectof variables used to match donors to recipients in HTx.Methods: Data from the ISHLT registry was used to study: I: Identical versus compatible non-identical ABOmatchingin 3,589 AB HTx recipients. II: Outcomes of 94 ABO-incompatible transplants were compared to anABO-compatible group.

Homelessness as a political and social dominion has a number of features that make it particularly difficult to tackle. In addition to being a wicked problem, homelessness offers several analytical avenues. How do these characteristics affect the evaluation of programmes and projects aspiring to combat homelessness? Dissimilar pictures and solutions regarding homelessness in the US and in European

Building materials differ in their susceptibility to mould growth. Wood is a material often considered to have a low mould resistance. However, wood is not a homogenous material and different characteristics of the material are expected to have an impact on mould growth. In this paper, it was shown that wood species (pine or spruce), sawing pattern (centre-board or side-board) and surface structur

”...like hitting yourself with a hammer” – A qualitative study of four former drug addict´s ways into- and ways out of addiction The purpose of this study was to describe and understand four former drug addict´s own experiences of developing an addiction and their ways towards abstinence from drugs. The three main questions I wanted to have answered were: How did the former addicts end up in an a

Shortly after the start of the transition from planned to market economy in Central and Eastern Europe and the former Soviet Union, an overall drastic fertility decrease began in all the countries of this region. This thesis focuses on the theoretical and empirical connection between transition and fertility. With the use of Gary Becker´s New Home Economics as a theoretical framework, fer­tility d

Denna uppsats jämför de lagstiftningstekniker som valdes av Sverige respektive Storbritannien för att implementera den del av Postdirektivet som omfattar de samhällsomfattande posttjänsterna och vilka resultat respektive land har uppnått. Den utvärderar även EU:s val av regleringsmetod. Motivet bakom Postdirektivet, som trädde ikraft 1997, var EU:s vilja att försäkra invånarna tillgång till samhäThis essay compares the different ways that Sweden and Great Britain respectively chose to implement the part of the Postal Directive that include the universal services and the results that have been achieved by each country. It also evaluates the EU's choice of regulatory approach. The motive behind the Postal Directive, which came into force in 1997, was the EU's desire to assure resid

Background: Neuroimaging with magnetic resonance imaging (MRI) may assist clinicians in evaluating brain injury and optimising care in comatose adults resuscitated after out-of-hospital cardiac arrest (OHCA). However, contemporary international data on its use are lacking. Aim: The primary aim was to compare the patient characteristics, early postresuscitation care, and neurological outcomes of pa

Parkinson’s disease (PD) is a progressive neurodegenerative disease, characterized by degeneration of dopaminergic neurons, leading to notable difficulties with one’s movement. Among different treatment options, stem cell replacement therapies have been recognized as an option to not only treat disease symptoms but to address its underlying cause- neuronal degeneration. This can be achieved throug

Rationale, Aims and Objectives: Colonoscopy, though common, can be uncomfortable, necessitating routine assessment of patient experience per European guidelines. Positive patient experiences are crucial as they influence willingness for repeat procedures. Patient-reported experience measures (PREMs) effectively capture patient perspectives through surveys, empowering patients to influence healthca

Continuous-flow fixed-bed reactors effectively bridge laboratory research and industrial production. As the key component, the catalyst module must demonstrate high catalytic activity and rapid reactant distribution to maximize the catalytic turnover. Herein, a facile strategy is proposed to fabricate a microfibrous catalyst by decorating Cu single atoms (Cu1) on composite microfiber (CMF) made fr